Dr Melissa Scholefield

Research Associate

Affiliations:
Links:
ORCID: 0000-0002-6810-0986
View graph of relations

Overview

PhD investigating metallomic, metabolomic, and proteomic disturbances in the brains of Parkinson's disease dementia (PDD) and Dementia with Lewy Bodies (DLB) patients.

Primary Aim: To identify metallomic, metabolomic, and proteomic disturbances in the brains of Parkinson's disease dementia (PDD) and Dementia with Lewy Bodies (DLB) patients.

Secondary Aim: To compare results from these analyses with previous investigations performed on the brains of Alzheimer's disease and Huntington's disease patients in order to establish the presence of any shared causes or mechanisms of disease.

Biology, Medicine and Health (BMH) Domains

Education / academic qualifications

  • 2018 - Master in Science, MSc in Translational Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield (2016 - 2017)
  • 2015 - Bachelor of Science, BSc (Hons) in Neuroscience, University of Dundee (2011 - 2015)

Related information

Publications

Contrasting Sodium and Potassium Perturbations in the Hippocampus Indicate Potential Na +/K +-ATPase Dysfunction in Vascular Dementia

Research output: Contribution to journal › Article › peer-review

Severe and Regionally Widespread Increases in Tissue Urea in the Human Brain Represent a Novel Finding of Pathogenic Potential in Parkinson's Disease Dementia

Research output: Contribution to journal › Article › peer-review

Substantively lowered levels of pantothenic acid (vitamin B5) in several regions of the human brain in Parkinson’s disease dementia

Research output: Contribution to journal › Article › peer-review

View all (8)

Student Theses

A Shared Metabolic Basis for Parkinson's, Alzheimer's, and Huntington's

UoM administered thesis: Doctoral Thesis

View all (1)