Dr Rachelle DonnMB ChB PhD

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Overview

My area of research is complex disease genetics. This applies to conditions where multiple genes interplay with environmental triggers.

I use both genetic and functional approaches to further the understanding of:

 (i) The commonest inflammatory arthritis to affect children under 16 years – Juvenile Idiopathic Arthritis.

(ii) Changes that arise with weight variation    a.  Obesity

                                                                         b.  Bariatric surgery

                                                                         c. Diabetes (T2DM, T1D, GDM)

(iii) Inflammatory pathologies, especially where variation in steroid sensitivity is a factor (eg SLE).

Biography

Rachelle Donn MB ChB PhD

Expertise in: Molecular Genetics and Functional Genomics.

Main Research interests:

1) Genetics of complex diseases (Juvenile Idiopathic Arthritis, Diabetes, Systemic Lupus Erythematosus)

2) Genetic basis of drug response (Steroids)

3) Network analysis of complex genetic diseases

Social responsibility

The Healthy City Initiative is a long term, sustainable endeavour to improve the health of Salford residents, principally by educating and monitoring in relation to type 2 diabetes. The has fed forwards into more funding coming to Salford for extended projects related to wider, related public health issues such as the national diabetes prevention programme. I am chair of the streeing group for the Healthy City Initiative and liaise regularly with Diabetes UK in relation to this long term project.

Qualifications

  • July 1988 MB. Ch.B. Graduation in Medicine and Surgery, University of Sheffield: Winner of The Undergraduate Prize for Medicine & Surgery (Chairman's Cup)
  • July 1995 Ph.D. Faculty of Medicine, University of Manchester
  • July 1999 MRC Research Fellow
  • June 2015 Senior Fellow The Higher Education Academy

Memberships of committees and professional bodies

  • Royal Society of Medicine
  • British Society for Adolescent and Paediatric Rheumatology
  • British Society of Rheumatology
  • HeartUK
  • Diabetes UK
  • British Inflammation Research Association

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