Prof Robert ClarkePhD

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Publications

  1. 2019
  2. E-pub ahead of print

    PAK4 regulates stemness and progression in endocrine resistant ERpositive metastatic breast cancer

    Santiago-Gómez, A., Kedward, T., M Simoes, B., Dragoni, I., NicAmhlaoibh, R., Trivier, E., Sabin, V., Gee, J. M., Sims, A. H., Howell, S. J. & Clarke, R. B., 20 May 2019, In : Cancer Letters. 11 p., 10.1016/j.canlet.2019.05.014.

    Research output: Contribution to journalArticle

  3. Published

    FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4

    McClements, L., Annett, S., Yakkundi, A., O'Rourke, M., Valentine, A., Moustafa, N., Alqudah, A., Simões, B. M., Furlong, F., Short, A., McIntosh, S. A., McCarthy, H. O., Clarke, R. B. & Robson, T., 2019, In : BMC Cancer. 19, 1, 351.

    Research output: Contribution to journalArticle

  4. Published
  5. 2018
  6. Published

    Ethnicity influences breast cancer stem cells' drug resistance

    Kamal, M., Nafie, E. H. O., Elsers, S., Alanwar, S., Ibrahim, R., Farag, F., Mlees, M., Simões, B. M., Spence, K., Santiago-Gómez, A., Salem, M. L. & Clarke, R. B., Jul 2018, In : Breast Journal. 24, 4, p. 701-703 3 p.

    Research output: Contribution to journalArticle

  7. Published

    Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP

    Piggott, L., Silva, A., Robinson, T., Santiago-Gómez, A., Simões, B. M., Becker, M., Fichtner, I., Andera, L., Young, P., Morris, C., Barrett-Lee, P., Alchami, F., Piva, M., Vivanco, M. DM., Clarke, R. B., Gee, J. & Clarkson, R., 15 May 2018, In : Clinical Cancer Research. 24, 10, p. 2452-2463 12 p.

    Research output: Contribution to journalArticle

  8. Published

    Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors

    M Simoes, B., Kholer, B., Clarke, R., Stringer, J., Novak Frazer, L., Young, K., Richardson, R., Zucchini, G., Armstrong, A. & Howell, S., 2018, In : Therapeutic Advances in Medical Oncology. 10

    Research output: Contribution to journalArticle

  9. Published

    The Role of Steroid Hormones in Breast and Effects on Cancer Stem Cells

    Alferez-Castro, D., M Simoes, B., Howell, S. & Clarke, R., 2018, In : Current Stem Cell Reports.

    Research output: Contribution to journalArticle

  10. 2017
  11. Published

    G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts

    De Francesco, E. M., Sotgia, F., Clarke, R. B., Lisanti, M. P. & Maggiolini, M., 14 Dec 2017, In : International Journal of Molecular Sciences. 18, 12

    Research output: Contribution to journalReview article

  12. Published

    GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment

    De Francesco, E., Sims, A. H., Maggiolini, M., Sotgia, F., Lisanti, M. P. & Clarke, R., 6 Dec 2017, In : Breast Cancer Research. 19, 1, p. 129 14 p.

    Research output: Contribution to journalArticle

  13. Published

    Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Byrne, A. T., Alférez, D. G., Amant, F., Annibali, D., Arribas, J., Biankin, A. V., Bruna, A., Budinská, E., Caldas, C., Chang, D. K., Clarke, R. B., Clevers, H., Coukos, G., Dangles-Marie, V., Eckhardt, S. G., Gonzalez-Suarez, E., Hermans, E., Hidalgo, M., Jarzabek, M. A., de Jong, S. & 22 othersJonkers, J., Kemper, K., Lanfrancone, L., Mælandsmo, G. M., Marangoni, E., Marine, J-C., Medico, E., Norum, J. H., Palmer, H. G., Peeper, D. S., Pelicci, P. G., Piris-Gimenez, A., Roman-Roman, S., Rueda, O. M., Seoane, J., Serra, V., Soucek, L., Vanhecke, D., Villanueva, A., Vinolo, E., Bertotti, A. & Trusolino, L., 2017, In : Nature Reviews. Cancer.

    Research output: Contribution to journalComment/debate

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