I took up a new position as Professor of Rheumatology and Director of Experimental Medicine at the Centre for Musculoskeletal Research, University of Manchester in 2019, having moved from the University of Leeds where I retain a visiting Professor position. My clinical and experimental research programme comprises the following overarching research themes (i) PRECISion medicinE across the disease continuum to prevent and treat Rheumatoid Arthritis (PRECISE-RA); with a focus on personalised therapeutics in early RA and Difficult-to-Treat-Refractory disease and (ii) CARDIOvascular pathology in Immune-Mediated Inflammatory Diseases (CARDIO-IMID) to identify patients at risk of CVD, optimal detection methods and shared mechanisms of CV-IMID comorbidity (iii) Improving therapeutics and cardiovascular outcomes in Systemic Sclerosis. In addition to clinical trials, I undertake complex observational studies and linked experimental investigation to identify prognostic, mechanistic and predictive biomarkers.
I am Chair of the NIHR-Versus Arthritis UK Musculoskeletal Translational Research Collaboration; NIHR-BHF cardiovascular (CV) partnership steering committee member and lead of the national 'CARDIO-IMID UK Network'. I have been involved in several European (EULAR) task force initiatives; was Chair of the Scientific Organising Committee, EULAR 2015 and Abstract Chair for EULAR 2014. I sit on several Versus Arthritis grant committees and on the editorial board of several journals.