Prof Paul BishopPhD, FRCOphth

Professor of Ophthalmology & Matrix Biol

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Publications

  1. Published

    A novel peripherin/RDS mutation resulting in a retinal dystrophy with phenotypic variation

    Kalyanasundaram, T. S., Black, G. C., O'Sullivan, J. & Bishop, P. N., Jan 2009, In : Eye. 23, 1, p. 237-239 2 p.

    Research output: Contribution to journalArticle

  2. Published

    Acute visual loss after thioridazine overdose [4]

    Anderton, L. & Bishop, P., 2001, In : The American journal of psychiatry. 158, 5, p. 818

    Research output: Contribution to journalArticle

  3. Published

    Acute visual loss following thioridazine overdose

    Anderton, L. & Bishop, PN., 2001, In : The American journal of psychiatry. 158

    Research output: Contribution to journalArticle

  4. Published

    Adult vitreous structure and postnatal changes

    Le Goff, M. M. & Bishop, P. N., 2008, In : Eye. 22, 10, p. 1214-1222 8 p.

    Research output: Contribution to journalArticle

  5. Published

    Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

    Langford-Smith, A., Tilakaratna, V., Lythgoe, P. R., Clark, S., Bishop, P. N. & Day, A. J., Jan 2016, In : P L o S One. 11, 1, 16 p.

    Research output: Contribution to journalArticle

  6. Published

    Age-dependent changes in heparan sulfate in human Bruch's membrane: Implications for age-related macular degeneration

    Keenan, T. D. L., Pickford, C. E., Holley, R. J., Clark, S. J., Lin, W., Dowsey, A. W., Merry, C. L., Day, A. J. & Bishop, P. N., 29 Jul 2014, In : Investigative Ophthalmology and Visual Science. 55, 8, p. 5370-5379 9 p.

    Research output: Contribution to journalArticle

  7. Published

    Age-dependent changes in the basal retinovitreous adhesion

    Wang, J., McLeod, D., Henson, D. B. & Bishop, P. N., 1 May 2003, In : Investigative Ophthalmology and Visual Science. 44, 5, p. 1793-1800 7 p.

    Research output: Contribution to journalArticle

  8. Published

    Age-related macular degeneration and the role of the complement system.

    Mcharg, S., Clark, S. J., Day, A. J. & Bishop, P. N., Sep 2015, In : Molecular immunology. 67, 1, p. 43-50 7 p.

    Research output: Contribution to journalArticle

  9. Published

    Age-related macular degeneration: The importance of family history as a risk factor

    Bishop, P., Shahid, H., Khan, J. C., Cipriani, V., Sepp, T., Matharu, B. K., Bunce, C., Harding, S. P., Clayton, D. G., Moore, A. T. & Yates, J. R. W., Mar 2012, In : British Journal Of Ophthalmology. 96, 3, p. 427-431 4 p.

    Research output: Contribution to journalArticle

  10. Published

    An immune dot-blot test for the diagnosis of ocular infection with Chlamydia trachomatis

    Bishop, P. N., Tullo, A. B., Killough, R. & Richmond, S. J., 1991, In : Eye. 5, 3, p. 305-308 3 p.

    Research output: Contribution to journalArticle

  11. Published

    Assessment of Proteins Associated With Complement Activation and Inflammation in Maculae of Human Donors Homozygous Risk at Chromosome 1 CFH-to-F13B.

    Keenan, T. D. L., Toso, M., Pappas, C., Nichols, L., Bishop, P. N. & Hageman, G. S., Jul 2015, In : Investigative ophthalmology & visual science. 56, 8

    Research output: Contribution to journalArticle

  12. Published

    Author's reply: To PMID 24888710

    Dawes, P., Dickinson, C., Emsley, R., Bishop, P., Cruickshanks, K. J., Edmondson-Jones, M., McCormack, A., Fortnum, H., Norman, P., Munro, K. & Moore, D., 23 Dec 2014, In : Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists). 35, 1, p. 107-8 2 p.

    Research output: Contribution to journalArticle

  13. Published

    Automated retinal image quality assessment on the UK Biobank dataset for epidemiological studies

    UK Biobank Eye and Vision Consortium, 1 Apr 2016, In : Computers in Biology and Medicine. 71, p. 67-76 10 p.

    Research output: Contribution to journalArticle

  14. Published

    Axial structure of the heterotypic collagen fibrils of vitreous humour and cartilage

    Mcleod, D., Bos, K. J., Holmes, D. F., Kadler, K. E., McLeod, D., Morris, N. P. & Bishop, P. N., 9 Mar 2001, In : Journal of molecular biology. 306, 5, p. 1011-1022 11 p.

    Research output: Contribution to journalArticle

  15. Published

    Bilateral subfoveal choroidal neovascularization in Turner's syndrome: Coincidence or consequence?

    Beatty, S., Black, G., Rhatigan, M. & Bishop, P., Oct 1999, In : Canadian Journal of Ophthalmology. 34, 6, p. 346-348 2 p.

    Research output: Contribution to journalArticle

  16. Published

    Bruch's membrane compartmentalises complement regulation in the eye with implications for therapeutic design in age-related macular degeneration.

    Clark, S., Mcharg, S., Tilakaratna, V., Brace, N. & Bishop, P., 19 Dec 2017, In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  17. Published

    Characterisation of the metabolome of ocular tissues and postmortem changes in the rat retina

    Tan, S. Z., Mullard, G., Hollywood, K., Dunn, W. B. & Bishop, P., Aug 2016, In : Experimental eye research. 149, p. 8-15 8 p.

    Research output: Contribution to journalArticle

  18. Published

    Characterization of Opticin and Evidence of Stable Dimerization in Solution

    Le Goff, M. M., Hindson, V. J., Jowitt, T. A., Scott, P. G. & Bishop, P. N., 14 Nov 2003, In : Journal of Biological Chemistry. 278, 46, p. 45280-45287 7 p.

    Research output: Contribution to journalArticle

  19. Published

    Characterization of opticin digestion by proteases involved in osteoarthritis development.

    Tío, L., Martel-Pelletier, J., Pelletier, J-P., Bishop, P. N., Roughley, P., Farran, A., Benito, P. & Monfort, J., Mar 2014, In : Joint, bone, spine : revue du rhumatisme. 81, 2, p. 137-141 4 p.

    Research output: Contribution to journalArticle

  20. Published

    Class III SLRP agonists for the reduction of blood vessel formation

    Bishop, P. N., 15 Apr 2008, Patent No. US7358224

    Research output: Patent

  21. Published

    Collagen fibril organisation in mammalian vitreous by freeze etch/rotary shadowing electron microscopy

    Bos, K. J., Holmes, D. F., Meadows, R. S., Kadler, K. E., McLeod, D. & Bishop, P. N., 2001, In : Micron. 32, 3, p. 301-306 5 p.

    Research output: Contribution to journalArticle

  22. Published

    Collagen fibril organization in mammalian vitreous by freeze etching/rotary shadowing electon microscopy

    Bos, KJ., Holmes, DF., Meadows, RS., Kadler, KE., Mcleod, D. & Bishop, PN., 2001, In : Micron. 32

    Research output: Contribution to journalArticle

  23. Published

    Complement factor H and age-related macular degeneration: The role of glycosaminoglycan recognition in disease pathology

    Clark, S. J., Bishop, P. N. & Day, A. J., Oct 2010, In : Biochemical Society Transactions. 38, 5, p. 1342-1348 6 p.

    Research output: Contribution to journalArticle

  24. Published

    Complementing the sugar code: role of GAGs and sialic acid in complement regulation

    Langford-Smith, A., Day, A. J., Bishop, P. N. & Clark, S. J., 2015, In : Frontiers in Immunology. 6, 6, 25.

    Research output: Contribution to journalArticle

  25. Published

    Concentration of various trace elements in the rat retina and their distribution in different structures

    Ugarte, M., Grime, G. W., Lord, G., Geraki, K., Collingwood, J. F., Finnegan, M. E., Farnfield, H., Merchant, M., Bailey, M. J., Ward, N. I., Foster, P. J., Bishop, P. N., Osborne, N. N., Grime, GW., Collingwood, JF., Finnegan, ME., Bailey, MJ., Foster, PJ. & Bishop, PN., Dec 2012, In : Metallomics. 4, 12, p. 1245-1254 9 p.

    Research output: Contribution to journalArticle

  26. Published

    Crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class I small leucine-rich repeat proteoglycans

    Scott, P. G., Dodd, C. M., Bergmann, E. M., Sheehan, J. K. & Bishop, P. N., 12 May 2006, In : Journal of Biological Chemistry. 281, 19, p. 13324-13332 8 p.

    Research output: Contribution to journalArticle

  27. Published

    Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan

    Scott, P. G., McEwan, P. A., Dodd, C. M., Bergmann, E. M., Bishop, P. N. & Bella, J., 2 Nov 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 44, p. 15633-15638 5 p.

    Research output: Contribution to journalArticle

  28. Published

    Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease.

    Church, S. J., Begley, P., Kureishy, N., McHarg, S., Bishop, P. N., Bechtold, D. A., Unwin, R. D. & Cooper, G. J. S., 8 May 2015, In : Biochemical and biophysical research communications. 460, 3, p. 549-554

    Research output: Contribution to journalArticle

  29. Published

    Development of vitreous and composition of the vitreous gel.

    Bishop, PN., 2003, Pathologie du vitre.: Raport annuel de la societe francaise d’ophtalmologie pour l’annee. Brasseur, G. (ed.). Elsevier BV

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. Published

    Discovery and Functional Analysis of a Retinitis Pigmentosa Gene, C2ORF71

    Nishimura, D. Y., Baye, L. M., Perveen, R., Searby, C. C., Avila-Fernandez, A., Pereiro, I., Ayuso, C., Valverde, D., Bishop, P. N., Manson, F. D. C., Urquhart, J., Stone, E. M., Slusarski, D. C., Black, G. C. M. & Sheffield, V. C., 14 May 2010, In : American Journal of Human Genetics. 86, 5, p. 686-695 9 p.

    Research output: Contribution to journalArticle

  31. Published

    Disorders of the vitreous

    Bishop, PN., 2008, Pathobiology of Ocular Disease: A Dynamic Approach. 3 ed. New York: Marcel Dekker Inc.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  32. Published

    Efficacy and safety of glycosidic enzymes for improved gene delivery to the retina following intravitreal injection in mice

    Cehajic-Kapetanovic, J., Milosavljevic, N., Bedford, R., Lucas, R. & Bishop, P., 2017, In : Molecular Therapy - Methods & Clinical Development.

    Research output: Contribution to journalArticle

  33. Published

    Enrichment of Bruch’s membrane from human donor eyes

    McHarg, S., Brace, N., Bishop, P. N. & Clark, S. J., 16 Nov 2015, In : Journal of Visualized Experiments. 105

    Research output: Contribution to journalArticle

  34. Published

    Erratum to: A new strategy for MS/MS data acquisition applying multiple data dependent experiments on Orbitrap mass spectrometers in non-targeted metabolomic applications

    Mullard, G., Allwood, J. W., Weber, J., Brown, R. J. M., Begley, P., Hollywood, K. A., Jones, M., Unwin, R., Bishop, P., Cooper, G. & Dunn, W. B., 2015, In : Metabolomics. 11, p. 1081 1 p.

    Research output: Contribution to journalArticle

  35. Published

    Extraction and characterisation of the intact form of bovine vitreous type IX collagen

    Bishop, P., McLeod, D. & Ayad, S., 29 May 1992, In : Biochemical and Biophysical Research Communications. 185, 1, p. 392-397 5 p.

    Research output: Contribution to journalArticle

  36. Published

    Extraction and characterization of the tissue forms of collagen types II and IX from bovine vitreous

    Bishop, P. N., Crossman, M. V., McLeod, D. & Ayad, S., 1994, In : Biochemical Journal. 299, 2, p. 497-505 8 p.

    Research output: Contribution to journalArticle

  37. Published

    Extraction of the intact form of type IX collagen from mammalian vitreous

    Bishop, P. N., McLeod, D. & Ayad, S., 1991, In : Biochemical Society Transactions. 19, 4, p. 351

    Research output: Contribution to journalArticle

  38. Published

    Fibulin 5 forms a compact dimer in physiological solutions

    Jones, R. P. O., Wang, M. C., Jowitt, T. A., Ridley, C., Mellody, K. T., Howard, M., Wang, T., Bishop, P. N., Lotery, A. J., Kielty, C. M., Baldock, C. & Trump, D., 18 Sep 2009, In : Journal of Biological Chemistry. 284, 38, p. 25938-25943 5 p.

    Research output: Contribution to journalArticle

  39. Published

    Focus on Molecules: Opticin

    Le Goff, M. M. & Bishop, P. N., Sep 2007, In : Experimental eye research. 85, 3, p. 303-304 1 p.

    Research output: Contribution to journalArticle

  40. Published

    Fragmentation of structural components of mammalian vitreous by an endogenous matrix metalloproteinase

    Brown, DJ., Bishop, PN., Hamdi, H. & Kenney, MC., 1996, In : Current Eye Research. 15

    Research output: Contribution to journalArticle

  41. Published

    Fundamentals and Principles of Ophthalmology

    Bishop, PN., Mayne, R., Morris, RE. & McLeod, D., 2001, American Academy and Ophthalmology Basic and Clinical Science Course, Section 2. American Association of Ophthalmologists , p. 348-354

    Research output: Chapter in Book/Report/Conference proceedingChapter

  42. Published

    Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration

    Ansari, M., Mckeigue, P. M., Skerka, C., Hayward, C., Rudan, I., Vitart, V., Polasek, O., Armbrecht, A. M., Yates, J. R. W., Vatavuk, Z., Bencic, G., Kolcic, I., Oostra, B. A., Van Duijn, C. M., Campbell, S., Stanton, C. M., Huffman, J., Shu, X., Khan, J. C., Shahid, H. & 11 others, Harding, S. P., Bishop, P. N., Deary Ian J., I. J., Moore, A. T., Dhillon, B., Rudan, P., Zipfel, P. F., Sim, R. B., Hastie, N. D., Campbell, H. & Wright, A. F., Dec 2013, In : Human Molecular Genetics. 22, 23, p. 4857-4869 12 p., ddt336.

    Research output: Contribution to journalArticle

  43. Published

    Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

    CREAM, 23andMe Research Team, UK Biobank Eye and Vision Consortium, Aslam, T. M. & Bishop, P. N., 1 Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

    Research output: Contribution to journalArticle

  44. Published

    Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3

    Cipriani, V., Leung, H. T., Plagnol, V., Bunce, C., Khan, J. C., Shahid, H., Moore, A. T., Harding, S. P., Bishop, P. N., Hayward, C., Campbell, S., Armbrecht, A. M., Dhillon, B., Deary, I. J., Campbell, H., Dunlop, M., Dominiczak, A. F., Mann, S. S., Jenkins, S. A., Webster, A. R. & 13 others, Bird, A. C., Lathrop, M., Zelenika, D., Souied, E. H., Sahel, J. A., Léveillard, T., Cree, A. J., Gibson, J., Ennis, S., Lotery, A. J., Wright, A. F., Clayton, D. G. & Yates, J. R. W., Sep 2012, In : Human Molecular Genetics. 21, 18, p. 4138-4150 12 p., dds225.

    Research output: Contribution to journalArticle

  45. Published

    Glycan localization within the human interphotoreceptor matrix and photoreceptor inner and outer segments

    Bishop, P. N., Boulton, M., McLeod, D. & Stoddart, R. W., 1993, In : Glycobiology. 3, 4, p. 403-412 9 p.

    Research output: Contribution to journalArticle

  46. Published

    Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2

    Cehajic-Kapetanovic, J., le Goff, M. M., Allen, A., Lucas, R. J. & Bishop, P. N., 2011, In : Molecular vision. 17, p. 1771-1783 12 p.

    Research output: Contribution to journalArticle

  47. Published

    Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix

    Mcleod, D., Reardon, A. J., Le Goff, M. L., Briggs, M. D., McLeod, D., Sheehan, J. K., Thornton, D. J. & Bishop, P. N., 21 Jan 2000, In : Journal of Biological Chemistry. 275, 3, p. 2123-2129 6 p.

    Research output: Contribution to journalArticle

  48. Published

    Identification of alternatively spliced variants of type II procollagen in vitreous

    Bishop, P. N., Reardon, A. J., McLeod, D. & Ayad, S., 1994, In : Biochemical and Biophysical Research Communications. 203, 1, p. 289-295 6 p.

    Research output: Contribution to journalArticle

  49. Published

    Identification of factor H-like protein 1 as the predominant complement regulator on Bruch’s membrane: implications for age-related macular degeneration

    Clark, S. J., Schmidt, C. Q., White, A. M., Hakobyan, S., Morgan, B. P. & Bishop, P. N., 15 Nov 2014, In : Journal of Immunology. 193, p. 4962-4970 8 p.

    Research output: Contribution to journalArticle

  50. Published

    Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: a novel target for MMP-13 in osteoarthritis

    Monfort, J., Tardif, G., Roughley, P., Reboul, P., Boileau, C., Bishop, P. N., Pelletier, J. P. & Martel-Pelletier, J., Jul 2008, In : Osteoarthritis and Cartilage. 16, 7, p. 749-755 6 p.

    Research output: Contribution to journalArticle

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