Dr Ilaria RussoPhD

Honorary Lecturer (Teaching & Research)

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Biography

Born in Palermo on the 29th of January 1974, after a bright academic carrier she pursued a master degree in Pharmaceutical Chemistry and Technology in 1998 with 110/110 cum laude, at University of Padua.

As eagle-scout she had the opportunity to do important extra-academic experiences volunteering in projects for homeless, immigrants and street teenagers. A crucial experience was in the summer of 1994, that was spent as volunteer in a mission in Tanzania. Here, she learned some basic of the local language, Kiswahili, and working at little hospitals in the Savannah (Ismani and Migoli regions) directly experienced the social devastation that neglected infection diseases cause on sub-Saharian countries, (Malaria, TB, Leprosy, Filariasis, intestinal infections and HIV). As she recovered from malaria and returned in Italy, she matured a strong motivation to devote her research on infectious diseases.

For one and half more years she worked on anticoagulants (same topic of her graduation thesis) under the direction of prof. A Fontana at University of Padua. A collaboration gave her the opportunity to visit one of the top five universities for MDs in USA, the Washington University School of Medicine in St. Louis. Here, she worked with prof. E. Di Cera, a master of enzymology, learning high standard approach of doing research. Then following her desire to do research on infectious diseases, she accepted the job offered by Chiron Vaccine Research Centre (now Novartis) in Siena.

Under the direction of Dr. R. Rappuoli and Dr. A. Covacci, she worked for three years on a novel project, oriented to target discovery for new antimicrobials. Within the period spent at Chiron she had also the opportunity to start her PhD course on a joined collaborative project with the University of Padua under the mentorship of prof. C. Montecucco. During these years she worked mostly on Helicobacter pylori and Streptococcus pneumonia but also had experience on Staphylococcus aureus, Neisseria meningitides accomplishing Chiron’s objective for target discovery, her PhD project on Helicobacter virulence factors as well as the setup of Streptococcus pneumonia vaccine project.

Completed her PhD in Cellular and Molecular Biology and Pathology, she moved to USA seeking both the best formative offer for a post-doctoral training and her personal interest for studying malaria. The choice fell on prof. Daniel E. Goldberg, that conducts one of the malaria milestone laboratories at Washington University School of Medicine in St. Louis. Here, she specialized in the study of Plasmodium falciparum, the deadliest strain causing malaria and one of the most difficult to approach for significant technical issues. She faced challenging projects on two previously uncharacterized enzymes, Calpain and PlasmepsinV, disclosing their functions and publishing on them as first author in important international journals (PNAS, Molecular Microbiology and Nature).

During her post-doc she developed thoroughly her abilities to conduct independent research, to direct a group of people, to establish and fulfill external collaborations and to set new genetic and biochemical tools. Therefore, she matured the decision to move to UK in order to accomplish the next step of her carrier: the establishment of her own laboratory on malaria

External positions

visiting Associate professor, Washington University in St Louis

Jul 2017 → …

Areas of expertise

  • QD Chemistry - PHARMACEUTICAL CHEMISTRY, Drug discovery, DRUG TARGET, hIGH THROUGHPUT SCREENING
  • QR180 Immunology - MALARIA, PARASITOLOGY, INFECTIOUS DISEASES, GENETICS, CELL BIOLOGY, MICROSCOPY

Keywords

  • Malaria, infectious diseases, molecular microbiology, enzymology, protein chemist

Education / academic qualifications

  • 2006 - Infectious Diseases Scholar - Training for interdisciplinary approaches and translational research conjugating clinical practice (patient based), clinical research and basic research in the field of infectious diseases, Department of Internal Medicine, Washington University
  • 2005 - Doctor of Philosophy, Cellular and Molecular Biology and Pathology at the Department of Biomedical Sciences,, Universita Degli Studi di Padova (2002 - 2004)
  • 1998 - Habilitation, Qualified Pharmacist, Universita Degli Studi di Padova
  • 1998 - Master of Pharmacy, Pharmaceutical Chemistry and Technology - Laurea Magistrale equivalent to BPharm & MPharm, Department of Biomedical Sciences and CRIBI Biotech Center, University of Padua (1992 - 1998)

Related information

Activities

Activity: Publication peer-review and editorial workPublication peer-review

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