I am a Breast Cancer Now funded Research Associate based at the Manchester Cancer Research Centre.
My research interests are in metastatic cancer, particularly how normal cells in the microenvironment of metastatic sites promote cancer cell colonisation and growth. My research focusses particularly on identifying signalling pathways between normal and cancer cells, and determining if by blocking these signals we can prevent metastatic cell growth. As metastasis is the main cause of death in breast cancer patients, ultimately I hope that by a better understanding the metastatic process, we will have the potential to save many lives.
My current project focusses on breast cancer bone metastasis, with a particular emphasis on cancer stem cell colonisation within the bone niche. However in the future, I plan to expand my research further to explore other cancer types and other metastatic sites through utilising state of the art in vitro models and patient derived xenograft models in vivo.