Prof Tim HardinghamBSc, PhD, DSc

Assistance, Emeritus Professor

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Publications

  1. 2019
  2. E-pub ahead of print

    Enhanced chondrogenesis from human embryonic stem cells

    Wang, T., Nimkingratana, P., Smith, C. A., Cheng, A., Hardingham, T. & Kimber, S., 9 Jul 2019, In : Stem Cell Research.

    Research output: Contribution to journalArticle

  3. Published
  4. Published

    Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilage

    Ajekigbe, B., Cheung, K., Xu, Y., Skelton, A. J., Panagiotopoulos, A., Soul, J., Hardingham, T. E., Deehan, D. J., Barter, M. J. & Young, D. A., 2019, In : Osteoarthritis and Cartilage.

    Research output: Contribution to journalArticle

  5. 2018
  6. Published

    Stratification of knee osteoarthritis: two major patient subgroups identified by genome wide expression analysis of articular cartilage.

    Soul, J., Dunn, S., Anand, S., Serracino-Inglott, F., Schwartz, J-M., Boot-Handford, R. & Hardingham, T., Mar 2018, In : Annals of the rheumatic diseases. 77, p. 423-430

    Research output: Contribution to journalArticle

  7. 2016
  8. Published

    PhenomeScape: a Cytoscape app to identify differentially regulated sub-networks using known disease associations

    Soul, J., Dunn, S., Hardingham, T., Boot-Handford, R. & Schwartz, J-M., 15 Dec 2016, In : Bioinformatics (Oxford, England). 32, 24, p. 3847-9

    Research output: Contribution to journalArticle

  9. Published

    Gene expression changes in damaged osteoarthritic cartilage identify a signature of non-chondrogenic and mechanical responses

    Dunn, S., Soul, J., Anand, S., Schwartz, J-M., Boot-Handford, R. & Hardingham, T., Aug 2016, In : Osteoarthritis and Cartilage. 24, 8, p. 1431-1440 10 p.

    Research output: Contribution to journalArticle

  10. 2015
  11. Published
  12. 2014
  13. Published

    Cartilage Repair Using Human Embryonic Stem Cell-Derived Chondroprogenitors.

    Cheng, A., Kapacee, Z., Peng, J., Lu, S., Lucas, R. J., Hardingham, T. E. & Kimber, S. J., 1 Oct 2014, In : Stem Cells Translational Medicine. p. 1-8 7 p., original article.

    Research output: Contribution to journalArticle

  14. Published

    Assembly of the respiratory Mucin MUC5B a new model for a gel-forming Mucin

    Ridley, C., Kouvatsos, N., Raynal, B. D., Howard, M., Collins, R. F., Desseyn, J. L., Jowitt, T. A., Baldock, C., Davis, C. W., Hardingham, T. E. & Thornton, D. J., 6 Jun 2014, In : Journal of Biological Chemistry. 289, 23, p. 16409-16420 11 p.

    Research output: Contribution to journalArticle

  15. Published

    Generating Cartilage Repair from Pluripotent Stem Cells

    Cheng, A., Hardingham, T. & Kimber, SJ., 2014, In : Tissue Engineering. Part B. Reviews . 20, 4, p. 257-266 9 p.

    Research output: Contribution to journalArticle

  16. 2010
  17. Published

    Order within disorder: Aggrecan chondroitin sulphate-attachment region provides new structural insights into protein sequences classified as disordered

    Jowitt, T. A., Murdoch, A. D., Baldock, C., Berry, R., Day, J. M. & Hardingham, T. E., Dec 2010, In : Proteins: Structure, Function and Bioinformatics. 78, 16, p. 3317-3327 10 p.

    Research output: Contribution to journalArticle

  18. Published

    The potential of stem cells in the treatment of knee cartilage defects

    Khan, W. S., Johnson, D. S. & Hardingham, T. E., Dec 2010, In : The Knee. 17, 6, p. 369-374 5 p.

    Research output: Contribution to journalArticle

  19. Published

    Directed differentiation of human embryonic stem cells toward chondrocytes

    Oldershaw, R. A., Baxter, M. A., Lowe, E. T., Bates, N., Grady, L. M., Soncin, F., Brison, D. R., Hardingham, T. E. & Kimber, S. J., Nov 2010, In : Nature biotechnology. 28, 11, p. 1187-1194 7 p.

    Research output: Contribution to journalArticle

  20. Published

    Fell-Muir lecture: Cartilage 2010 - The known unknowns

    Hardingham, T. E., Jun 2010, In : International Journal of Experimental Pathology. 91, 3, p. 203-209 6 p.

    Research output: Contribution to journalArticle

  21. Published

    Notch signaling during chondrogenesis of human bone marrow stem cells

    Oldershaw, R. A. & Hardingham, T. E., Feb 2010, In : Bone. 46, 2, p. 286-293 7 p.

    Research output: Contribution to journalArticle

  22. Published

    Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy

    Brew, C. J., Clegg, P. D., Boot-Handford, R. P., Andrew, J. G. & Hardingham, T., Jan 2010, In : Annals of the rheumatic diseases. 69, 1, p. 234-240 6 p.

    Research output: Contribution to journalArticle

  23. Published

    A chemically-defined protocol for generating chondrocytes from human embryonic stem cells.

    Oldershaw, RA., Baxter, MA., Lowe, ET., Bates, N., Grady, LM., Soncin, F., Brison, DR., Hardingham, TE. & Kimber, SJ., 2010, In : Nature biotechnology. 28, 11

    Research output: Contribution to journalArticle

  24. Published

    Gene expression in human chondrocytes in late OA is changed in both fibrillated and intact cartilages without evidence of generalised chondrocyte hypertrophy

    Brew, CJ., Clegg, PD., Boot-Handford, R., Andrews, TE. & Hardingham, T., 2010, In : Annals Rheum Dis. 467

    Research output: Contribution to journalArticle

  25. Published

    Hardingham T (2010) Cell and Tissue-based Approaches for Cartilage Repair

    Hardingham, T., 2010, In : ALTERNATIVES TO LABORATORY ANIMALS. 38, p. 35-39

    Research output: Contribution to journalArticle

  26. 2009
  27. Published

    The epitope characterisation and the osteogenic differentiation potential of human fat pad-derived stem cells is maintained with ageing in later life

    Khan, W. S., Adesida, A. B., Tew, S. R., Andrew, J. G. & Hardingham, T. E., Feb 2009, In : Injury. 40, 2, p. 150-157 7 p.

    Research output: Contribution to journalArticle

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