Accommodation, refractive surgery and ocular aberrations

UoM administered thesis: Phd

  • Authors:
  • John Taylor


The principal work in this thesis describes the investigation of the impact that alterations to ocular aberrations following refractive surgery have on the accommodative mechanism. A series of prospective studies were conducted with healthy adults (n=36) that had chosen to undergo refractive surgery at Manchester Royal Eye Hospital. A variety of monocular accommodative functions were assessed prior to surgery and then at one and three months following surgery on the same cohort of patients. Accommodative functions included amplitude of accommodation, accommodative facility (at 6m and 0.4m) including positive and negative response times, and accommodative stimulus-response functions. Dynamic accommodation responses were examined in a subgroup (n=10) at three months following refractive surgery and compared to an age-matched emmetropic control group (n=10) to evaluate differences in latency, amplitude, time constant and peak velocity of accommodation and disaccommodation. During the studies, ocular aberrations were concurrently measured to determine whether alterations to aberrations could help explain any observed changes in accommodative functions. Evaluation of visual, refractive and questionnaire outcome measures indicated that the patient cohort underwent successful surgery. Following surgery, significant alterations to a number of accommodative functions were discovered. Mean subjective ocular amplitude of accommodation increased by approximately 0.50D (p


Original languageEnglish
Awarding Institution
Award date1 Aug 2011