Prof Simon ClarkB.Sc., D.Phil. (oxon)

Honorary Professor

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Publications

  1. 2019
  2. Published

    Loss-of-function mutations in the CFH gene affecting alternatively encoded Factor H-like 1 protein cause dominant early-onset macular drusen

    Taylor, R. L., Poulter, J., Downes, S., McKibbin, M., Khan, K. N., Inglehearn, C. F., Webster, A. R., Hardcastle, A. J., Michaelides, M., Bishop, P., Clark, S. & Black, G., 2019, In : Ophthalmology.

    Research output: Contribution to journalArticle

  3. Published

    Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes

    Porter, L. F., Saptarshi, N., Fang, Y., Rathi, S., den Hollander, A., de Jong, E., Clark, S., Bishop, P., Olsen, T., Liloglou, T., Chavali, V. & Paraoan, L., 2019, In : Clinical Epigenetics. 11, 6

    Research output: Contribution to journalArticle

  4. 2018
  5. Published

    C-reactive protein and pentraxin-3 binding of factor H-like protein 1 differs from complement factor H: implications for retinal inflammation

    Swinkels, M., Zhang, J. H., Tilakaratna, V., Black, G., Perveen, R., Mcharg, S., Inforzato, A., Day, A. & Clark, S., 2018, In : Scientific Reports.

    Research output: Contribution to journalArticle

  6. 2017
  7. Published

    Bruch's membrane compartmentalises complement regulation in the eye with implications for therapeutic design in age-related macular degeneration.

    Clark, S., Mcharg, S., Tilakaratna, V., Brace, N. & Bishop, P., 19 Dec 2017, In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  8. Published

    Complement factor H in host defense and immune evasion

    Inforzato, A., Day, A., Parente, R. & Clark, S., May 2017, In : Cellular and Molecular Life Sciences. 74, 9, p. 1605-1624 20 p.

    Research output: Contribution to journalArticle

  9. Published

    The eye as a complement dysregulation hotspot

    Clark, S. & Bishop, P., 2017, In : Seminars in Immunopathology.

    Research output: Contribution to journalArticle

  10. 2016
  11. Published

    Induction of chemokine secretion and monocyte migration by human choroidal melanocytes in response to pro-inflammatory cytokines

    Jehs, T., Faber, C., Udsen, M., Jager, M., Clark, S. & Nissen, M., 1 Dec 2016, In : Investigative ophthalmology & visual science. 57, 15

    Research output: Contribution to journalArticle

  12. Published

    Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

    Langford-Smith, A., Tilakaratna, V., Lythgoe, P. R., Clark, S., Bishop, P. N. & Day, A. J., Jan 2016, In : P L o S One. 11, 1, 16 p.

    Research output: Contribution to journalArticle

  13. Published

    Secondary photoreceptor degeneration: age-related macular degeneration

    Clark, S., 2016, Encyclopedia of the Eye.

    Research output: Contribution to specialist publicationArticle

  14. 2015
  15. Published

    Enrichment of Bruch’s membrane from human donor eyes

    McHarg, S., Brace, N., Bishop, P. N. & Clark, S. J., 16 Nov 2015, In : Journal of Visualized Experiments. 105

    Research output: Contribution to journalArticle

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