Dr Pawel Grzechnik

Lecturer in Bioscience

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Overview

Pawel is a molecular biologist interested in mechanisms regulating RNA synthesis in eukaryotic cells. His lab studies how proteins interacting with RNA Polymerase II control transcription and co-transcriptional RNA processing in human and model organisms. 

Pawel received a PhD in Biology at the University of Warsaw in the lab of Prof Joanna Kufel where he characterized the maturation of small nucleolar RNAs. Next, he joined Prof. Nick Proudfoot‘s lab in the Sir William Dunn School of Pathology, University of Oxford. As a postdoctoral researcher, he studied mechanisms governing transcription termination and 3’ end processing of coding and non-coding RNAs. After his postdoctoral training, Pawel was awarded Sir Henry Dale Fellowship to establish his lab at the University of Birmingham where he expanded his research on the regulation of nuclear RNA biology in the context of cancer, neurodevelopment and viral infections. In 2022 Pawel joined the University of Manchester as a lecturer.

Biography

2022 – present: Lecturer, School of Biological Sciences, University of Manchester

2016 – 2022: Group leader, Sir Henry Dale Fellow, School of Biosciences, University of Birmingham

2009 – 2016: Postdoctoral researcher, Sir William Dunn School of Pathology, University of Oxford

2003 – 2008: PhD studies, Institute of Genetics and Biotechnology, University of Warsaw

Biology, Medicine and Health (BMH) Domains

Keywords

  • RNA, transcription, regulation of gene expression, genetic disorders

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Publication highlights

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