Prof Nicholas Turner

Professor of Chemical Biology

Full contact details
View graph of relations

Publications

  1. Article › Research › Peer-reviewed
  2. Published

    A biocatalytic cascade for the amination of unfunctionalised cycloalkanes

    Tavanti, M., Mangas-Sanchez, J., Montgomery, S. L., Thompson, M. P. & Turner, N. J., 14 Dec 2017, In : Organic and Biomolecular Chemistry. 15, 46, p. 9790-9793 4 p.

    Research output: Contribution to journalArticle

  3. Published

    A fast and sensitive assay for measuring the activity and enantioselectivity of transaminases

    Hopwood, J., Truppo, M. D., Turner, N. J. & Lloyd, R. C., 14 Jan 2011, In : Chemical Communications. 47, 2, p. 773-775 2 p.

    Research output: Contribution to journalArticle

  4. Published

    A generic platform for the immobilisation of engineered biocatalysts

    Thompson, M. P., Derrington, S. R., Heath, R. S., Porter, J. L., Mangas-Sanchez, J., Devine, P. N., Truppo, M. D. & Turner, N. J., 18 Jan 2019, In : Tetrahedron. 75, 3, p. 327-334 8 p.

    Research output: Contribution to journalArticle

  5. Published

    A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases

    Sharma, M., Mangas-Sanchez, J., France, S. P., Aleku, G. A., Montgomery, S. L., Ramsden, J. I., Turner, N. J. & Grogan, G., 7 Dec 2018, In : ACS Catalysis. 8, 12, p. 11534-11541 8 p.

    Research output: Contribution to journalArticle

  6. Published

    A novel hyaluronan-based biomaterial (Hyaff-11®) as a scaffold for endothelial cells in tissue engineered vascular grafts

    Turner, N. J., Kielty, C. M., Walker, M. G., Canfield, A. E. & Turner, N., Dec 2004, In : Biomaterials. 25, 28, p. 5955-5964 9 p.

    Research output: Contribution to journalArticle

  7. Published
  8. Published

    A reductive aminase from Aspergillus oryzae

    Aleku, G., France, S., Man, H., Mangas-Sanchez, J., Montgomery, S., Sharma, M., Leipold, F., Hussain, S., Grogan, G. & Turner, N., 2017, In : Nature Chemistry.

    Research output: Contribution to journalArticle

  9. Published

    A regio- and stereoselective ω-transaminase/monoamine oxidase cascade for the synthesis of chiral 2,5-disubstituted pyrrolidines

    O'Reilly, E., Iglesias, C., Ghislieri, D., Hopwood, J., Galman, J. L., Lloyd, R. C. & Turner, N. J., 24 Feb 2014, In : Angewandte Chemie - International Edition. 53, 9, p. 2447-2450 3 p.

    Research output: Contribution to journalArticle

  10. Published

    A Single Enzyme Oxidative "cascade" via a Dual-Functional Galactose Oxidase

    Birmingham, W. R. & Turner, N. J., 4 May 2018, In : ACS Catalysis. 8, 5, p. 4025-4032 8 p.

    Research output: Contribution to journalArticle

  11. Published

    A stereospecific solid-phase screening assay for colonies expressing both (R)- and (S)-selective ω-aminotransferases

    Willies, S., Galman, J., Slabu, I. & Turner, N., 11 Jan 2016, In : Royal Society of London. Proceedings A. Mathematical, Physical and Engineering Sciences.

    Research output: Contribution to journalArticle

  12. Published

    A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A

    Bailey, K. R., Ellis, A. J., Reiss, R., Snape, T. J. & Turner, N. J., 2007, In : Chemical Communications. 35, p. 3640-3642 2 p.

    Research output: Contribution to journalArticle

  13. Published

    A Versatile Chemo-Enzymatic Route to Enantiomerically Pure β-Branched α-Amino Acids

    Roff, G. J., Lloyd, R. C. & Turner, N. J., 7 Apr 2004, In : Journal of the American Chemical Society. 126, 13, p. 4098-4099 1 p.

    Research output: Contribution to journalArticle

  14. Published

    Absolute quantification of uric acid in human urine using surface enhanced Raman scattering with the standard addition method

    Westley, C., Xu, Y., Thilaganathan, B., Carnell, A. J., Turner, N. & Goodacre, R., 21 Feb 2017, In : Analytical Chemistry. 89, 4, p. 2472–2477 6 p.

    Research output: Contribution to journalArticle

  15. Published

    Achieving optimal SERS through enhanced experimental design

    Turner, N., Fisk, H., Westley, C. & Goodacre, R., 16 Dec 2016, In : Journal of Raman Spectroscopy. 47, 1, p. 59-66

    Research output: Contribution to journalArticle

  16. Published

    Active site diversification of P450cam with indole generates catalysts for benzylic oxidation reactions

    Flitsch, S., Kelly, P., Eichler, A., Herter, S., Kranz, D. C. & Turner, N., Sep 2015, In : Beilstein Journal of Organic Chemistry. 11, p. 1713-1720

    Research output: Contribution to journalArticle

  17. Published

    Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides

    Wood, A., Weise, N., Frampton, J. D., Dunstan, M., Hollas, M., Derrington, S., Lloyd, R. C., Quaglia, D., Parmeggiani, F., Leys, D., Turner, N. & Flitsch, S., 13 Nov 2017, In : Angewandte Chemie. 56, 46, p. 14498-14501 4 p.

    Research output: Contribution to journalArticle

  18. Published

    Ammonia lyases and aminomutases as biocatalysts for the synthesis of α-amino and β-amino acids

    Turner, N. J., Apr 2011, In : Current Opinion in Chemical Biology. 15, 2, p. 234-240 6 p.

    Research output: Contribution to journalArticle

  19. Published

    An (R)-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines

    Hussain, S., Leipold, F., Man, H., Wells, E., France, S. P., Mulholland, K. R., Grogan, G. & Turner, N., 21 Jan 2015, In : ChemCatChem (Online).

    Research output: Contribution to journalArticle

  20. Published

    An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

    Carbonell, P., Jervis, A., Robinson, C., Yan, C., Dunstan, M., Swainston, N., Vinaixa, M., Hollywood, K., Currin, A., Rattray, N., Taylor, S., Spiess, R., Sung, R., Williams, A. R., Fellows, D., Stanford, N., Mulherin, P., Le Feuvre, R., Barran, P., Goodacre, R. & 9 othersTurner, N., Goble, C., Guoqiang Chen, G., Kell, D., Micklefield, J., Breitling, R., Takano, E., Faulon, J-L. & Scrutton, N., 2018, In : Communications Biology. 1, 66.

    Research output: Contribution to journalArticle

  21. Published

    An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols

    Heath, R. S., Birmingham, W. R., Thompson, M. P., Taglieber, A., Daviet, L. & Turner, N. J., 10 Dec 2018, In : CHEMBIOCHEM.

    Research output: Contribution to journalArticle

  22. Published
  23. Published

    Artificial concurrent catalytic processes involving enzymes

    Turner, N. & Köhler, V., 2015, In : Chemical Communications. 51, 3, p. 450-464

    Research output: Contribution to journalArticle

  24. Published

    Asymmetric Synthesis of Tetracyclic Pyrroloindolines and Constrained Tryptamines by a Switchable Cascade Reaction

    de Graaff, C., Bensch, L., Boersma, S. J., Cioc, R. C., Van Lint, M. J., Janssen, E., Turner, N., Orru, R. V. A. & Ruijter, E., 2015, In : Angewandte Chemie - International Edition. 54, 47, p. 14133-14136

    Research output: Contribution to journalArticle

  25. Published

    Bacterial Anabaena variabilis phenylalanine ammonia lyase: A biocatalyst with broad substrate specificity

    Lovelock, S. & Turner, N., 2014, In : Bioorganic and Medicinal Chemistry. 22, 20, p. 5555-5557

    Research output: Contribution to journalArticle

  26. Published

    Biocatalysis

    Turner, N. J., Aug 2012, In : Catalysis Science and Technology. 2, 8, p. 1523

    Research output: Contribution to journalArticle

  27. Published

    Biocatalysis - A gateway to industrial biotechnology

    Fessner, W. D., Turner, N. J. & Wang, M. X., Sep 2011, In : Advanced synthesis & catalysis. 353, 13, p. 2189-2190 1 p.

    Research output: Contribution to journalArticle

  28. Published

    Biocatalytic approaches to a key building block for the anti-thrombotic agent ticagrelor

    Hugentobler, K. G., Sharif, H., Rasparini, M., Heath, R. S. & Turner, N. J., 2016, In : Organic and Biomolecular Chemistry. 14, 34, p. 8064-8067 4 p.

    Research output: Contribution to journalArticle

  29. Published

    Biocatalytic approaches to the synthesis of enantiomerically pure chiral amines

    Ghislieri, D. & Turner, N., 2014, In : Topics in Catalysis. 57, 5, p. 284-300

    Research output: Contribution to journalArticle

  30. Published

    Biocatalytic conversion of cyclic ketones bearing α-quaternary stereocenters to lactones in an enantioselective radical approach to medium-sized carbocycles

    Morrill, C., Jensen, C., Just-Baringo, X., Grogan, G., Turner, N. & Procter, D., 26 Mar 2018, In : Angewandte Chemie - International Edition. 57, 14, p. 3692-3696 4 p.

    Research output: Contribution to journalArticle

  31. Published

    Biocatalytic desymmetrization of an atropisomer with both an enantioselective oxidase and ketoreductases

    Yuan, B., Page, A., Worrall, C. P., Escalettes, F., Willies, S. C., McDouall, J. J. W., Turner, N. J. & Clayden, J., 17 Sep 2010, In : Angewandte Chemie - International Edition. 49, 39, p. 7010-7013 3 p.

    Research output: Contribution to journalArticle

  32. Published

    Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts

    Staniland, S., Adams, R., Mcdouall, J., Maffucci, I., Contini, A., Grainger, D., Turner, N. & Clayden, J., 26 Aug 2016, In : Angewandte Chemie. 55, 36, p. 10755-10759 5 p.

    Research output: Contribution to journalArticle

  33. Published

    Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades

    Ramsden, J. I., Heath, R. S., Derrington, S. R., Montgomery, S. L., Mangas-Sanchez, J., Mulholland, K. R. & Turner, N. J., 23 Jan 2019, In : Journal of the American Chemical Society.

    Research output: Contribution to journalArticle

  34. Published

    Biocatalytic retrosynthesis: Redesigning synthetic routes to high-value chemicals

    Turner, N. & Green, A., 14 Sep 2016, In : Perspectives in Science.

    Research output: Contribution to journalArticle

  35. Published

    Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines

    France, S. P., Aleku, G. A., Sharma, M., Mangas-Sanchez, J., Howard, R. M., Steflik, J., Kumar, R., Adams, R. W., Slabu, I., Crook, R., Grogan, G., Wallace, T. W. & Turner, N. J., 2017, In : Angewandte Chemie - International Edition. 56, 49, p. 15589-15593 5 p.

    Research output: Contribution to journalArticle

  36. Published

    Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases

    Galman, J., Slabu, I., Weise, N., Iglesias, C., Parmeggiani, F., Lloyd, R. C. & Turner, N., 2017, In : Green Chemistry.

    Research output: Contribution to journalArticle

  37. Published

    Bio-derived Production of Cinnamyl Alcohol via a Three Step Biocatalytic Cascade and Metabolic Engineering

    Klumbys, E., Zebec, Z., Weise, N., Turner, N. & Scrutton, N., 2018, In : Green Chemistry.

    Research output: Contribution to journalArticle

  38. Published

    Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction

    Galman, J. L., Slabu, I., Parmeggiani, F. & Turner, N. J., 2018, In : Chemical Communications. 54, 80, p. 11316-11319 4 p.

    Research output: Contribution to journalArticle

  39. Published

    Biosynthesis and Characterization of Copper Nanoparticles Using Shewanella oneidensis: Application for Click Chemistry

    Kimber, R., Lewis, E. A., Parmeggiani, F., Smith, K., Bagshaw, H., Starborg, T., Joshi, N., Figueroa, A. I., Van der Laan, G., Cibin, G., Gianolio, D., Haigh, S., Pattrick, R. A. D., Turner, N. & Lloyd, J., 2018, In : Small.

    Research output: Contribution to journalArticle

  40. Published

    Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities

    Kalim Akhtara, M., Turner, N. J. & Jones, P. R., 2 Jan 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. 87-92 5 p.

    Research output: Contribution to journalArticle

  41. Published

    Case Studies Illustrating a Science and Risk-Based Approach to Ensuring Drug Quality When Using Enzymes in the Manufacture of Active Pharmaceuticals Ingredients for Oral Dosage Form

    Turner, N., Wells, A., Wong, J. W., Michels, P. C., Fandrick, K., Finch, G. L., Goswami, A., Lee, H., Mix, S., Moody, T., Pang, L., Entwistle, D. A., Sato, R. K. & Watson, T. J., 9 Feb 2016, In : Organic Process Research & Development. 20, 3, p. 3298-3306

    Research output: Contribution to journalArticle

  42. Published

    Catalytic bio-chemo and bio-bio tandem oxidation reactions for amide and carboxylic acid synthesis

    Bechi, B., Herter, S., McKenna, S., Riley, C., Leimkühler, S., Turner, N. J. & Carnell, A. J., 18 Aug 2014, In : Green Chemistry. 16, p. 4524-4529 5 p., C4GC01321B.

    Research output: Contribution to journalArticle

  43. Published

    Characterisation of CYP102A25 from B. marmarensis and CYP102A26 from P. halophilus: P450 homologues of BM3 with preference towards hydroxylation of medium chain fatty acids

    Porter, J., Manning, J., Sabatini, S., Tavanti, M., Turner, N. & Flitsch, S., 2017, In : ChemBioChem: a European journal of chemical biology .

    Research output: Contribution to journalArticle

  44. Published

    Characterization of a new acidic NAD+-dependent formate dehydrogenase from thermophilic fungus Chaetomium thermophilum

    Turner, N., Özgün, G., Karagüler, N. G. & Turunen, O., 2015, In : Journal of Molecular Catalysis B: Enzymatic. 122, p. 212-217

    Research output: Contribution to journalArticle

  45. Published

    Chemo-biocatalytic one-pot two-step conversion of cyclic amine to lactam using whole cell monoamine oxidase

    Zajkoska, P., Cárdenas-Fernández, M., Lye, G. J., Rosenberg, M., Turner, N. J. & Rebroš, M., 1 Jul 2017, In : Journal of Chemical Technology and Biotechnology. 92, 7, p. 1558-1565 8 p.

    Research output: Contribution to journalArticle

  46. Published
  47. Published

    Chemo-enzymatic synthesis of pyrazines and pyrroles

    Turner, N. J., Green, A. & Xu, J., 2018, In : Angewandte Chemie International Edition.

    Research output: Contribution to journalArticle

  48. Published

    Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement

    Zawodny, W., Montgomery, S. L., Marshall, J. R., Finnigan, J. D., Turner, N. J. & Clayden, J., 26 Dec 2018, In : Journal of the American Chemical Society. 140, 51, p. 17872-17877 6 p.

    Research output: Contribution to journalArticle

  49. Published

    Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope

    Robin, A., Köhler, V., Jones, A., Ali, A., Kelly, P. P., O'Reilly, E., Turner, N. J. & Flitsch, S. L., 2 Nov 2011, In : Beilstein Journal of Organic Chemistry. 7, p. 1494-1498 4 p., 7.

    Research output: Contribution to journalArticle

  50. Published

    Chiral Amine Synthesis Using ω-Transaminases: An Amine Donor Which Displaces Equilibria and Enables High-Throughput Screening

    Green, A., Turner, N. & O'Reilly, E., 19 Aug 2014, In : Angewandte Chemie (International Edition). 53, 40, p. 10714-10717

    Research output: Contribution to journalArticle

  51. Published

    Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris

    Markošová, K., Camattari, A., Rosenberg, M., Glieder, A., Turner, N. J. & Rebroš, M., 2017, In : Biotechnology Letters. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  52. Published

    Cloning, expression and characterisation of P450-Hal1 (CYP116B62) from Halomonas sp. NCIMB 172: A self-sufficient P450 with high expression and diverse substrate scope

    Porter, J., Sabatini, S., Manning, J., Tavanti, M., Galman, J., Turner, N. & Flitsch, S., 2018, In : Enzyme and Microbial Technology.

    Research output: Contribution to journalArticle

  53. Published

    Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of variants of monoamine oxidase from Aspergillus niger

    Atkin, K. E., Reiss, R., Turner, N. J., Brzozowski, A. M. & Grogan, G., 2008, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 64, 3, p. 182-185 3 p.

    Research output: Contribution to journalArticle

  54. Published

    Combined Imine Reductase and Amine Oxidase Catalyzed Deracemization of Nitrogen Heterocycles

    Heath, R. S., Pontini, M., Hussain, S. & Turner, N. J., 7 Jan 2016, In : ChemCatChem. 8, 1, p. 117-120 4 p.

    Research output: Contribution to journalArticle

  55. Published

    Comparison of a Batch and Flow Approach for the Lipase-Catalyzed Resolution of a Cyclopropanecarboxylate Ester, A Key Building Block for the Synthesis of Ticagrelor

    Hugentobler, K. G., Rasparini, M., Thompson, L. A., Jolley, K. E., Blacker, A. J. & Turner, N. J., 17 Feb 2017, In : Organic Process Research and Development. 21, 2, p. 195-199 5 p.

    Research output: Contribution to journalArticle

  56. Published

    Concurrent Biocatalytic Oxidation and C–C Bond Formation via Gold Catalysis: One-Pot Alkynylation of N-Alkyl Tetrahydroisoquinolines

    Odachowski, M., Greaney, M. F. & Turner, N. J., 2 Nov 2018, In : ACS Catalysis. 8, 11, p. 10032-10035

    Research output: Contribution to journalArticle

  57. Published

    Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathways

    Flitsch, S., France, S., Hepworth, L. & Turner, N., 2017, In : ACS Catalysis. p. 710-724 14 p.

    Research output: Contribution to journalArticle

  58. Published

    Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades.

    Mutti, FG., Knaus, T., Scrutton, NS., Breuer, M. & Turner, N., 2015, In : Science. 349, p. 1525-1529 4 p.

    Research output: Contribution to journalArticle

  59. Published

    Cytochromes P450 as useful biocatalysts: Addressing the limitations

    O'Reilly, E., Köhler, V., Flitsch, S. L. & Turner, N. J., 7 Mar 2011, In : Chemical Communications. 47, 9, p. 2490-2501 11 p.

    Research output: Contribution to journalArticle

  60. Published

    De Novo Enzyme Cascades in Whole Cells for the Synthesis of Chiral Cyclic Amines.

    Hepworth, L., France, S., Hussain, S., Both, P., Turner, N. & Flitsch, S., 2017, In : ACS Catalysis.

    Research output: Contribution to journalArticle

  61. Published

    Deracemisation methods

    Turner, N. J., Apr 2010, In : Current Opinion in Chemical Biology. 14, 2, p. 115-121 6 p.

    Research output: Contribution to journalArticle

  62. Published

    Deracemisation of benzylisoquinoline alkaloids employing monoamine oxidase variants

    Schrittwieser, J., Groenendaal, B., Willies, S. C., Ghislieri, D., Rowles, I., Resch, V., Sattler, J. H., Fischereder, E-M., Grischek, B., Lienhart, W-D., Turner, N. & Kroutil, W., 2014, In : Catalysis Science and Technology. 4, 10, p. 3657-3664

    Research output: Contribution to journalArticle

  63. Published

    Deracemization by simultaneous bio-oxidative kinetic resolution and stereoinversion

    Schrittwieser, J., Groenendaal, B., Resch, V., Ghislieri, D., Wallner, S., Fischereder, E-M., Fuchs, E., Grischek, B., Sattler, J. H., Macheroux, P., Turner, N. & Kroutil, W., 2014, In : Angewandte Chemie - International Edition. 53, 14, p. 3731-3734

    Research output: Contribution to journalArticle

  64. Published

    Deracemization of α-methylbenzylamine using an enzyme obtained by in vitro evolution

    Alexeeva, M., Enright, A., Dawson, M. J., Mahmoudian, M. & Turner, N. J., 2 Sep 2002, In : Angewandte Chemie - International Edition. 41, 17, p. 3177-3180 3 p.

    Research output: Contribution to journalArticle

  65. Published

    Design and Synthesis of Conformationally Constrained Cyclophilin Inhibitors Showing a Cyclosporin-A Phenotype in C. elegans

    Dunsmore, C. J., Malone, K. J., Bailey, K. R., Wear, M. A., Florance, H., Shirran, S., Barran, P. E., Page, A. P., Walkinshaw, M. D. & Turner, N. J., 21 Mar 2011, In : ChemBioChem: a European journal of chemical biology . 12, 5, p. 802-810 8 p.

    Research output: Contribution to journalArticle

  66. Published

    Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis

    Nowicki, M. W., Tulloch, L. B., Worralll, L., McNae, I. W., Hannaert, V., Michels, P. A. M., Fothergill-Gilmore, L. A., Walkinshaw, M. D. & Turner, N. J., 1 May 2008, In : Bioorganic and Medicinal Chemistry. 16, 9, p. 5050-5061 11 p.

    Research output: Contribution to journalArticle

  67. Published

    Development of a high-throughput screening method for racemase activity and its application to the identification of alanine racemase variants with activity towards l-arginine

    Willies, S. C., White, J. L. & Turner, N. J., 16 Sep 2012, In : Tetrahedron. 68, 37, p. 7564-7567 3 p.

    Research output: Contribution to journalArticle

  68. Published

    Development of a Solid Phase Array Assay for the Screening of Galactose Oxidase Activity and for Fast Identification of Inhibitors

    Weissenborn, M. J., Debecker, D. P., Golten, S., Linclau, B., Turner, N. & Flitsch, S., 2017, In : Protein and Peptide Letters. 24, 8, p. 742-746 5 p.

    Research output: Contribution to journalArticle

  69. Published

    Development of an R-selective amine oxidase with broad substrate specificity and high enantioselectivity

    Heath, R., Pontini, M., Turner, N. & Bechi, B., 2014, In : ChemCatChem. 6, 4, p. 996-1002

    Research output: Contribution to journalArticle

  70. Published

    Direct Alkylation of Amines with Primary and Secondary Alcohols through Biocatalytic Hydrogen Borrowing

    Montgomery, S. L., Mangas-Sanchez, J., Thompson, M. P., Aleku, G. A., Dominguez, B. & Turner, N. J., 16 Aug 2017, In : Angewandte Chemie (International ed. in English). 56, 35, p. 10491-10494 4 p.

    Research output: Contribution to journalArticle

  71. Published

    Directed Evolution of an Amine Oxidase Possessing both Broad Substrate Specificity and High Enantioselectivity

    Carr, R., Alexeeva, M., Enright, A., Eve, T. S. C., Dawson, M. J. & Turner, N. J., 13 Oct 2003, In : Angewandte Chemie - International Edition. 42, 39, p. 4807-4810 3 p.

    Research output: Contribution to journalArticle

  72. Published

    Directed evolution of galactose oxidase: Generation of enantioselective secondary alcohol oxidases

    Escalettes, F. & Turner, N. J., 14 Apr 2008, In : ChemBioChem: a European journal of chemical biology . 9, 6, p. 857-860 3 p.

    Research output: Contribution to journalArticle

  73. Published

    Directed evolution of the enzyme monoamine oxidase (mao-n): Highly efficient chemo-enzymatic deracemisation of the alkaloid (±)-crispinea

    Rowles, I., Malone, K. J., Etchells, L. L., Willies, S. C. & Turner, N. J., Sep 2012, In : ChemCatChem. 4, 9, p. 1259-1261 2 p.

    Research output: Contribution to journalArticle

  74. Published

    Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis

    Weise, N., Parmeggiani, F., Ahmed, S. & Turner, N., 25 Jan 2018, In : Topics in Catalysis.

    Research output: Contribution to journalArticle

  75. Published

    Discovery of a new metal and NAD+-dependent formate dehydrogenase from Clostridium ljungdahlii

    Çakar, M. M., Mangas-Sanchez, J., Birmingham, W. R., Turner, N. J. & Binay, B., 2018, In : Preparative Biochemistry and Biotechnology. 48, 4, p. 327-334 8 p.

    Research output: Contribution to journalArticle

  76. Published

    Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

    Slabu, I., Galman, J. L., Lloyd, R. C. & Turner, N. J., 1 Dec 2017, In : ACS Catalysis. 7, 12, p. 8263-8284 22 p.

    Research output: Contribution to journalArticle

  77. Published

    Electrocatalytic Volleyball: Rapid Nanoconfined Nicotinamide Cycling for Organic Synthesis in Electrode Pores

    Megarity, C. F., Siritanaratkul, B., Heath, R. S., Wan, L., Morello, G., FitzPatrick, S. R., Booth, R. L., Sills, A. J., Robertson, A. W., Warner, J. H., Turner, N. J. & Armstrong, F. A., 14 Feb 2019, In : Angewandte Chemie - International Edition.

    Research output: Contribution to journalArticle

  78. Published

    Enantioselective Benzylic Hydroxylation Catalysed by P450 Monooxygenases: Characterisation of a P450cam Mutant Library and Molecular Modelling

    Eichler, A., Gricman, Ł., Herter, S., Kelly, P., Turner, N., Pleiss, J. & Flitsch, S., 2 Mar 2016, In : CHEMBIOCHEM. 17, 5, p. 426-432 7 p.

    Research output: Contribution to journalArticle

  79. Published

    Enantioselective Oxidation of C-O and C-N bonds using oxidases

    Turner, N. J., 13 Jul 2011, In : Chemical Reviews. 111, 7, p. 4073-4087 14 p.

    Research output: Contribution to journalArticle

  80. Published

    Engineered Aminotransferase for the Production of d-Phenylalanine Derivatives Using Biocatalytic Cascades

    Walton, C. J. W., Parmeggiani, F., Barber, J. E. B., McCann, J. L., Turner, N. J. & Chica, R. A., 5 Dec 2017, In : ChemCatChem. 10, 2, p. 470-474 5 p.

    Research output: Contribution to journalArticle

  81. Published

    Engineering a biometallic whole cell catalyst for enantioselective deracemization reactions

    Foulkes, J. M., Malone, K. J., Coker, V. S., Turner, N. J. & Lloyd, J. R., 4 Nov 2011, In : ACS Catalysis. 1, 11, p. 1589-1594 5 p.

    Research output: Contribution to journalArticle

  82. Published

    Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products

    Ghislieri, D., Green, A., Pontini, M., Willies, S. C., Rowles, I., Frank, A., Grogan, G. & Turner, N. J., 24 Jul 2013, In : Journal of the American Chemical Society. 135, 29, p. 10863-9 7 p.

    Research output: Contribution to journalArticle

  83. Published

    Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme

    Robin, A., Roberts, G. A., Kisch, J., Sabbadin, F., Grogan, G., Bruce, N., Turner, N. J. & Flitsch, S. L., 2009, In : Chemical Communications. 18, p. 2478-2480 2 p.

    Research output: Contribution to journalArticle

  84. Published

    Engineering biocatalysts for synthesis including cascade processes

    Faber, K., Fessner, W. D. & Turner, N., 2015, In : Advanced Synthesis and Catalysis. 357, 8, p. 1565-1566

    Research output: Contribution to journalArticle

  85. Published

    Engineering of phenylalanine ammonia lyase from Rhodotorula graminis for the enhanced synthesis of unnatural L-amino acids

    Rowles, I., Groenendaal, B., Binay, B., Malone, K. J., Willies, S. C. & Turner, N. J., 17 Nov 2016, In : Tetrahedron. 72, 46, p. 7343-7347 5 p.

    Research output: Contribution to journalArticle

  86. Published

    Enzymatic Desymmetrising Redox Reactions for the Asymmetric Synthesis of Biaryl Atropisomers

    Staniland, S., Yuan, B., Giménez-Agulló, N., Marcelli, T., Willies, S. C., Grainger, D. M., Turner, N. J. & Clayden, J., 2014, In : Chemistry: A European Journal. 20, 41, p. 13084-13088

    Research output: Contribution to journalArticle

  87. Published

    Enzyme cascade reactions: Synthesis of furandicarboxylic acid (FDCA) and carboxylic acids using oxidases in tandem

    McKenna, S., Leimkühler, S., Herter, S., Turner, N. & Carnell, A. J., 2015, In : Green Chemistry. 17, 6, p. 3271-3275

    Research output: Contribution to journalArticle

  88. Published

    Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases

    Scheller, P. N., Fademrecht, S., Hofelzer, S., Pleiss, J., Leipold, F., Turner, N., Nestl, B. & Hauer, B., 2014, In : CHEMBIOCHEM. 15, 15, p. 2201-2204

    Research output: Contribution to journalArticle

  89. Published

    Enzyme-catalyzed enantioselective hydrolysis of dihydrouracils as a route to enantiomerically pure Β-amino acids

    Oneill, M., Hauer, B., Schneider, N. & Turner, N. J., 2 Sep 2011, In : ACS Catalysis. 1, 9, p. 1014-1016 2 p.

    Research output: Contribution to journalArticle

  90. Published

    Foreword

    Turner, N., Whittall, J. & Ward, T. R., 2014, In : Topics in Catalysis. 57, 5, p. 283

    Research output: Contribution to journalArticle

  91. Published

    From Multistep Enzyme Monitoring to Whole-Cell Biotransformations: Development of Real-Time Ultraviolet Resonance Raman Spectroscopy

    Fisk, H., Xu, Y., Westley, C., Turner, N., Micklefield, J. & Goodacre, R., 21 Nov 2017, In : Analytical Chemistry. 89, 22, p. 12527-12532 5 p.

    Research output: Contribution to journalArticle

  92. Published

    Galactose Oxidase Variants for the Oxidation of Amino Alcohols in Enzyme Cascade Synthesis

    Turner, N., Herter, S., McKenna, S. M., Frazer, A., Leimkühler, S. & Carnell, A. J., 2015, In : ChemCatChem. 7, 15, p. 2313-2317

    Research output: Contribution to journalArticle

  93. Published

    GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries

    Currin, A., Kwok, J., Sadler, J. C., Bell, E. L., Swainston, N., Ababi, M., Day, P., Turner, N. J. & Kell, D. B., 21 Jun 2019, In : ACS Synthetic Biology. 8, 6, p. 1371-1378

    Research output: Contribution to journalArticle

  94. Published

    Glycoprotein labeling using engineered variants of galactose oxidase obtained by directed evolution

    Rannes, J. B., Ioannou, A., Willies, S. C., Grogan, G., Behrens, C., Flitsch, S. L. & Turner, N. J., 8 Jun 2011, In : Journal of the American Chemical Society. 133, 22, p. 8436-8439 3 p.

    Research output: Contribution to journalArticle

  95. Published

    Heavily fluorinated carbohydrates as enzyme substrates: Oxidation of tetrafluorinated galactose by galactose oxidase

    Ioannou, A., Cini, E., Timofte, R. S., Flitsch, S. L., Turner, N. J. & Linclau, B., 28 Oct 2011, In : Chemical Communications. 47, 40, p. 11228-11230 2 p.

    Research output: Contribution to journalArticle

  96. Published

    High throughput screens yield small molecule inhibitors of leishmania CRK3:CYC6 cyclin-dependent kinase

    Walker, R. G., Thomson, G., Malone, K., Nowicki, M. W., Brown, E., Blake, D. G., Turner, N. J., Walkinshaw, M. D., Grant, K. M. & Mottram, J. C., Apr 2011, In : PL o S Neglected Tropical Diseases. 5, 4, e1033.

    Research output: Contribution to journalArticle

  97. Published

    Highly Productive Oxidative Biocatalysis in Continuous Flow by Enhancing the Aqueous Equilibrium Solubility of Oxygen

    Chapman, M. R., Cosgrove, S. C., Turner, N. J., Kapur, N. & Blacker, A. J., 13 Aug 2018, In : Angewandte Chemie - International Edition. 57, 33, p. 10535-10539 5 p.

    Research output: Contribution to journalArticle

  98. Published

    Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination

    France, S., Weise, N., Mangas-Sanchez, J., Montgomery, S., Howard, R. M. & Turner, N., 21 Sep 2017, In : ChemCatChem.

    Research output: Contribution to journalArticle

  99. Accepted/In press

    Imine Reductases, Reductive Aminases, and Amine Oxidases for the Synthesis of Chiral Amines: Discovery, Characterization, and Synthetic Applications

    Cosgrove, S. C., Brzezniak, A., France, S. P., Ramsden, J. I., Mangas-Sanchez, J., Montgomery, S. L., Heath, R. S. & Turner, N. J., 1 Jan 2018, (Accepted/In press) In : Methods in Enzymology.

    Research output: Contribution to journalArticle

  100. Published

    Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels

    Markošová, K., Dolejš, I., Stloukal, R., Rios-Solis, L., Rosenberg, M., Micheletti, M., Lye, G. J., Turner, N. & Rebroš, M., 1 Jul 2016, In : Journal of Molecular Catalysis - B Enzymatic. 129, p. 69-74 6 p.

    Research output: Contribution to journalArticle

  101. Published

    Immobilised whole-cell recombinant monoamine oxidase biocatalysis

    Zajkoska, P., Rosenberg, M., Heath, R., Malone, K., Stloukal, R., Turner, N. & Rebros, M., 2014, In : Applied microbiology and biotechnology. 99, 3, p. 1229-1236

    Research output: Contribution to journalArticle

Previous 1 2 Next