Dr Nathan Hawkshaw

Overview

Based in the Centre for Dermatology my research focus is to understand the molecular mechanisms that underpin cutaneous diseases (e.g. alopecia and photodermatoses) and identify novel therapeutic targets that can be pharmacologically targeted. To do this I use clinical in vivo and ex vivo skin and a variety of genomic (RNAseq, microarray, nanostring, single molecule in situ hybridisation) and pharmacological (siRNA, small molecule inhibitors, recombinant proteins, clinical drugs) approaches to gain insight into which cells and signalling pathways are responsible for driving these diseases. My recent work involves examining how human skin resolves after exposure to UVR-inflammation, identifying the initiating triggers of solar urticaria and understanding the molecular mechanisms that enhance human hair growth.

Biography

2017-Present: Postdoctoral researcher within NIHR Biomedical Research Centre (BRC) at the University of Manchester (photodermatoses research theme).

2013- 2017: PhD studentship awarded by Guiliani S.p.A at University of Manchester. Thesis title:An immunopharmacological approach to identifying novel targets for human hair growth stimulation: From cyclosporine A to Wnt signalling. Supervisor: Prof R. Paus.

Memberships of committees and professional bodies

The European Society for Dermatological Research (ESDR).