Prof Tim HardinghamBSc, PhD, DSc

Assistance, Emeritus Professor

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Publications

  1. Published

    Human meniscus cells in 3D pellet culture under hypoxia are chondrogenic: this is accompanied by upregulation of prolyl 4-hydroxylase type 1.

    Adesida, A., Tweats, L., Millwards-Sadler, J., Salter, D. & Hardingham, TE., 2005, In : International Journal of Experimental Pathology. 86

    Research output: Contribution to journalArticle

  2. Published

    Human meniscus cells express hypoxia inducible factor-1alpha and increased. SOX9 in response to low oxygen tension in cell aggregate culture

    Adesida, AB., Grady, LM., Khan, WS., Millward-Sadler, SJ., Salter, DM. & Hardingham, TE., 2007, In : Arthritis Research and Therapy. 9, 4

    Research output: Contribution to journalArticle

  3. Published

    The matrix-forming phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia

    Adesida, A. B., Grady, L. M., Khan, W. S. & Hardingham, T. E., 17 Mar 2006, In : Arthritis Research and Therapy. 8, 3, R61.

    Research output: Contribution to journalArticle

  4. Published

    Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilage

    Ajekigbe, B., Cheung, K., Xu, Y., Skelton, A. J., Panagiotopoulos, A., Soul, J., Hardingham, T. E., Deehan, D. J., Barter, M. J. & Young, D. A., 2019, In : Osteoarthritis and Cartilage.

    Research output: Contribution to journalArticle

  5. Published

    Hyaluronan binding to Link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH

    Boon, C. H., Gribbon, P. M., Day, A. J. & Hardingham, T. E., 21 Nov 2008, In : Journal of Biological Chemistry. 283, 47, p. 32294-32301 7 p.

    Research output: Contribution to journalArticle

  6. Published

    Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy

    Brew, C. J., Clegg, P. D., Boot-Handford, R. P., Andrew, J. G. & Hardingham, T., Jan 2010, In : Annals of the rheumatic diseases. 69, 1, p. 234-240 6 p.

    Research output: Contribution to journalArticle

  7. Published

    Gene expression in human chondrocytes in late OA is changed in both fibrillated and intact cartilages without evidence of generalised chondrocyte hypertrophy

    Brew, CJ., Clegg, PD., Boot-Handford, R., Andrews, TE. & Hardingham, T., 2010, In : Annals Rheum Dis. 467

    Research output: Contribution to journalArticle

  8. Published

    Cartilage Repair Using Human Embryonic Stem Cell-Derived Chondroprogenitors.

    Cheng, A., Kapacee, Z., Peng, J., Lu, S., Lucas, R. J., Hardingham, T. E. & Kimber, S. J., 1 Oct 2014, In : Stem Cells Translational Medicine. p. 1-8 7 p., original article.

    Research output: Contribution to journalArticle

  9. Published

    Generating Cartilage Repair from Pluripotent Stem Cells

    Cheng, A., Hardingham, T. & Kimber, SJ., 2014, In : Tissue Engineering. Part B. Reviews . 20, 4, p. 257-266 9 p.

    Research output: Contribution to journalArticle

  10. Published

    Alternative Splicing in the Aggrecan G3 Domain Influences Binding Interactions with Tenascin-C and Other Extracellular Matrix Proteins

    Day, J. M., Olin, A. I., Murdoch, A. D., Canfield, A., Sasaki, T., Timpl, R., Hardingham, T. E. & Aspberg, A., 26 Mar 2004, In : Journal of Biological Chemistry. 279, 13, p. 12511-12518 7 p.

    Research output: Contribution to journalArticle

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