Prof Richard Marais

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Publications

  1. 2019
  2. E-pub ahead of print

    2-Aminomethylene-5-Sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth

    Smithen, D. A., Leung, L., Challinor, M., Lawrence, R., Tang, H., Niculescu-duvaz, D., Pearce, S. P., Mcleary, R., Lopes, F., Aljarah, M., Brown, M., Johnson, L., Thomson, G., Marais, R. & Springer, C., 20 Aug 2019, In : Journal of Medicinal Chemistry.

    Research output: Contribution to journalArticle

  3. Accepted/In press

    Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships

    Leung, L. M. H., Niculescu-Duvaz, D., Smithen, D., Lopes, F., Callens, C., Mcleary, R., Saturno, G., Davies, L., Aljarah, M., Brown, M., Lawrence, R., Challinor, M., Tang, H., Marais, R. & Springer, C., 9 May 2019, (Accepted/In press) In : Journal of Medicinal Chemistry.

    Research output: Contribution to journalArticle

  4. E-pub ahead of print

    Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA

    Tan, L., Sandhu, S., Lee, R. J., Li, J., Callahan, J., Ftouni, S., Dhomen, N., Middlehurst, P., Wallace, A., Raleigh, J., Hatzimihalis, A., Henderson, M. A., Shackleton, M., Haydon, A., Mar, V., Gyorki, D. E., Oudit, D., Dawson, M. A., Hicks, R. J., Lorigan, P. & 4 othersMcArthur, G. A., Marais, R., Wong, S. Q. & Dawson, S-J., 6 Feb 2019, In : Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 10.1093/annonc/mdz048.

    Research output: Contribution to journalArticle

  5. Published

    Utility of ctDNA to support patient selection for early phase clinical trials: The TARGET Study

    Rothwell, D., Ayub, M., Cook, N., Thistlethwaite, F., Carter, L., Dean, E., Smith, N., Villa, S., Dransfield, J., Dive, C., Clipson, A., White, D., Nessa, K., Ferdous, S., Howell, M., Gupta, A., Kilerci, B., Mohan, S., Frese, K., Gulati, S. & 23 othersMiller, C., Jordan, A., Eaton, H., Hickson, N., C, OB., Graham, D., Kelly, C., Aruketty, S., Metcalf, R., Chiramel, J., Tinsley, N., AJ, V., Kurup, R., Forest, H., Stevenson, J-A., Southam, S., Landers, D., Wallace, A., Marais, R., Hughes, A., Brady, G., Dive, C. & Krebs, M., 2019, In : Nature Medicine. 25, 5, p. 738-743 6 p.

    Research output: Contribution to journalArticle

  6. 2018
  7. E-pub ahead of print

    Ultraviolet radiation-induced DNA damage is prognostic for outcome in melanoma

    Trucco, L. D., Mundra, P. A., Hogan, K., Garcia-Martinez, P., Viros, A., Mandal, A. K., Macagno, N., Gaudy-Marqueste, C., Allan, D., Baenke, F., Cook, M., McManus, C., Sanchez-Laorden, B., Dhomen, N. & Marais, R., 3 Dec 2018, In : Nature Medicine.

    Research output: Contribution to journalArticle

  8. Published

    Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin

    Torres-ayuso, P., Sahoo, S., Ashton, G., An, E., Simms, N., Galvin, M., Leong, H. S., Frese, K. K., Simpson, K., Cook, N., Hughes, A., Miller, C. J., Marais, R., Dive, C., Krebs, M. G. & Brognard, J., 1 Dec 2018, In : Genomic Medicine. 3, 1

    Research output: Contribution to journalArticle

  9. Published

    Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations

    Kugel, C. H., Douglass, S. M., Webster, M. R., Kaur, A., Liu, Q., Yin, X., Weiss, S. A., Darvishian, F., Al-Rohil, R. N., Ndoye, A., Behera, R., Alicea, G. M., Ecker, B. L., Fane, M., Allegrezza, M. J., Svoronos, N., Kumar, V., Wang, D. Y., Somasundaram, R., Hu-Lieskovan, S. & 23 othersOzgun, A., Herlyn, M., Conejo-Garcia, J. R., Gabrilovich, D., Stone, E. L., Nowicki, T. S., Sosman, J., Rai, R., Carlino, M. S., Long, G. V., Marais, R., Ribas, A., Eroglu, Z., Davies, M. A., Schilling, B., Schadendorf, D., Xu, W., Amaravadi, R. K., Menzies, A. M., McQuade, J. L., Johnson, D. B., Osman, I. & Weeraratna, A. T., 1 Nov 2018, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 24, 21, p. 5347-5356 10 p.

    Research output: Contribution to journalArticle

  10. Published

    A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITFhigh/AXLlow melanoma

    Smith, M., Rana, S., Ferguson, J., Rowling, E., Flaherty, K. T., Wargo, J. A., Marais, R. & Wellbrock, C., 19 Oct 2018, In : Pigment cell & melanoma research.

    Research output: Contribution to journalArticle

  11. Published

    52OCirculating tumour DNA analysis predicts relapse following resection in stage II and III melanoma

    Tan, L., Sandhu, S. K., Lee, R., Li, J., Callahan, J., Raleigh, J., Hatzimihalis, A., Middlehurst, P., Henderson, M., Shackleton, M., Haydon, A., Gyorki, D., Oudit, D., Hicks, R. J., Lorigan, P., McArthur, G. A., Marais, R., Wong, S. Q. & Dawson, S-J., 1 Oct 2018, In : Annals of Oncology. 29, suppl_8

    Research output: Contribution to journalArticle

  12. Published

    Circulating tumour DNA analysis predicts relapse following resection in stage II and III melanoma

    Tan, L., Sandhu, S. K., Lee, R., Li, J., Callahan, J., Raleigh, J., Hatzimihalis, A., Middlehurst, P., Henderson, M., Shackleton, M., Haydon, A., Gyorki, D., Oudit, D., Hicks, R. J., Lorigan, P., McArthur, G. A., Marais, R., Wong, S. Q. & Dawson, S-J., Oct 2018, In : Annals of Oncology. 29

    Research output: Contribution to journalMeeting Abstract

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