Prof Marcel Van HerkPhD, MSc, BSc

Chair in Radiotherapy Physics

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Publications

  1. Article › Research › Peer-reviewed
  2. Published

    Margins for translational and rotational uncertainties: a probability-based approach.

    Van Herk, M., Remeijer, P., Rasch, C., Lebesque, J. V. & van Herk, M., 1 Jun 2002, In : International journal of radiation oncology, biology, physics. 53, 2

    Research output: Contribution to journalArticle

  3. Published

    Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients.

    Van Herk, M., Wolthaus, J. W. H., Schneider, C., Sonke, J-J., van Herk, M., Belderbos, J. S. A., Rossi, M. M. G., Lebesque, J. V. & Damen, E. M. F., 1 Aug 2006, In : International journal of radiation oncology, biology, physics. 65, 5

    Research output: Contribution to journalArticle

  4. Published

    Motion compensated digital tomosynthesis.

    Van Herk, M., van der Reijden, A., van Herk, M. & Sonke, J-J., Dec 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 109, 3

    Research output: Contribution to journalArticle

  5. Published

    MRI-guided prostate adaptive radiotherapy - A systematic review

    Mcpartlin, A., Li, X. A., Kershaw, L., van der Heide, U. A., Kerkmeijer, L., Lawton, C., Mahmood, U., Pos, F. J., Van As, N., Van Herk, M., Vesprini, D., van der Voort van Zyp, J., Tree, A., Choudhury, A. & MR-Linac consortium, Jun 2016, In : Radiotherapy and Oncology. 119, 3, p. 371-380 10 p.

    Research output: Contribution to journalArticle

  6. Published

    Multiple comparisons permutation test for image based data mining in radiotherapy.

    Van Herk, M., Chen, C., Witte, M., Heemsbergen, W. & van Herk, M., 2013, In : Radiation Oncology . 8

    Research output: Contribution to journalArticle

  7. Published

    New method to obtain the midplane dose using portal in vivo dosimetry.

    Van Herk, M., Boellaard, R., Essers, M., van Herk, M. & Mijnheer, B. J., 1 May 1998, In : International journal of radiation oncology, biology, physics. 41, 2

    Research output: Contribution to journalArticle

  8. Published

    Nodal stage migration and prognosis in anal cancer: a systematic review, meta-regression, and simulation study

    Sekhar, H., Zwahlen, M., Trelle, S., Malcomson, L., Kochhar, R., Saunders, M. P., Sperrin, M., van Herk, M., Sebag-Montefiore, D., Egger, M. & Renehan, A. G., Oct 2017, In : The Lancet. Oncology. 18, 10, p. 1348-1359 11 p.

    Research output: Contribution to journalArticle

  9. Published

    Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: a 'Big Brother' evaluation.

    Van Herk, M., Steenbakkers, R. J. H. M., Duppen, J. C., Fitton, I., Deurloo, K. E. I., Zijp, L., Uitterhoeve, A. L. J., Rodrigus, P. T. R., Kramer, G. W. P., Bussink, J., De Jaeger, K., Belderbos, J. S. A., Hart, A. A. M., Nowak, P. J. C. M., van Herk, M. & Rasch, C. R. N., Nov 2005, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 77, 2

    Research output: Contribution to journalArticle

  10. Published

    Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder.

    Van Herk, M., Ruhé, H. G., Koster, M., Booij, J., van Herk, M., Veltman, D. J. & Schene, A. H., 28 Feb 2014, In : Psychiatry Research. 221, 2

    Research output: Contribution to journalArticle

  11. Published

    One-to-one registration of en-face optical coherence tomography attenuation coefficients with histology of a prostatectomy specimen

    Swaan, A., Muller, B. G., Wilk, L. S., Almasian, M., van Kollenburg, R. A. A., Zwartkruis, E., Rozendaal, L. R., de Bruin, D. M., Faber, D. J., van Leeuwen, T. G. & van Herk, M. B., 28 Dec 2018, In : Journal of biophotonics. e201800274.

    Research output: Contribution to journalArticle

  12. Published

    Online 3D EPID-based dose verification : Proof of concept

    Spreeuw, H., Rozendaal, R., Olaciregui-Ruiz, I., Gonazalez, P., Mans, A., Mijnheer, B. & Van Herk, M., 15 Jul 2016, In : Medical Physics. 43, 7, 3969.

    Research output: Contribution to journalArticle

  13. Published

    On-the-fly motion-compensated cone-beam CT using an a priori model of the respiratory motion.

    Van Herk, M., Rit, S., Wolthaus, J. W. H., van Herk, M. & Sonke, J-J., Jun 2009, In : Medical Physics. 36, 6

    Research output: Contribution to journalArticle

  14. Published

    On-the-fly motion-compensated cone-beam CT using an a priori motion model.

    Van Herk, M., Rit, S., Wolthaus, J., van Herk, M. & Sonke, J-J., 2008, In : Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 11, Pt 1

    Research output: Contribution to journalArticle

  15. Published

    Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: a validation study

    Jelvehgaran, P., de Bruin, D. M., Khmelinskii, A., Borst, G., Steinberg, J. D., Song, J-Y., de Vos, J., van Leeuwen, T. G., Alderliesten, T., de Boer, J. F. & van Herk, M., 2019, In : Journal of biophotonics. p. e201800440

    Research output: Contribution to journalArticle

  16. Published

    Optimal combination of anti-scatter grids and software correction for CBCT imaging

    Stankovic, U., Ploeger, L. S., van Herk, M. & Sonke, J-J., Sep 2017, In : Medical Physics. 44, 9

    Research output: Contribution to journalArticle

  17. Published

    Optimization of automatic portal image analysis.

    Van Herk, M., Gilhuijs, K. G., Touw, A., van Herk, M. & Vijlbrief, R. E., Jul 1995, In : Medical Physics. 22, 7

    Research output: Contribution to journalArticle

  18. Published

    Overview of 3-year experience with large-scale electronic portal imaging device-based 3-dimensional transit dosimetry

    Mijnheer, B. J., González, P., Olaciregui-Ruiz, I., Rozendaal, R. A., van Herk, M. & Mans, A., 1 Oct 2015, In : Practical Radiation Oncology. 5, 6, p. e679-87

    Research output: Contribution to journalArticle

  19. Published

    PET motion compensation for radiation therapy using a CT-based mid-position motion model: methodology and clinical evaluation.

    Van Herk, M., Kruis, M. F., van de Kamer, J. B., Houweling, A. C., Sonke, J-J., Belderbos, J. S. A. & van Herk, M., 1 Oct 2013, In : International journal of radiation oncology, biology, physics. 87, 2

    Research output: Contribution to journalArticle

  20. Published

    Physical aspects of a liquid-filled ionization chamber with pulsed polarizing voltage.

    Van Herk, M. & van Herk, M., 1991, In : Medical Physics. 18, 4

    Research output: Contribution to journalArticle

  21. Published

    Physical aspects of a real-time tumor-tracking system for gated radiotherapy.

    Van Herk, M., Shirato, H., Shimizu, S., Kunieda, T., Kitamura, K., van Herk, M., Kagei, K., Nishioka, T., Hashimoto, S., Fujita, K., Aoyama, H., Tsuchiya, K., Kudo, K. & Miyasaka, K., 1 Nov 2000, In : International journal of radiation oncology, biology, physics. 48, 4

    Research output: Contribution to journalArticle

  22. Published

    Portal dosimetry in wedged beams.

    Spreeuw, H., Rozendaal, R., Camargo, P., Mans, A., Wendling, M., Olaciregui-Ruiz, I., Sonke, J-J., Van Herk, M. & Mijnheer, B., 2015, In : Journal of Applied Clinical Medical Physics. 16, 3

    Research output: Contribution to journalArticle

  23. Published

    Portal imaging to assess set-up errors, tumor motion and tumor shrinkage during conformal radiotherapy of non-small cell lung cancer.

    Van Herk, M., Erridge, S. C., Seppenwoolde, Y., Muller, S. H., van Herk, M., De Jaeger, K., Belderbos, J. S. A., Boersma, L. J. & Lebesque, J. V., Jan 2003, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 66, 1

    Research output: Contribution to journalArticle

  24. Published

    Position verification for the prostate: effect on rectal wall dose.

    Van Herk, M., Haverkort, M. A. D., van de Kamer, J. B., Pieters, B. R., van Tienhoven, G., Assendelft, E., Lensing, A. L., van Herk, M., de Reijke, T. M., Stoker, J. & Koning, C. C. E., 1 Jun 2011, In : International journal of radiation oncology, biology, physics. 80, 2

    Research output: Contribution to journalArticle

  25. Published

    Post-treatment lymphocytopaenia, integral body dose and overall survival in lung cancer patients treated with radical radiotherapy

    Joseph, N., McWilliam, A., Kennedy, J., Haslett, K., Mahil, J., Gavarraju, A., Mistry, H., Van Herk, M., Faivre-Finn, C. & Choudhury, A., 1 Jun 2019, In : Radiotherapy and Oncology. 135, p. 115-119 5 p.

    Research output: Contribution to journalArticle

  26. Published

    Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy.

    Van Herk, M., Seppenwoolde, Y., Shirato, H., Kitamura, K., Shimizu, S., van Herk, M., Lebesque, J. V. & Miyasaka, K., 15 Jul 2002, In : International journal of radiation oncology, biology, physics. 53, 4

    Research output: Contribution to journalArticle

  27. Published

    Probabilistic evaluation of target dose deterioration in dose painting by numbers for stage II/III lung cancer.

    Van Herk, M., Fontanarosa, D., Witte, M., Meijer, G., Shakirin, G., Steenhuijsen, J., Schuring, D., van Herk, M. & Lambin, P., 2015, In : Practical Radiation Oncology . 5, 4, p. 375-82 7 p.

    Research output: Contribution to journalArticle

  28. Published

    Probabilistic objective functions for margin-less IMRT planning.

    Van Herk, M., Bohoslavsky, R., Witte, M. G., Janssen, T. M. & van Herk, M., 7 Jun 2013, In : Physics in Medicine and Biology. 58, 11

    Research output: Contribution to journalArticle

  29. Published

    Prospective evaluation of relationships between radiotherapy dose to masticatory apparatus and trismus

    Hague, C., Beasley, W., Garcez, K., Lee, L. W., McPartlin, A., McWilliam, A., Ryder, D., Sykes, A. J., Thomson, D., van Herk, M., West, C. & Slevin, N. J., 2018, In : Acta Oncologica. p. 1-5 5 p.

    Research output: Contribution to journalArticle

  30. Published

    Prostate gland motion assessed with cine-magnetic resonance imaging (cine-MRI).

    Ghilezan, M. J., Jaffray, D. A., Siewerdsen, J. H., Van Herk, M., Shetty, A., Sharpe, M. B., Zafar Jafri, S., Vicini, F. A., Matter, R. C., Brabbins, D. S. & Martinez, A. A., 1 Jun 2005, In : International journal of radiation oncology, biology, physics. 62, 2

    Research output: Contribution to journalArticle

  31. Published

    Quantification and predictors of prostate position variability in 50 patients evaluated with multiple CT scans during conformal radiotherapy.

    Van Herk, M., Zelefsky, M. J., Crean, D., Mageras, G. S., Lyass, O., Happersett, L., Ling, C. C., Leibel, S. A., Fuks, Z., Bull, S., Kooy, H. M., van Herk, M. & Kutcher, G. J., Feb 1999, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 50, 2

    Research output: Contribution to journalArticle

  32. Published

    Quantification of local rectal wall displacements by virtual rectum unfolding.

    Van Herk, M., Hoogeman, M. S., van Herk, M., de Bois, J., Muller-Timmermans, P., Koper, P. C. M. & Lebesque, J. V., Jan 2004, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 70, 1

    Research output: Contribution to journalArticle

  33. Published

    Quantification of organ motion during conformal radiotherapy of the prostate by three dimensional image registration.

    Van Herk, M., van Herk, M., Bruce, A., Kroes, A. P., Shouman, T., Touw, A. & Lebesque, J. V., 1 Dec 1995, In : International journal of radiation oncology, biology, physics. 33, 5

    Research output: Contribution to journalArticle

  34. Published

    Quantification of shape variation of prostate and seminal vesicles during external beam radiotherapy.

    Van Herk, M., Deurloo, K. E. I., Steenbakkers, R. J. H. M., Zijp, L. J., de Bois, J. A., Nowak, P. J. C. M., Rasch, C. R. N. & van Herk, M., 1 Jan 2005, In : International journal of radiation oncology, biology, physics. 61, 1

    Research output: Contribution to journalArticle

  35. Published

    Quantification of the variability of diaphragm motion and implications for treatment margin construction.

    Van Herk, M., Rit, S., van Herk, M., Zijp, L. & Sonke, J-J., 1 Mar 2012, In : International journal of radiation oncology, biology, physics. 82, 3

    Research output: Contribution to journalArticle

  36. Published

    Quantitative evaluation of 4D Cone beam CT scans with reduced scan time in lung cancer patients

    Bryce-atkinson, A., Marchant, T., Rodgers, J., Budgell, G., Mcwilliam, A., Faivre-finn, C., Whitfield, G. & Van Herk, M., Jul 2019, In : Radiotherapy and Oncology. 136, p. 64-70 6 p.

    Research output: Contribution to journalArticle

  37. Published

    Radiation dose to heart base linked with poorer survival in lung cancer patients.

    Mcwilliam, A., Kennedy, J., Hodgson, C., Vasquez Osorio, E., Faivre-Finn, C. & Van Herk, M., Nov 2017, In : European Journal of Cancer. 85, p. 106-113 8 p.

    Research output: Contribution to journalArticle

  38. Published

    Radiation field edge detection in portal images.

    Van Herk, M., Bijhold, J., Gilhuijs, K. G., van Herk, M. & Meertens, H., Dec 1991, In : Physics in Medicine and Biology. 36, 12

    Research output: Contribution to journalArticle

  39. Published

    Radiotherapy with rectangular fields is associated with fewer clinical failures than conformal fields in the high-risk prostate cancer subgroup: results from a randomized trial.

    Van Herk, M., Heemsbergen, W. D., Al-Mamgani, A., Witte, M. G., van Herk, M. & Lebesque, J. V., May 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 107, 2

    Research output: Contribution to journalArticle

  40. Published

    Reconstruction of a time-averaged midposition CT scan for radiotherapy planning of lung cancer patients using deformable registration.

    Van Herk, M., Wolthaus, J. W. H., Sonke, J. J., van Herk, M. & Damen, E. M. F., Sep 2008, In : Medical Physics. 35, 9

    Research output: Contribution to journalArticle

  41. Published

    Reduced inter-observer and intra-observer delineation variation in esophageal cancer radiotherapy by use of fiducial markers

    Machiels, M., Jin, P., van Hooft, J. E., Gurney-Champion, O. J., Jelvehgaran, P., Geijsen, E. D., Jeene, P. M., Willemijn Kolff, M., Oppedijk, V., Rasch, C. R. N., van Herk, M. B., Alderliesten, T. & Hulshof, M. C. C. M., 2019, In : Acta Oncologica . p. 1-8 8 p.

    Research output: Contribution to journalArticle

  42. Published

    Reduction of dose delivered to the rectum and bulb of the penis using MRI delineation for radiotherapy of the prostate.

    Van Herk, M., Steenbakkers, R. J. H. M., Deurloo, K. E. I., Nowak, P. J. C. M., Lebesque, J. V., van Herk, M. & Rasch, C. R. N., 1 Dec 2003, In : International journal of radiation oncology, biology, physics. 57, 5

    Research output: Contribution to journalArticle

  43. Published

    Reduction of observer variation using matched CT-PET for lung cancer delineation: a three-dimensional analysis.

    Van Herk, M., Steenbakkers, R. J. H. M., Duppen, J. C., Fitton, I., Deurloo, K. E. I., Zijp, L. J., Comans, E. F. I., Uitterhoeve, A. L. J., Rodrigus, P. T. R., Kramer, G. W. P., Bussink, J., De Jaeger, K., Belderbos, J. S. A., Nowak, P. J. C. M., van Herk, M. & Rasch, C. R. N., 1 Feb 2006, In : International journal of radiation oncology, biology, physics. 64, 2

    Research output: Contribution to journalArticle

  44. Published

    Regional analysis of volumes and reproducibilities of automatic and manual hippocampal segmentations

    Bartel, F., Vrenken, H., Bijma, F., Barkhof, F., Van Herk, M. & De Munck, J. C., 9 Feb 2017, In : PLoS ONE. 12, 2, e0166785.

    Research output: Contribution to journalArticle

  45. Published

    Registration accuracy and image quality of time averaged mid-position CT scans for liver SBRT.

    Van Herk, M., Kruis, M. F., van de Kamer, J. B., Sonke, J-J., Jansen, E. P. M. & van Herk, M., Dec 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 109, 3

    Research output: Contribution to journalArticle

  46. Published

    Registration of MR and SPECT without using external fiducial markers.

    Van Herk, M., de Munck, J. C., Verster, F. C., Dubois, E. A., Habraken, J. B., Boltjes, B., Claus, J. J. & van Herk, M., May 1998, In : Physics in Medicine and Biology. 43, 5

    Research output: Contribution to journalArticle

  47. Published

    Relating dose outside the prostate with freedom from failure in the Dutch trial 68 Gy vs. 78 Gy.

    Van Herk, M., Witte, M. G., Heemsbergen, W. D., Bohoslavsky, R., Pos, F. J., Al-Mamgani, A., Lebesque, J. V. & van Herk, M., 1 May 2010, In : International journal of radiation oncology, biology, physics. 77, 1

    Research output: Contribution to journalArticle

  48. Published

    Repeat CT assessed CTV variation and PTV margins for short- and long-course pre-operative RT of rectal cancer.

    Van Herk, M., Nijkamp, J., Swellengrebel, M., Hollmann, B., de Jong, R., Marijnen, C., van Vliet-Vroegindeweij, C., van Triest, B., van Herk, M. & Sonke, J-J., Mar 2012, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 102, 3

    Research output: Contribution to journalArticle

  49. Published

    Replacing pretreatment verification with in vivo EPID dosimetry for prostate IMRT.

    Van Herk, M., McDermott, L. N., Wendling, M., Sonke, J-J., van Herk, M. & Mijnheer, B. J., 1 Apr 2007, In : International journal of radiation oncology, biology, physics. 67, 5

    Research output: Contribution to journalArticle

  50. Published

    Reproducibility of the bladder shape and bladder shape changes during filling.

    Van Herk, M., Lotz, H. T., van Herk, M., Betgen, A., Pos, F., Lebesque, J. V. & Remeijer, P., Aug 2005, In : Medical Physics. 32, 8

    Research output: Contribution to journalArticle

  51. Published

    Residual seminal vesicle displacement in marker-based image-guided radiotherapy for prostate cancer and the impact on margin design.

    Van Herk, M., Smitsmans, M. H. P., de Bois, J., Sonke, J-J., Catton, C. N., Jaffray, D. A., Lebesque, J. V. & van Herk, M., 1 Jun 2011, In : International journal of radiation oncology, biology, physics. 80, 2

    Research output: Contribution to journalArticle

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