Dr Mick BrownPhD.

Research Fellow

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Overview

In my current position I am a Research Fellow directing the scientific research arm of the Genito Urinary Cancer Research Group led by Professor Noel Clarke. The main research focus of the group is understanding the mechanism of metastasis in prostate cancer, especially the targeted metastasis towards the bone. Recent discoveries within the group has highlighted the role of specific polyunsaturated fatty acids in directing the metastatic process. We also have an active interest in the characterisation of new diagnostic and prognostic biomarkers and the isolation of cancer stem cells from bladder, renal and testicular cancer. This includes a long standing collaboration with Professor Peter Gardner's Analytical and Biomedical Spectroscopy group at the MIB, University of Manchester.

Biography

Current Post:

08/2013- Institute of Cancer Sciences, University of Manchester (Research Fellow). Genito Urinary Cancer Research Group.  Conducting research into prostate cancer metastasis (the role of lipid metabolism), prostate cancer stem cells, molecular diagnostics, prostate cancer radiobiology and, renal, testicular and bladder stem cell biology.

Summary of Previous Posts: (with dates)

2002- 07/2013 Paterson Institute for Cancer Research (Associate Scientist). Genito Urinary Cancer Research Group. Conducting research into prostate cancer metastasis, prostate cancer stem cells, molecular diagnostics, prostate cancer radiobiology and, renal, testicular and bladder stem cell biology.

2000-02 ICRF Clinical Centre in Leeds (Research Fellow). Targeting expression of tumour antigens to dendritic cells in an in vitro embryonic stem cell system. Supervisor Prof. Poulam Patel

1997-99 CRC Paterson Institute (Post Doc). New approaches to immunotherapy of human papillomavirus-associated cervical neoplasia. Supervisors Dr Simon Stacey and Prof. Peter Stern

1995-97 CRC Paterson Institute (Post Doc). Development of HPV E6 and E7 fowlpox recombinants and analysis of CTL responses to these recombinants. Supervisors Dr Simon Stacey and Prof. Peter Stern

Qualifications

2nd Degree Ph.D. in Molecular Virology; Institute for Animal Health, Compton - University of Reading.1991 - 1995

1st Degree B.Sc. (Hons.) 2:1 Microbiology; University of Leeds 1988 - 1991

Memberships of committees and professional bodies

  • American Urology Association (AUA)
  • American Society of Clinical Oncology (ASCO)
  • European Urological Association
  • Young Prostate Researchers
  • EACR
  • BACR
  • Prostate Cancer UK Reasearch Advisory Committee Member

External positions

Research Fellow, Imperial Cancer Research Fund Clinical Centre in Leeds

Jan 2000Mar 2002

POSTDOCTORAL SCIENTIST, Paterson Institute for Cancer Research

May 1995Dec 1999

Research Networks and Beacons

Biology, Medicine and Health (BMH) Domains

Keywords

  • Prostate Cancer, Bone metastasis, Bone marrow, co-cultures, bladder cancer, Tissue micro arrays

Education / academic qualifications

  • 1995 - Doctor of Philosophy, Sequence Analysis of European Very Virulent Isolates of Infectious Bursal Disease Virus, The University of Reading (1991 - 1995)
  • 1991 - Bachelor of Science, Microbiology, University of Leeds (1988 - 1991)

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