Dr Pawel PaszekPhD, FHEA


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  1. 2017
  2. Published

    Anti-inflammatory effects of infliximab in mice are independent of TNFα neutralization

    Assas, B. M., Levison, S., Little, M., England, H., Battrick, L., Bagnall, J., Mclaughlin, J., Paszek, P., Else, K. & Pennock, J. Feb 2017 In : Clinical and Experimental Immunology. 187, 2

    Research output: Research - peer-reviewArticle

  3. Published

    Integration of kinase and calcium signaling at 1 the level of chromatin underlies inducible gene activation in T cells

    Brignall, R., Cauchy, P., Bevington, S. L. B., Gorman, B., Pisco, A. O., Bagnall, J., Boddington, C., Rowe, W., England, H., Rich, K., Schmidt, L., Dyer, N. P., Travis, M., Ott, S., Jackson, D., Cockerill, P. N. & Paszek, P. 2017 In : Journal of Immunology.

    Research output: Research - peer-reviewArticle

  4. 2016
  5. Published

    Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

    Phillips, N., Manning, C., Pettini, T., Biga, V., Marinopoulou, E., Stanley, P., Boyd, J., Bagnall, J., Paszek, P., Spiller, D., White, M., Goodfellow, M., Galla, T., Rattray, M. & Papalopulu, N. 4 Oct 2016 In : eLife. 5, e16118

    Research output: Research - peer-reviewArticle

  6. Published

    Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

    Daniels, M. J. D. , Rivers-Auty, J. , Schilling, T. , Spencer, N. G. , Watremez, W. , Fasolino, V. , Booth, S. J. , White, C. S. , Baldwin, A. G. , Freeman, S. , Wong, R. , Latta, C. , Yu, S. , Jackson, J. , Fischer, N. , Koziel, V. , Pillot, T. , Bagnall, J. , Allan, S. M. , Paszek, P. & 5 others Galea, J., Harte, M. K., Eder, C., Lawrence, C. B. & Brough, D. 11 Aug 2016 In : Nature communications. 7, p. 12504 12504

    Research output: Research - peer-reviewArticle

  7. Published

    Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

    Adamson, A., Boddington, C., Downton, P., Rowe, W., Bagnall, J., Lam, C., Maya-Mendoza, A., Schmidt, L., Harper, C. V., Spiller, D., Rand, D. A., Jackson, D., White, M. R. H. & Paszek, P. 6 Jul 2016 In : Nature communications. 7, 12057

    Research output: Research - peer-reviewArticle

  8. Published

    Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

    Martín-Sánchez, F., Diamond, C., Zeitler, M., Gomez-Sanchez, A., Baroja-Mazo, A., Bagnall, J., Spiller, D., White, M., Daniels, M., Mortellaro, A., Peñalver, M., Paszek, P., Steringer, J. P., Nickel, W., Brough, D. & Pelegrin, P. Jul 2016 In : Cell Death & Differentiation. 23, 7, p. 1219-1231 13 p.

    Research output: Research - peer-reviewArticle

  9. Published

    Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

    Ankers, J. M., Awais, R., Jones, N. A., Boyd, J., Ryan, S., Adamson, A. D., Harper, C. V., Bridge, L., Spiller, D. G., Jackson, D. A., Paszek, P., Sée, V. & White, M. R. 17 May 2016 In : eLife. 5

    Research output: Research - peer-reviewArticle

  10. Published

    Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

    Diamond, C., Bagnall, J., Spiller, D., White, M., Mortellaro, A., Paszek, P. & Brough, D. 2016 NLR proteins: Methods and protocols. Di Virgilio, F. & Pablo, P. (eds.). SpringerLink, p. 75-88 13 p. (Methods in Molecular Biology; vol. 1417)

    Research output: Research - peer-reviewChapter

  11. 2015
  12. Published

    Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

    Bagnall, J., Boddington, C., Boyd, J., Brignall, R., Rowe, W., Jones, N. A., Schmidt, L., Spiller, D. G., White, M. R. H. & Paszek, P. 8 Jun 2015 In : Integrative biology : quantitative biosciences from nano to macro. 7, 6, p. 713-725 12 p.

    Research output: Research - peer-reviewArticle

  13. Published

    A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system.

    West, S., Bridge, L. J., White, M. R. H., Paszek, P. & Biktashev, V. N. Feb 2015 In : Journal of Mathematical Biology. 70, 3, p. 591-620 29 p.

    Research output: Research - peer-reviewArticle

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Research output: Research - peer-reviewArticle