I head the Quantitative Biomedical Imaging Lab (QBI Lab). QBI Lab focuses on magnetic resonance imaging (MRI) and other modalities with state-of-the-art analysis techniques to provide quantitative information about the structure and function of both normal and diseased tissues. Our research is a mix of methodological innovation and collaborative research projects with clinicians and industry. We currently enjoy funding from industry, the Engineering and Physical Sciences Research Council (EPSRC), Cancer Research UK, and the Medical research Council (MRC), with on-going research projects in:
- Quantitative DCE-MRI in oncology, inflammatory lung disease and dementia
- Tracer kinetic modeling methods
- Image registration
- Tumour growth patterns
- Tumour oxygenation
- Proton MRI functional lung imaging
- Tissue microstructure measurements using diffusion MRI and other methods in neuroscience and cancer
QBI Lab has also participated in a number of phase I clinical trials of anti- angiogeneic and antivascular agents using DCE-MRI in the quantification of tumour microvascular function.
I am Founder of a University of Manchester spin out company, Bioxydyn Limited. The company provides an advanced imaging biomarkers contract research service to both the pharmaceutical industry and academia.