Prof Robert Clarke PhD

Professor

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Publications

  1. 2021
  2. E-pub ahead of print

    FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity

    Timbrell, S., Aglan, H., Cramer, A., Foden, P., Weaver, D., Pachter, J., Kilgallon, A., Clarke, R., Farnie, G. & Bundred, N., 28 May 2021, (E-pub ahead of print) In: NPJ Breast Cancer. p. 65 7.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Reciprocal Priming between Receptor Tyrosine Kinases at Recycling Endosomes Orchestrates Cellular Signalling Outputs

    Smith, M., Ferguson, H., Ferguson, J., Zindy, E., Kowalczyk, K., Kedward, T., Bates, C., Parsons, J., Watson, J., Chandler, S., Fullwood, P., Warwood, S., Clarke, R. & Francavilla, C., 28 Apr 2021, In: EMBO Journal. p. e107182 26 p., e107182.

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors

    Bach, K., Pensa, S., Zarocsinceva, M., Kania, K., Stockis, J., Pinaud, S., Lazarus, K. A., Shehata, M., Simões, B. M., Greenhalgh, A. R., Howell, S. J., Clarke, R. B., Caldas, C., Halim, T. Y. F., Marioni, J. C. & Khaled, W. T., 9 Mar 2021, In: Nature Communications. 12, 1

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

    PDXNET Consortium, EurOPDX Consortium, Alferez-Castro, D., Spence, K., Clarke, R. & et al., 7 Jan 2021, In: Nature Genetics. 53, 1, p. 86-99

    Research output: Contribution to journalArticlepeer-review

  6. 2020
  7. Published

    Preparation of a User-Defined Peptide Gel for Controlled 3D Culture Models of Cancer and Disease

    Clarke, R., 3 Dec 2020, In: Journal of Visualized Experiments. 166, p. e61710

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Increased expression of interleukin-1 receptor characterizes anti-estrogen resistant ALDH+ breast cancer stem cells

    Sarmiento Castro, A., Caamaño-Gutiérrez, E., Sims, A. H., Hull, N., James, M., Santiago-Gómez, A., Eyre, R., Clark, C., Brown, M. E., Brooks, M. D., Hayes, D. F., Wicha, M. S., Howell, S., Clarke, R. & M Simoes, B., 11 Aug 2020, In: Stem Cell Reports. 15, 2, p. 307-316 10 p.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer

    M Simoes, B., Santiago-Gómez, A., Chiodo, C., Moreira, T., Conole, D., Lovell, S., Alferez-Castro, D., Eyre, R., Spence, K., Sarmiento Castro, A., Kohler, B., Morisset, L., Lanzino, M., Ando, S., Marangoni, E., Sims, A. H., Tate, E., Howell, S. & Clarke, R., 18 Jun 2020, In: Oncogene. 39, 25, p. 4896–4908 13 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells

    Lazaro-Carrillo, A., Calero, M., Aires, A., L Cortajarena, A., Simões, B. M., Latorre, A., Somoza, Á., Clarke, R. B., Miranda, R. & Villanueva, A., 29 May 2020, In: Cancers. 12, 6

    Research output: Contribution to journalArticlepeer-review

  11. 2019
  12. Published

    The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling

    Yu, L., Xia, K., Gao, T., Chen, J., Zhang, Z., Sun, X., Simões, B. M., Eyre, R., Fan, Z., Guo, W. & Clarke, R. B., 1 Dec 2019, In: Molecular Cancer Research. 17, 12, p. 2383-2394 12 p.

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts

    Lefley, D. V., Howard, F., Arshad, F., Bradbury, S., Brown, H., Tulotta, C., Eyre, R., Alferez-Castro, D., Wilkinson, J. M., Holen, I., Clarke, R. B. & Ottewell, P. D., 29 Nov 2019, In: Breast cancer research : BCR. 21, 1, p. 130 21 p., 1.

    Research output: Contribution to journalArticlepeer-review

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