Prof Nicholas Turner

Professor of Chemical Biology

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Publications

  1. 2019
  2. Published

    Electrocatalytic Volleyball: Rapid Nanoconfined Nicotinamide Cycling for Organic Synthesis in Electrode Pores

    Megarity, C. F., Siritanaratkul, B., Heath, R. S., Wan, L., Morello, G., FitzPatrick, S. R., Booth, R. L., Sills, A. J., Robertson, A. W., Warner, J. H., Turner, N. J. & Armstrong, F. A., 14 Feb 2019, In : Angewandte Chemie - International Edition.

    Research output: Contribution to journalArticle

  3. Published

    Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades

    Ramsden, J. I., Heath, R. S., Derrington, S. R., Montgomery, S. L., Mangas-Sanchez, J., Mulholland, K. R. & Turner, N. J., 23 Jan 2019, In : Journal of the American Chemical Society.

    Research output: Contribution to journalArticle

  4. Published

    A generic platform for the immobilisation of engineered biocatalysts

    Thompson, M. P., Derrington, S. R., Heath, R. S., Porter, J. L., Mangas-Sanchez, J., Devine, P. N., Truppo, M. D. & Turner, N. J., 18 Jan 2019, In : Tetrahedron. 75, 3, p. 327-334 8 p.

    Research output: Contribution to journalArticle

  5. Published

    Regio- and Enantio-selective Chemo-enzymatic C-H-lactonization of Decanoic Acid to (S)-δ-Decalactone.

    Manning, J., Tavanti, M., Porter, J., Kress, N., De Visser, S., Turner, N. & Flitsch, S., 2019, In : Angewandte Chemie.

    Research output: Contribution to journalArticle

  6. 2018
  7. Published

    Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement

    Zawodny, W., Montgomery, S. L., Marshall, J. R., Finnigan, J. D., Turner, N. J. & Clayden, J., 26 Dec 2018, In : Journal of the American Chemical Society. 140, 51, p. 17872-17877 6 p.

    Research output: Contribution to journalArticle

  8. Published

    An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols

    Heath, R. S., Birmingham, W. R., Thompson, M. P., Taglieber, A., Daviet, L. & Turner, N. J., 10 Dec 2018, In : CHEMBIOCHEM.

    Research output: Contribution to journalArticle

  9. Published

    A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases

    Sharma, M., Mangas-Sanchez, J., France, S. P., Aleku, G. A., Montgomery, S. L., Ramsden, J. I., Turner, N. J. & Grogan, G., 7 Dec 2018, In : ACS Catalysis. 8, 12, p. 11534-11541 8 p.

    Research output: Contribution to journalArticle

  10. Published

    Concurrent Biocatalytic Oxidation and C–C Bond Formation via Gold Catalysis: One-Pot Alkynylation of N-Alkyl Tetrahydroisoquinolines

    Odachowski, M., Greaney, M. F. & Turner, N. J., 2 Nov 2018, In : ACS Catalysis. 8, 11, p. 10032-10035

    Research output: Contribution to journalArticle

  11. Published

    Monoamine Oxidase (MAO-N) Whole Cell Biocatalyzed Aromatization of 1,2,5,6-Tetrahydropyridines into Pyridines

    Toscani, A., Risi, C., Black, G. W., Brown, N. L., Shaaban, A., Turner, N. J. & Castagnolo, D., 7 Sep 2018, In : ACS Catalysis. 8, 9, p. 8781-8787 6 p.

    Research output: Contribution to journalArticle

  12. Published

    Highly Productive Oxidative Biocatalysis in Continuous Flow by Enhancing the Aqueous Equilibrium Solubility of Oxygen

    Chapman, M. R., Cosgrove, S. C., Turner, N. J., Kapur, N. & Blacker, A. J., 13 Aug 2018, In : Angewandte Chemie - International Edition. 57, 33, p. 10535-10539 5 p.

    Research output: Contribution to journalArticle

  13. Published

    Selenzyme: Enzyme selection tool for pathway design

    Carbonell, P., Wong, J., Swainston, N., Takano, E., Turner, N., Scrutton, N., Kell, D., Breitling, R. & Faulon, J-L., 15 Jun 2018, In : Bioinformatics. 34, 12

    Research output: Contribution to journalArticle

  14. Published

    Synergistic Chemo/Biocatalytic Synthesis of Alkaloidal Tetrahydroquinolines

    Cosgrove, S. C., Hussain, S., Turner, N. J. & Marsden, S. P., 1 Jun 2018, In : ACS Catalysis. 8, 6, p. 5570-5573 4 p.

    Research output: Contribution to journalArticle

  15. Published

    The crystal structure of P450-TT heme-domain provides the first structural insights into the versatile class VII P450s

    Tavanti, M., Porter, J. L., Levy, C. W., Gómez Castellanos, J. R., Flitsch, S. L. & Turner, N. J., 17 May 2018, In : Biochemical and Biophysical Research Communications. 501, 4, p. 846-850 5 p.

    Research output: Contribution to journalArticle

  16. Published

    A Single Enzyme Oxidative "cascade" via a Dual-Functional Galactose Oxidase

    Birmingham, W. R. & Turner, N. J., 4 May 2018, In : ACS Catalysis. 8, 5, p. 4025-4032 8 p.

    Research output: Contribution to journalArticle

  17. Published

    Biocatalytic conversion of cyclic ketones bearing α-quaternary stereocenters to lactones in an enantioselective radical approach to medium-sized carbocycles

    Morrill, C., Jensen, C., Just-Baringo, X., Grogan, G., Turner, N. & Procter, D., 26 Mar 2018, In : Angewandte Chemie - International Edition. 57, 14, p. 3692-3696 4 p.

    Research output: Contribution to journalArticle

  18. Published

    Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis

    Weise, N., Parmeggiani, F., Ahmed, S. & Turner, N., 25 Jan 2018, In : Topics in Catalysis.

    Research output: Contribution to journalArticle

  19. Accepted/In press

    Imine Reductases, Reductive Aminases, and Amine Oxidases for the Synthesis of Chiral Amines: Discovery, Characterization, and Synthetic Applications

    Cosgrove, S. C., Brzezniak, A., France, S. P., Ramsden, J. I., Mangas-Sanchez, J., Montgomery, S. L., Heath, R. S. & Turner, N. J., 1 Jan 2018, (Accepted/In press) In : Methods in Enzymology.

    Research output: Contribution to journalArticle

  20. Published

    An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

    Carbonell, P., Jervis, A., Robinson, C., Yan, C., Dunstan, M., Swainston, N., Vinaixa, M., Hollywood, K., Currin, A., Rattray, N., Taylor, S., Spiess, R., Sung, R., Williams, A. R., Fellows, D., Stanford, N., Mulherin, P., Le Feuvre, R., Barran, P., Goodacre, R. & 9 othersTurner, N., Goble, C., Guoqiang Chen, G., Kell, D., Micklefield, J., Breitling, R., Takano, E., Faulon, J-L. & Scrutton, N., 2018, In : Communications Biology. 1, 66.

    Research output: Contribution to journalArticle

  21. Published

    Bio-derived Production of Cinnamyl Alcohol via a Three Step Biocatalytic Cascade and Metabolic Engineering

    Klumbys, E., Zebec, Z., Weise, N., Turner, N. & Scrutton, N., 2018, In : Green Chemistry.

    Research output: Contribution to journalArticle

  22. Published

    Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction

    Galman, J. L., Slabu, I., Parmeggiani, F. & Turner, N. J., 2018, In : Chemical Communications. 54, 80, p. 11316-11319 4 p.

    Research output: Contribution to journalArticle

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