I recently took up a new position as Professor of Rheumatology and Director of Experimental Medicine at the Centre for Musculoskeletal Research, University of Manchester, having moved from the University of Leeds where I retain a visiting Professor position. My translational and experimental research programme comprises two over-arching research themes (i) PRECISion medicinE across the disease continuum to prevent and treat Rheumatoid Arthritis (PRECISE-RA); with focus on optimal early strategies and refractory disease and (ii) CARDIOvascular pathology in Immune-Mediated Inflammatory Diseases (CARDIO-IMID). Deep clinical phenotyping and a ‘reverse translational’ (‘bedside to ‘bench’) approach underpins the research programme. These themes also inform my additional clinical and research interests in the rare disease, scleroderma.
I direct a broad research programme with diverse funding portolio spanning clinical trials and complex observational investigation to experimental studies; to identify prognostic and treatment predictive biomarkers and thus inform optimal management strategies.
I have been involved in several European (EULAR) task force initiatives; was Chair of the Scientific Organising Committee, EULAR 2015 and Abstract Chair for EULAR 2014. I am Deputy Chair (Chair-elect) of the NIHR UK MSK Translational Research Collaboration; NIHR-BHF cardiovascular (CV) partnership steering committee member (lead of inflammation-IMID and CV disease workstream). I sit on several Versus Arthritis (formerly Arthritis Research UK) grant committees, am section editor of Arthritis Research & Therapy and sit on the editorial board of several journals.
Visiting Professor of Rheumatology, University of Leeds1 Oct 2019
Deputy Chair (Chair-elect), NIHR UK Musculoskeletal TRC2019
Steering committee member/Lead, Inflammation-IMID work stream, NIHR-BHF Cardiovascular partnership2019