Mr Jack Barrington


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A member of the brain inflammation group, Jack's research is focussed on understanding the role of inflammation after intracerebral haemorrhage. In particular, Jack is establishing how the master cytokine interleukin-1 drives the recruitment of immune cells to the brain post-ictus and, in turn, how these actively recruited cells mediate detrimental and beneficial processes seen in this devastating pathology.

Alongside his main work, Jack has contributed to projects investigating how caspase-1 signalling platforms, termed inflammasomes, control inflammation in pathologies such as cerebral malaria and ischaemic stroke.


  • ICH, Brain, Inflammation, inflammasome, Interleukin, IL-1, Neuroinflammation, Stroke, Immunology

Education / academic qualifications

  • 2015 - Bachelor of Science, BSc (Hons) Biomedical sciences with industrial experience, First class

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