The Breitling group is interested in using computational approaches to understand complex biological systems, ranging from microbes to man. Two main strategies dominate our work: on the one hand, we develop methods to interpret “molecular profiles”, e.g. the global patterns of gene expression or the abundance of small molecules (metabolites) in biological samples. On the other hand, we develop quantitative models to describe and predict the behaviour of cells, e.g. after drug treatment or genetic manipulation.
Rainer Breitling studied biochemistry at the University of Hannover, Germany, and received his Ph.D. from the Technical University of Munich, Germany, in 2001. He held postdoctoral positions as a bioinformatician at San Diego State University (California, USA) and the University of Glasgow (UK), followed by professorial appointments at the University of Groningen (The Netherlands) and the University of Glasgow. Since September 2012 he is Professor of Systems Biology at the Manchester Institute of Biotechnology, University of Manchester.