Dr Mick BrownPhD.

Research Fellow

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Research interests

Mechanism of Prostate Cancer Metastasis to the Bone Marrow Stroma

  • Binding and endothelial transmigartion by malignant prostate epithelial cells
  • Invasion Stimulus
    • Lipids (Polyunsaturated Fatty Acids)
    • Inhibitors of invasion

Molecular diagnostic and prognostic indicators

  • Chemometric analysis (in collaboration with the School of Chemical Engineering and Analytical Sciences, Uni Manchester)
  • Multimarker qRT-PCR analysis of circulating cells in blood and bone marrow

Isolation and Characterisation of Urological Adult Stem Cells from Normal and Malignant Human Tissue

  • Prostate
  • Kidney
  • Bladder
  • Testes

Methodological knowledge

Hoechst 33342 dye efflux assay

Human Bone Marrow Co-cultures

    -Invasion Assays

    -Colony formation

 

Projects

Research and projects

No current projects are available for public display