Prof Pippa Tyrrell MD, FRCP

Emeritus Professor

View graph of relations


I am Professor of Stroke Medicine and an Honorary Consultant in Stroke Medicine at the Comprehensive Stroke Centre at Salford Royal Foundation Trust. My research interests include translational studies of immunomodulation after acute ischaemic stroke and subarachnoid haemorrhage, studies in stroke rehabilitation and implementation studies in stroke. I was Clinical Lead for the NICE Acute Stroke and TIA Guideline (2006-8) and contributed to the 2016 National Clinical Guideline for Stroke. Until 2013 I was Clinical Lead for Stroke in Greater Manchester and led the Manchester stroke service redesign from 2007. I am Associate Director of the Royal College of Physicians Stroke programme with responsibility for the National Stroke Audit, SSNAP.  I am Vice Chair (Medical) and  Trustee of the Stroke Association and Chair of its Research Awards Panel.


I graduated from the University of Cambridge in 1978 with a first in Medical Sciences, and from the University of London (London Hospital Medical College) in 1981. I trained in General Medicine and Neurology in London (St Bartholomew's Hospital and St Mary's). From 1986-90 I was a Research Fellow at the MRC Cyclotron Unit, London and National Hospital Queen Square, where I studied the relationship between clinical features and PET scan appearances in various forms of degenerative dementia. As a Senior Registrar in Geriatric and General Medicine in London I became interested in stroke, and after completing clinical training in Manchester in  1995,  I was  appointed Consultant in Stroke Medicine in Salford. I was the first designated Stroke Physician in Manchester, and set up a nationally leading stroke service singlehandedly. In 1999, I was awarded my first research grant in collaboration with Professor Nancy Rothwell and was appointed Senior Lecturer in the University of Manchester in 2006. I am Clinical Lead to the Greater Manchester Clinical Stroke Network and have led a nationally leading redesign of stroke services. I was Clinical Advisor to the NICE guideline on Acute Stroke and TIA 2006-8, and lead the National Stroke Audit (SINAP) at the RCP. I was  RGL to the Clinical Neurosciences Group 2006-2009; Clinical Neurosciences Clinical Governance Lead 2004-2007;  and  Clinical Lead, NW Stroke Research Network (2006-13). This was the leading Stroke LRN for recruitment into RCTs and has brought clinicians from across the NW into research.  I undertake  translational research with Professor Nancy Rothwell, Professor Stuart Allan, Professor Andrew King, Professor Craig Smith, Dr Adrian Parry-Jones, Mr Hiren Patel and others   in neuroinflammation in stroke and subarachnoid haemorrhage. I am involved in studies of cognition following stroke, led by Professor Audrey Bowen, and studies of motor control and balance (Professor Sarah Tyson). I was   lead for the Stroke Implementation Programme of the first GM CLAHRC (2008-13) and led on the development of the Greater Manchester Stroke Assessment Tool (GM-SAT) which is now in clinical use across many parts of the NHS. I support the Stroke Programme in GM CLAHRC 2 which is delivering a new version of the GM-SAT for care home use and a carer support study. I am recognised nationally and regionally as an expert in clinical stroke management and lead an exciting and productive research programme. I have also been very involved in the delivery of stroke services within SRFT to a high standard, improving delivery of acute services including  thrombolysis and interventional procedures to patients from across GM. This service redesign has been the subject of an influential NIHR study on service redesign in the NHS. 

Social responsibility

I was involved in Science Stroke Art 2014 (, #SSA14), a unique partnership between the University of Manchester and the Stroke association, together with a number of cultural organisations across the NW. This ran throughout May 2014 and included talks, theatre, story-telling, science and art demonstrations to capture people's imaginations and challenge misconceptions about stroke. This project developed into "Stories of the Self Through Science and Art" (2015-16). 

I am a Trustee of the Stroke Association and its Medical Vice Chair. I chair my local transition town group and help organise a community garden, a project to restore a peat bog and other community activities related to raising awareness of climate change and sustainability.



  • BA (Hons) 1st Class University of Cambridge 1978
  • MB. BS (Hons) University of London 1981
  • MA (Cantab) 1982
  • MD (University of London) 1991
  • FRCP (London) 2000

Memberships of committees and professional bodies

  • Member of the Scientific Committee, The Stroke Association (2006-2010)
  • Member of the Scientific Committee, British Association of Stroke Physicians 2000-2003; 2004-2007
  • Member of the British Association of Stroke Physicians
  • Member of the Executive Committee, British Association of Stroke Physicians 2009-12
  • Member IDSMC: STASH study
  • Member, IDSMC, NIHR funded DARS study
  • Clinical Lead, SSNAP (RCP) and Associate Director, Stroke Programme, Royal College of Physicians 2008-date
  • Clinical Lead, GM Clinical Stroke Network 2007-13
  • Chair, Scientific Committee,  Stroke Association, 2012-
  • Trustee, Stroke Association 2012-
  • Vice Chair (Medical) Stroke Association 2014-date

External positions

Medical Vice Chair, The Stroke Association

31 Aug 2014 → …

Areas of expertise

Research Beacons, Institutes and Platforms


  • stroke; inflammation; immunology; pneumonia; oral hygiene; dysphagia

Related information