Prof Stuart Pickering-BrownPhD

Professor of Neurogenetics

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Publications

  1. 2016
  2. Published

    Pathological tau deposition in Motor Neurone Disease and Frontotemporal Lobar Degeneration associated with TDP-43 proteinopathy

    Behrouzi, R., Liu, X., Wu, D., Robinson, A., Tanaguchi-Watanabe, S., Rollinson, S., Shi, J., Tian, J., Hamdallah, H. H., Ealing, J., Richardson, A., Jones, M., Pickering-Brown, S., Davidson, Y., Strong, M. J., Hasegawa, M., Snowden, J. & Mann, D., 31 Mar 2016, In : Acta Neuropathologica Communications. 4, 33.

    Research output: Contribution to journalArticle

  3. Published

    Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

    Schott, J. M., Crutch, S. J., Carrasquillo, M. M., Uphill, J., Shakespeare, T. J., Ryan, N. S., Yong, K. X. X., Lehmann, M., Ertekin-Taner, N., Graff-Radford, N. R., Boeve, B. F., Murray, M. E., Khan, Q. U. A., Petersen, R. C., Dickson, D. W., Knopman, D. S., Rabinovici, G. D., Miller, B. L., Gonzalez, A. S., Gil-Néciga, E. & 24 others, Snowden, J. S., Harris, J., Pickering-Brown, S. M., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Pijnenburg, Y. A., Galasko, D., Sarazin, M., Dubois, B., Magnin, E., Galimberti, D., Scarpini, E., Cappa, S. F., Hodges, J. R., Halliday, G. M., Bartley, L., Carrillo, M. C., Bras, J. T., Hardy, J., Rossor, M. N., Collinge, J., Fox, N. C. & Mead, S., 15 Mar 2016, In : Alzheimer's and Dementia.

    Research output: Contribution to journalArticle

  4. Published

    Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies

    Kun-Rodrigues, C., Ross, O. A., Orme, T., Shepherd, C., Parkkinen, L., Darwent, L., Hernandez, D., Ansorge, O., Clark, L. N., Honig, L. S., Marder, K., Lemstra, A., Scheltens, P., van der Flier, W., Louwersheimer, E., Holstege, H., Rogaeva, E., St George-Hyslop, P., Londos, E., Zetterberg, H. & 44 others, Barber, I., Braae, A., Brown, K., Morgan, K., Maetzler, W., Berg, D., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Trojanowski, J. Q., Serrano, G. E., Beach, T. G., Clarimon, J., Lleó, A., Morenas-Rodríguez, E., Lesage, S., Galasko, D., Masliah, E., Santana, I., Diez, M., Pastor, P., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Stone, D. J., Pickering-Brown, S., Mann, D., Dickson, D. W., Halliday, G. M., Singleton, A., Guerreiro, R. & Bras, J., 2016, In : Neurobiology of Aging.

    Research output: Contribution to journalArticle

  5. 2015
  6. Published

    Neurodegeneration in Frontotemporal Lobar Degeneration and Motor Neurone Disease associated with expansions in C9orf72 is linked to TDP-43 pathology and not associated with aggregated forms of dipeptide repeat proteins.

    Davidson, Y., Robinson, A. C., Liu, X., Wu, D., Troakes, C., Rollinson, S., Masuda-Suzukake, M., Suzuki, G., Nonaka, T., Shi, J., Tian, J., Hamdalla, H., Ealing, J., Richardson, A., Jones, M., Pickering-Brown, S., Snowden, J. S., Hasegawa, M. & Mann, D. M. A., 5 Nov 2015, In : Neuropathology and Applied Neurobiology.

    Research output: Contribution to journalArticle

  7. Published

    Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.

    Guerreiro, R., Escott-Price, V., Darwent, L., Parkkinen, L., Ansorge, O., Hernandez, D. G., Nalls, M. A., Clark, L., Honig, L., Marder, K., van der Flier, W., Holstege, H., Louwersheimer, E., Lemstra, A., Scheltens, P., Rogaeva, E., St George-Hyslop, P., Londos, E., Zetterberg, H., Ortega-Cubero, S. & 27 others, Pastor, P., Ferman, T. J., Graff-Radford, N. R., Ross, O. A., Barber, I., Braae, A., Brown, K., Morgan, K., Maetzler, W., Berg, D., Troakes, C., Al-Sarraj, S., Lashley, T., Compta, Y., Revesz, T., Lees, A., Cairns, N. J., Halliday, G. M., Mann, D., Pickering-Brown, S., Powell, J., Lunnon, K., Lupton, M. K., Dickson, D., Hardy, J., Singleton, A. & Bras, J., 2 Nov 2015, In : Neurobiology of Aging.

    Research output: Contribution to journalArticle

  8. Published

    Is SIGMAR1 a confirmed FTD/MND gene?

    Pickering-Brown, S. & Hardy, J., Nov 2015, In : Brain. 138, Pt 11, p. e393

    Research output: Contribution to journalArticle

  9. Published

    Distinct clinical and pathological phenotypes in frontotemporal dementia associated with MAPT, PGRN and C9orf72 mutations.

    Snowden, J. S., Adams, J., Harris, J., Thompson, J. C., Rollinson, S., Richardson, A., Jones, M., Neary, D., Mann, D. M. & Pickering-Brown, S., 16 Oct 2015, In : Amyotrophic lateral sclerosis & frontotemporal degeneration. 16, 7-8, p. 497-505 9 p.

    Research output: Contribution to journalArticle

  10. Published

    p62/SQSTM1 analysis in frontotemporal lobar degeneration.

    Miller, L., Rollinson, S., Pickering-Brown, S., Callister, J. B., Young, K., Harris, J., Gerhard, A., Neary, D., Richardson, A., Snowden, J. & Mann, D. M., 10 Oct 2015, In : Neurobiology of Aging. 36, 3, p. 1603

    Research output: Contribution to journalArticle

  11. Published

    Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy

    Cooper-Knock, J., Higginbottom, A., Stopford, M. J., Highley, J. R., Ince, P. G., Wharton, S. B., Pickering-Brown, S., Kirby, J., Hautbergue, G. M. & Shaw, P. J., Jul 2015, In : Acta neuropathologica. 130, 1, p. 63-75 13 p.

    Research output: Contribution to journalArticle

  12. Published

    A novel Alzheimer disease locus located near the gene encoding tau protein.

    Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J-C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L-S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 406 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S-H., Boland, A., Becker, T., Kukull, W. A., van der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J-F., Hampel, H., Kamboh, M. I., de Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L-W., Karydas, A., Kauwe, J. S., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C-F., Lopez, O. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C-K., Yu, C-E., Yu, L., Au, R., Wolf, P. A., Beiser, A., Satizabal, C., Uitterlinden, A. G., Rivadeneira, F., Koudstaal, P. J., Longstreth Jr, W. T., Kuller, L. H., Lumley, T., Rice, K., Harris, T. B., Nalls, M., Marksteiner, J. J. M., Dal-Bianco, P., Töglhofer, A. M., Freudenberger, P., Ransmayr, G., Benke, T., Toeglhofer, A. M., Boerwinkle, E., Bressler, J., Fornage, M., Morón, F. J., Hernández, I., Roca, M. R., Mauleón, A., Alegret, M., Ramírez-Lorca, R., González-Perez, A., Alpérovitch, A., Alvarez, V., Barberger-Gateau, P., Bettens, K., Bossù, P., Brice, A., Bullido, M., Caffara, P., Clarimon, J., Combarros, O., Coto, E., Zampo, M. D., Delepine, M., Deniz Naranjo, M. C., Epelbaum, J., Fratiglioni, L., Galimberti, D., Graff, C., Hiltunen, M., Ingelsson, M., Keller, L., Lannfelt, L., Llèo, A., Mancuso, M., Mateo, I., Mecocci, P., Nacmias, B., Panza, F., Pilotto, A., Garcia, F. S., Scarpini, E., Seripa, D., Sleegers, K., Soininen, H., Sorbi, S., Spalletta, G., Wallon, D., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Psy, DC., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., Bussche, H. V. D., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K-H., Moebus, S., Klopp, N., Wichmann, H-E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., 17 Mar 2015, In : Molecular psychiatry.

    Research output: Contribution to journalArticle

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