Dr Philip Day PhD, FRSB, FRSC

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Publications

  1. 2020
  2. Accepted/In press

    MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

    Parkes, J., Thoma, A., Lightfoot, A. P., Day, P., Chinoy, H. & Lamb, J., 19 Mar 2020, (Accepted/In press) In : BMC Rheumatology.

    Research output: Contribution to journalArticle

  3. 2019
  4. Published

    The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data

    Wright Muelas, M., Mughal, F., O’Hagan, S., Day, P. J. & Kell, D. B., 29 Nov 2019, In : Scientific Reports. 9, 1, 17960.

    Research output: Contribution to journalArticle

  5. Published

    Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli

    Jindal, S., Yang, L., Day, P. & Kell, D., 22 Aug 2019, In : B M C Microbiology.

    Research output: Contribution to journalArticle

  6. Published

    GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries

    Currin, A., Kwok, J., Sadler, J. C., Bell, E. L., Swainston, N., Ababi, M., Day, P., Turner, N. J. & Kell, D. B., 21 Jun 2019, In : ACS Synthetic Biology. 8, 6, p. 1371-1378

    Research output: Contribution to journalArticle

  7. Published
  8. Published

    A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites

    Zhang, S., Sakuma, M., Deora, G. S., Levy, C., Klausing, A., Breda, C., Read, K. D., Ross, B. P., Wright Muelas, M., Day, P., O'Hagan, S., Kell, D., Schwarcz, R., Leys, D., Heyes, D., Giorgini, F. & Scrutton, N., 2019, In : Communications Biology.

    Research output: Contribution to journalArticle

  9. 2018
  10. Published

    Integrative analysis of rewired central metabolism in temozolomide resistant cells

    Immanuel, S. R. C., Ghanate, A. D., Parmar, D. S., Marriage, F., Panchagnula, V., Day, P. J. & Raghunathan, A., 8 Jan 2018, In : Biochemical and Biophysical Research Communications.

    Research output: Contribution to journalArticle

  11. Published
  12. 2017
  13. Published

    Using uncertainty to link and rank evidence from biomedical literature for model curation

    Zerva, C., Batista-Navarro, R. T., Day, P. & Ananiadou, S., 24 Jul 2017, In : Bioinformatics.

    Research output: Contribution to journalArticle

  14. Published

    CodonGenie: Optimised ambiguous codon design tools

    Swainston, N., Currin, A., Green, L., Breitling, R., Day, P. J. & Kell, D. B., 10 Jul 2017, In : PeerJ Computer Science. 2017, 7, e120.

    Research output: Contribution to journalArticle

  15. Published
  16. Published

    Computing exponentially faster: Implementing a non-deterministic universal Turing machine using DNA

    Currin, A., Korovin, K., Ababi, M., Roper, K., Kell, D. B., Day, P. J. & King, R. D., 1 Mar 2017, In : Journal of the Royal Society Interface. 14, 128, 20160990.

    Research output: Contribution to journalArticle

  17. Published
  18. Published

    Speedygenes: Exploiting an improved gene synthesis method for the efficient production of synthetic protein libraries for directed evolution

    Currin, A., Swainston, N., Day, P. J. & Kell, D. B., 2017, Synthetic DNA: Methods and Protocols. Hughes, R. A. (ed.). New York: Humana Press, Inc, p. 63-78 16 p. (Methods in Molecular Biology; vol. 1472).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  19. 2016
  20. Published

    Systematic Protein-Protein Interaction and Pathway Analyses in the Idiopathic Inflammatory Myopathies

    Parkes, J., Rothwell, S., Day, P., McHugh, N. J., Betteridge, Z. E., Cooper, R. G., Ollier, W., Chinoy, H. & Lamb, J., 7 Jul 2016, In : Arthritis Research and Therapy. 18, 156.

    Research output: Contribution to journalArticle

  21. Published

    Integrated electrowetting nanoinjector for single cell transfection

    Shekaramiz, E., Varadarajalu, G., Day, P. J. & Wickramasinghe, H. K., 4 Jul 2016, In : Scientific Reports. 6, 29051.

    Research output: Contribution to journalArticle

  22. Published

    Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB

    Haustead, D. J., Stevenson, A., Saxena, V., Marriage, F., Firth, M., Silla, R., Martin, L. W., Adcroft, K. F., Rea, S. M., Day, P., Melton, P., Wood, F. M. & Fear, M. W., 27 May 2016, In : Scientific Reports. 6, 26846.

    Research output: Contribution to journalArticle

  23. Published

    Computational fluid dynamics in the microcirculation and microfluidics: What role can the lattice Boltzmann method play?

    O'Connor, J., Day, P., Mandal, P. & Revell, A., 1 May 2016, In : Integrative Biology. 8, 5, p. 589-602 14 p.

    Research output: Contribution to journalArticle

  24. 2015
  25. E-pub ahead of print
  26. Published

    Expression of TEL-AML1 and EPA-PBX1 by real-time PCR in paediatric ALL in Baghdad

    Kadhom, AE., Adbul-Majeed, BA., AL-Hadad, SA. & Day, P., 2015, In : International Journal of Advanced Research. 2, 1, ISSN 2320-5407.

    Research output: Contribution to journalArticle

  27. Published

    Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

    Currin, A., Swainston, N., Day, P. & Kell, D. B., 2015, In : Chemical Society Reviews. 44, 5, p. 1172-1239 67 p.

    Research output: Contribution to journalArticle

  28. Published

    Systems medicine: the application of systems biology approaches for modern medical research and drug development

    Ayers, D. & Day, PJR., 2015, In : Molecular Biology International. 698169.

    Research output: Contribution to journalArticle

  29. Published

    The role of microRNA in the idiopathic inflammatory myopathies

    Parkes, J. E., Day, P., Chinoy, H. & Lamb, J. A., 2015, In : Current Opinion in Rheumatology. 27, 6, p. 608-615 7 p.

    Research output: Contribution to journalArticle

  30. 2014
  31. Published

    GeneGenie: optimized oligomer design for directed evolution

    Swainston, N., Currin, A., Day, P. & Kell, D., Jul 2014, In : Nucleic acids research. 42, Web Server issue, p. W395-W400

    Research output: Contribution to journalArticle

  32. Published

    Microfluidic channel-assisted screening of hematopoietic malignancies

    Mughal, F., Baldock, S. J., Karimiani, E. G., Telford, N., Goddard, N. J. & Day, P. J. R., Mar 2014, In : Genes Chromosomes and Cancer. 53, 3, p. 255-263 8 p.

    Research output: Contribution to journalArticle

  33. Published

    Single-cell analysis of K562 cells: an imatinib-resistant subpopulation is adherent and has upregulated expression of BCR-ABL mRNA and protein.

    Karimiani, E. G., Marriage, F., Merritt, A. J., Burthem, J., Byers, R. J. & Day, P., Mar 2014, In : Experimental Hematology. 42, 3, p. 183-191 8 p.

    Research output: Contribution to journalArticle

  34. Published

    SpeedyGenes: An improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution

    Day, P., Currin, A., Swainston, N., Day, P. J. & Kell, D. B., 2014, In : Protein Engineering, Design and Selection. 27, 9, p. 273-280 7 p.

    Research output: Contribution to journalArticle

  35. Published

    The IFN-λ genetic polymorphism association with the viral clearance induced by hepatitis c virus treatment in Pakistani patients

    Tipu, I., Marriage, F., Farooqi, Z-U-R., Platt, H., Athar, M. A., Day, P. & Short, A., 2014, In : Hepatitis Monthly. 14, 3, e15076.

    Research output: Contribution to journalArticle

  36. 2013
  37. Published

    Cytokeratin 15 marks basal epithelia in developing ureters and is upregulated in a subset of urothelial cell carcinomas

    Tai, G., Ranjzad, P., Marriage, F., Rehman, S., Denley, H., Dixon, J., Mitchell, K., Day, P. J. R. & Woolf, A. S., 18 Nov 2013, In : PLoS ONE. 8, 11, e81167.

    Research output: Contribution to journalArticle

  38. Published

    The need for transparency and good practices in the qPCR literature

    Bustin, S. A., Benes, V., Garson, J., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M. W., Shipley, G., Wittwer, C. T., Schjerling, P., Day, P. J., Abreu, M., Aguado, B., Beaulieu, J. F., Beckers, A., Bogaert, S., Browne, J. A., Carrasco-Ramiro, F. & 64 others, Ceelen, L., Ciborowski, K., Cornillie, P., Coulon, S., Cuypers, A., De Brouwer, S., De Ceuninck, L., De Craene, J., De Naeyer, H., De Spiegelaere, W., Deckers, K., Dheedene, A., Durinck, K., Ferreira-Teixeira, M., Fieuw, A., Gallup, J. M., Gonzalo-Flores, S., Goossens, K., Heindryckx, F., Herring, E., Hoenicka, H., Icardi, L., Jaggi, R., Javad, F., Karampelias, M., Kibenge, F., Kibenge, M., Kumps, C., Lambertz, I., Lammens, T., Markey, A., Messiaen, P., Mets, E., Morais, S., Mudarra-Rubio, A., Nakiwala, J., Nelis, H., Olsvik, P. A., Pérez-Novo, C., Plusquin, M., Remans, T., Rihani, A., Rodrigues-Santos, P., Rondou, P., Sanders, R., Schmidt-Bleek, K., Skovgaard, K., Smeets, K., Tabera, L., Toegel, S., Van Acker, T., Van Den Broeck, W., Van Der Meulen, J., Van Gele, M., Van Peer, G., Van Poucke, M., Van Roy, N., Vergult, S., Wauman, J., Tshuikina-Wiklander, M., Willems, E., Zaccara, S., Zeka, F. & Vandesompele, J., Nov 2013, In : Nature Methods. 10, 11, p. 1063-1067 4 p.

    Research output: Contribution to journalArticle

  39. Published

    Hyaluronic acid (HA) presentation as a tool to modulate and control the receptor-mediated uptake of HA-coated nanoparticles

    Almalik, A., Karimi, S., Ouasti, S., Donno, R., Wandrey, C., Day, P. J. & Tirelli, N., Jul 2013, In : Biomaterials. 34, 21, p. 5369-5380 11 p.

    Research output: Contribution to journalArticle

  40. Published

    Brief report: Shortened telomere length in patients with systemic lupus erythematosus

    Haque, S., Rakieh, C., Marriage, F., Ho, P., Gorodkin, R., Teh, L. S., Snowden, N., Day, P. J. R. & Bruce, I. N., May 2013, In : Arthritis Care & Research. 65, 5, p. 1319-1323 4 p.

    Research output: Contribution to journalArticle

  41. Published

    Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways

    Sun, S., Lee, D., Ho, A. S. W., Pu, J. K. S., Zhang, X. Q., Lee, N. P., Day, P. J. R., Lui, W. M., Fung, C. F. & Leung, G. K. K., May 2013, In : Neuro-Oncology. 15, 5, p. 562-577 15 p.

    Research output: Contribution to journalArticle

  42. Published

    Personalised treatment of haematological malignancies through systems medicine based on single molecules in single cells.

    Karimiani, EG. & Day, P., 27 Mar 2013, In : Integr Biol (Camb).

    Research output: Contribution to journalArticle

  43. Published

    Mathematical modelling of miRNA mediated BCR.ABL protein regulation in chronic myeloid leukaemia vis-a-vis therapeutic strategies

    Verma, M., Karimiani, E. G., Byers, R. J., Rehman, S., Westerhoff, H. V. & Day, P. J. R., Jan 2013, In : Integrative Biology (United Kingdom). 5, 3, p. 543-554 11 p.

    Research output: Contribution to journalArticle

  44. Published

    HA-Coated Chitosan Nanoparticles for CD44-Mediated Nucleic Acid Delivery

    Almalik, A., Day, P. J. & Tirelli, N., 2013, In : Macromolecular Bioscience. 13, 12, p. 1671-1680 10 p.

    Research output: Contribution to journalArticle

  45. Published

    Hyaluronic acid-coated chitosan nanoparticles: Molecular weight-dependent effects on morphology and hyaluronic acid presentation

    Almalik, A., Donno, R., Cadman, C. J., Cellesi, F., Day, P. J. & Tirelli, N., 2013, In : Journal of Controlled Release. 172, 3, p. 1142-1150 9 p.

    Research output: Contribution to journalArticle

  46. 2012
  47. Published

    Microdroplet Technology

    Day, PJR., Manz, A. & Zhang, Y., 1 Sep 2012, Microdroplet Technology: Principles and emerging applications in biology and chemistry. 1 ed. New York: Springer Nature, Vol. 1. p. 1-243 243 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  48. Published

    Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing

    Day, P., Sep 2012, In : Mol BioSyst. 8, 9, p. -2288 16 p.

    Research output: Contribution to journalArticle

  49. Published

    Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines

    Sun, S., Wong, T. S., Zhang, X. Q., Pu, J. K. S., Lee, N. P., Day, P. J. R., Ng, G. K. B., Lui, W. M. & Leung, G. K. K., Mar 2012, In : Journal of Neuro-Oncology. 107, 1, p. 89-100 11 p.

    Research output: Contribution to journalArticle

  50. Published

    Protein profiling of keloidal scar tissue

    Javad, F. & Day, PJ., Mar 2012, In : Arch Dermatol Res.

    Research output: Contribution to journalArticle

  51. Published

    Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children

    Irwin, A. D., Marriage, F., Mankhambo, L. A., Jeffers, G., Kolamunnage-Dona, R., Guiver, M., Denis, B., Molyneux, E. M., Molyneux, M. E., Day, P. J. & Carrol, E. D., 2012, In : BMC Medical Genomics. 5, 13.

    Research output: Contribution to journalArticle

  52. Published

    Understanding Dupuytren's disease using systems biology: A move away from reductionism

    Rehman, S., Day, P. J. R., Bayat, A. & Westerhoff, H. V., 2012, In : Frontiers in Physiology. 3, Article 316.

    Research output: Contribution to journalArticle

  53. 2011
  54. Published

    PCR-based diagnostics put to the test

    Ed, R. JP. & Day, P., Nov 2011, In : GEN. 31, 18, p. 56-58 3 p.

    Research output: Contribution to journalArticle

  55. Published

    Dupuytren's: A systems biology disease

    Rehman, S., Goodacre, R., Day, P. J., Bayat, A. & Westerhoff, H. V., 12 Sep 2011, In : Arthritis Res Ther. 13, 5, 238.

    Research output: Contribution to journalArticle

  56. Published

    Human Papilloma Virus strain detection utilising custom-designed oligonucleotide microarrays

    Ayers, D., Platt, M., Javad, F. & Day, P. J. R., 2011, In : Methods in Molecular Biology. 688, p. 75-95 20 p.

    Research output: Contribution to journalArticle

  57. 2010
  58. Published

    The influence of immunosuppressive drugs on vascular endothelial growth factor production in relation to VEGF -1154 G and -2578 C genotypes

    Mohammadi, M. & Day, P. J. R., Dec 2010, In : Iranian Journal of Immunology. 7, 4, p. 217-225 8 p.

    Research output: Contribution to journalArticle

  59. Published

    Convergent evolution to an aptamer observed in small populations on DNA microarrays

    Rowe, W., Platt, M., Wedge, D. C., Day, P. J. R., Kell, D. B. & Knowles, J. D., Sep 2010, In : Physical Biology. 7, 3, 036007.

    Research output: Contribution to journalArticle

  60. Published

    Proteomics of hepatocellular carcinoma: Serum vimentin as a surrogate marker for small tumors (≤2 cm)

    Sun, S., Poon, R. T. P., Lee, N. P., Yeung, C., Chan, K. L., Ng, I. O. L., Day, P. J. R. & Luk, J. M., 5 Apr 2010, In : Journal of Proteome Research. 9, 4, p. 1923-1930 7 p.

    Research output: Contribution to journalArticle

  61. Published

    High-throughput droplet PCR

    Day, P., Markey, A. L., Mohr, S. & Day, P. J. R., Apr 2010, In : Methods. 50, 4, p. 277-281 4 p.

    Research output: Contribution to journalArticle

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