Prof Nicholas Turner

Professor of Chemical Biology

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  1. 2016
  2. Published

    A stereospecific solid-phase screening assay for colonies expressing both (R)- and (S)-selective ω-aminotransferases

    Willies, S., Galman, J., Slabu, I. & Turner, N., 11 Jan 2016, In : Royal Society of London. Proceedings A. Mathematical, Physical and Engineering Sciences.

    Research output: Contribution to journalArticle

  3. Published

    Whole-cell biocatalysts for stereoselective C-H amination reactions

    Both, P., Kelly, P., Mutti, F., Turner, N. & Flitsch, S., 18 Jan 2016, In : Angewandte Chemie (International Edition).

    Research output: Contribution to journalArticle

  4. Published

    InspIRED by Nature: NADPH-Dependent Imine Reductases (IREDs) as Catalysts for the Preparation of Chiral Amines

    Grogan, G. & Turner, N., 5 Feb 2016, In : Chemistry - A European Journal. 22, 6, p. 1900-1907 8 p.

    Research output: Contribution to journalArticle

  5. Published

    Case Studies Illustrating a Science and Risk-Based Approach to Ensuring Drug Quality When Using Enzymes in the Manufacture of Active Pharmaceuticals Ingredients for Oral Dosage Form

    Turner, N., Wells, A., Wong, J. W., Michels, P. C., Fandrick, K., Finch, G. L., Goswami, A., Lee, H., Mix, S., Moody, T., Pang, L., Entwistle, D. A., Sato, R. K. & Watson, T. J., 9 Feb 2016, In : Organic Process Research & Development. 20, 3, p. 3298-3306

    Research output: Contribution to journalArticle

  6. Published

    Enantioselective Benzylic Hydroxylation Catalysed by P450 Monooxygenases: Characterisation of a P450cam Mutant Library and Molecular Modelling

    Eichler, A., Gricman, Ł., Herter, S., Kelly, P., Turner, N., Pleiss, J. & Flitsch, S., 2 Mar 2016, In : CHEMBIOCHEM. 17, 5, p. 426-432 7 p.

    Research output: Contribution to journalArticle

  7. Published

    Label-Free Surface Enhanced Raman Scattering Approach for High-Throughput Screening of Biocatalysts

    Westley, C., Xu, Y., Carnell, A. J., Turner, N. & Goodacre, R., 30 Apr 2016, In : Analytical Chemistry. 88, 11, p. 5898-5903 6 p.

    Research output: Contribution to journalArticle

  8. Published

    Stereoselective Monoamine Oxidase-Catalyzed Oxidative Aza-Friedel–Crafts Reactions of meso-Pyrrolidines in Aqueous Buffer

    Turner, N., de Graaff, C., Oppelaar, B., Péruch, O., Vande Velde, C. M. L., Bechi, B., Ruijter, E. & Orru, R. V. A., May 2016, In : Advanced Synthesis and Catalysis. 358, 10, p. 1555-1560

    Research output: Contribution to journalArticle

  9. Published

    One Pot Cascade Synthesis of Mono- and Di-Substituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA) and Imine Reductase (IRED) Biocatalysts

    France, S., Hussain, S., Hill, A., Hepworth, L., Howard, R. M., Mulholland, K. R., Flitsch, S. & Turner, N., 2 May 2016, In : ACS Catalysis. p. 3753-3759

    Research output: Contribution to journalArticle

  10. Published

    Intensified biocatalytic production of enantiomerically pure halophenylalanines from acrylic acids using ammonium carbamate as the ammonia source

    Weise, N., Ahmed, S., Parmeggiani, F., Siirola, E., Pushpanath, A., Schell, U. & Turner, N., 24 May 2016, In : Catalysis Science and Technology. 6, 12, p. 4086-4089

    Research output: Contribution to journalArticle

  11. Published

    Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis

    Aleku, G. A., Man, H., France, S. P., Leipold, F., Hussain, S., Toca-Gonzalez, L., Marchington, R., Hart, S., Turkenburg, J. P., Grogan, G. & Turner, N. J., 3 Jun 2016, In : ACS Catalysis. 6, 6, p. 3880-3889 10 p.

    Research output: Contribution to journalArticle

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