Dr Richard Unwin PhD

Senior Lecturer in Mass Spectrometry/Proteomics

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Phone: +44 (0)161 275 0235
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ORCID: 0000-0001-7955-9111
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Publications

1 - 10 out of 73Page size: 10
  1. 2020
  2. Published

    Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain

    Scholefield, M., Church, S. J., Xu, J., Robinson, A. C., Gardiner, N. J., Roncaroli, F., Hooper, N. M., Unwin, R. D. & Cooper, G. J. S., 29 Oct 2020, In: Metabolites. 10, 11

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3390/metabo10110438 10.3390/metabo10110438
  3. E-pub ahead of print

    Association of plasma trace element levels with neovascular age-related macular degeneration

    Heesterbeek, T. J., Rouhi-parkouhi, M., Church, S. J., Lechanteur, Y. T., Lorés-motta, L., Kouvatsos, N., Clark, S. J., Bishop, P. N., Hoyng, C. B., Den Hollander, A. I., Unwin, R. D. & Day, A. J., 21 Oct 2020, In: Experimental eye research. p. 108324

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.exer.2020.108324
  4. Published

    Epithelial cadherin regulates transition between the naïve and primed pluripotent states in mouse embryonic stem cells

    Sharaireh, A., Fitzpatrick, L. M., Ward, C., McKay, T. R. & Unwin, R., 1 Oct 2020, In: Stem Cells. 38, 10, p. 1292-1306

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/stem.3249
  5. Published

    Nano-scavengers for blood biomarker discovery in ovarian carcinoma

    Hadjidemetriou, M., Papafilippou, L., Unwin, R. D., Rogan, J., Clamp, A. & Kostarelos, K., 1 Oct 2020, In: Nano Today.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.nantod.2020.100901
  6. Published

    Cerebral deficiency of vitamin B5 (D-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease

    Xu, J., Patassini, S., Begley, P., Church, S., Waldvogel, H. J., Faull, R. L. M., Unwin, R. D. & Cooper, G. J. S., 30 Jun 2020, In: Biochemical and Biophysical Research Communications. 527, 3, p. 676-681 6 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.bbrc.2020.05.015
  7. E-pub ahead of print

    Intravitreal pharmacokinetic study of the anti-angiogenic glycoprotein opticin

    Del Amo, E. M., Griffiths, J. R., Klaska, I. P., Hoke, J., White, A., Aarons, L., Cooper, G. J. S., Bainbridge, J. W. B., Bishop, P. N. & Unwin, R. D., 21 May 2020, In: Molecular Pharmaceutics.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1021/acs.molpharmaceut.0c00151
  8. Published

    Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location

    Scholefield, M., Church, S. J., Xu, J., Kassab, S., Gardiner, N. J., Roncaroli, F., Hooper, N. M., Unwin, R. D. & Cooper, G. J. S., 6 May 2020, In: Metallomics : integrated biometal science.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1039/d0mt00048e
  9. Published

    The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination

    McGurk, K., Dagliati, A., Chiasserini, D., Lee, D., Plant, D., Baricevic-Jones, I., Kelsall, J., Eineman, R., Reed, R., Geary, B., Unwin, R., Nicolaou, A., Keavney, B., Barton, A., Whetton, A. & Geifman, N., 1 Apr 2020, In: Bioinformatics. 36, 7, p. 2217-2223 7 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1093/bioinformatics/btz898
  10. 2019
  11. Published

    Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigation

    Kassab, S., Begley, P., Church, S. J., Rotariu, S. M., Chevalier-riffard, C., Dowsey, A. W., Phillips, A. M., Zeef, L. A. H., Grayson, B., Neill, J. C., Cooper, G. J. S., Unwin, R. D. & Gardiner, N. J., 5 Aug 2019, In: Molecular Metabolism. 28, p. 107-119

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.molmet.2019.08.003
  12. Published

    Genetic risk of AMD at both the CFH and ARMS2/HTRA1 loci is associated with increased protease expression and activity in human Bruch’s membrane/inner choroid.

    Day, A., Bishop, P., Mcharg, S., Bayatti, N., Perveen, R., Black, G., Dowsey, A., Clark, S. & Unwin, R., 22 Jul 2019, In: Investigative ophthalmology & visual science. 60, 9, p. 2814 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

    DOI: https://iovs.arvojournals.org/article.aspx?articleid=2742846&resultClick=1
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Research Explorer downloads

186
Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy

Research output: Contribution to journal › Article › peer-review

105
Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia

Research output: Contribution to journal › Article › peer-review

99
Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice

Research output: Contribution to journal › Article › peer-review

72
Mass spectrometry-based proteomics reveals the distinct nature of the skin proteomes of photoaged compared to intrinsically aged skin

Research output: Contribution to journal › Article › peer-review

68
Graded perturbations of metabolism in multiple regions of human brain in Alzheimer’s disease. Snapshot of a pervasive metabolic disorder.

Research output: Contribution to journal › Article › peer-review

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