We study biological clocks in ageing and age-related diseases
We utilize transgenic models, clinical samples, primary cells, circadian time series -omics, quantitative live imaging and machine learning algorithms to investigate the roles of circadian clocks in ageing and age-related diseases. Underpinning mechanisms identified will be targeted by pharmacological and other non-invasive approaches to slow down tissue degeneration and promote repair. We are also interested in a circadian medicine approach to tailor existing therapies according to the internal body clocks for better clinical outcomes.
Qing-Jun Meng is a Professor of Chronobiology and an Arthritis Research UK (ARUK; Versus Arthritis) Senior Research Fellow in the Faculty of Biology, Medicine and Health, the University of Manchester. He is the Theme Leader of the Chrono-Matrix research theme within the Wellcome Centre for Cell-Matrix Research. He is also the Director of Internationalisation in the School of Biological Sciences and was the co-founder and Academic Lead of the Biosciences International Summer School (BIO-SISS).
Qing-Jun (MD and PhD) started his post-doctoral training in 2003 at the University of Manchester on the molecular mechanisms and pharmacological resetting of the biological clocks. In 2009, Qing-Jun was awarded a MRC Career Development Award Fellowship on clocks, ageing and age-related diseases. In 2015, he was awarded an ARUK Senior Research Fellowship to continue his work into the roles of circadian clocks in health and disease of the musculoskeletal system.