Prof Marcel Van HerkPhD, MSc, BSc

Chair in Radiotherapy Physics

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Publications

  1. Article › Research › Peer-reviewed
  2. Published

    Feasibility of geometrical verification of patient set-up using body contours and computed tomography data.

    Van Herk, M., Ploeger, L. S., Betgen, A., Gilhuijs, K. G. A. & van Herk, M., Feb 2003, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 66, 2

    Research output: Contribution to journalArticle

  3. Published

    Feasibility of using optical coherence tomography to detect acute radiation-induced esophageal damage in small animal models

    Jelvehgaran, P., de Bruin, D. M., Salguero, F. J., Borst, G. R., Song, J-Y., van Leeuwen, T. G., de Boer, J. F., Alderliesten, T. & van Herk, M., Apr 2018, In : Journal of Biomedical Optics. 23, 4, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  4. Published

    Feasibility of using optical coherence tomography to detect radiation-induced fibrosis and residual cancer extent after neoadjuvant chemo-radiation therapy: an ex vivo study

    Jelvehgaran, P., Alderliesten, T., Georgiou, G., Meijer, S. L., Bloemen, P. R., Kodach, L. L., Van Laarhoven, H. W. M., Van Berge Henegouwen, M. I., Hulshof, M. C. C. M., Rasch, C. R. N., Van Leeuwen, T. G., De Boer, J. F., De Bruin, M. & Van Herk, M., 2018, In : Biomedical Optics Express. 9, 9

    Research output: Contribution to journalArticle

  5. Published

    Field size reduction enables iso-NTCP escalation of tumor control probability for irradiation of lung tumors.

    Van Herk, M., Engelsman, M., Remeijer, P., van Herk, M., Lebesque, J. V., Mijnheer, B. J. & Damen, E. M., 1 Dec 2001, In : International journal of radiation oncology, biology, physics. 51, 5

    Research output: Contribution to journalArticle

  6. Published

    Finite element based bladder modeling for image-guided radiotherapy of bladder cancer.

    Van Herk, M., Chai, X., van Herk, M., van de Kamer, J. B., Hulshof, M. C. C. M., Remeijer, P., Lotz, H. T. & Bel, A., Jan 2011, In : Medical Physics. 38, 1

    Research output: Contribution to journalArticle

  7. Published

    First clinical experience with a multiple region of interest registration and correction method in radiotherapy of head-and-neck cancer patients.

    Van Herk, M., van Beek, S., van Kranen, S., Mencarelli, A., Remeijer, P., Rasch, C., van Herk, M. & Sonke, J-J., Feb 2010, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 94, 2

    Research output: Contribution to journalArticle

  8. Published

    First clinical experience with a newly developed electronic portal imaging device.

    Van Herk, M., Meertens, H., van Herk, M., Bijhold, J. & Bartelink, H., May 1990, In : International journal of radiation oncology, biology, physics. 18, 5

    Research output: Contribution to journalArticle

  9. Published

    First clinical tests using a liquid-filled electronic portal imaging device and a convolution model for the verification of the midplane dose.

    Van Herk, M., Boellaard, R., van Herk, M., Uiterwaal, H. & Mijnheer, B., Jun 1998, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 47, 3

    Research output: Contribution to journalArticle

  10. Published

    Focal spot motion of linear accelerators and its effect on portal image analysis.

    Van Herk, M., Sonke, J-J., Brand, B. & van Herk, M., Jun 2003, In : Medical Physics. 30, 6

    Research output: Contribution to journalArticle

  11. Published

    Frameless stereotactic body radiotherapy for lung cancer using four-dimensional cone beam CT guidance.

    Van Herk, M., Sonke, J-J., Rossi, M., Wolthaus, J., van Herk, M., Damen, E. & Belderbos, J., 1 Jun 2009, In : International journal of radiation oncology, biology, physics. 74, 2

    Research output: Contribution to journalArticle

  12. Published

    Fusion of planning CT and cystoscopy images for bladder tumor delineation: a feasibility study.

    Van Herk, M., Dees-Ribbers, H. M., Pos, F. J., Betgen, A., Bex, A., Hulshof, M. C. C. M., Remeijer, P. & van Herk, M., May 2013, In : Medical Physics. 40, 5

    Research output: Contribution to journalArticle

  13. Published

    Fusion of respiration-correlated PET and CT scans: correlated lung tumour motion in anatomical and functional scans.

    Van Herk, M., Wolthaus, J. W. H., van Herk, M., Muller, S. H., Belderbos, J. S. A., Lebesque, J. V., de Bois, J. A., Rossi, M. M. G. & Damen, E. M. F., 7 Apr 2005, In : Physics in Medicine and Biology. 50, 7

    Research output: Contribution to journalArticle

  14. Published

    Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes

    van Kranen, S., Hamming-Vrieze, O., Wolf, A., Damen, E., van Herk, M. & Sonke, J. J., 1 Nov 2016, In : International Journal of Radiation Oncology Biology Physics. 96, 3, p. 653-660 8 p.

    Research output: Contribution to journalArticle

  15. Published

    Hybrid registration of prostate and seminal vesicles for image guided radiation therapy.

    Van Herk, M., de Boer, J., van Herk, M., Pos, F. J. & Sonke, J-J., 1 May 2013, In : International journal of radiation oncology, biology, physics. 86, 1

    Research output: Contribution to journalArticle

  16. Published

    Image fusion for stereotactic radiotherapy and radiosurgery treatment planning.

    Van Herk, M., Kooy, H. M., van Herk, M., Barnes, P. D., Alexander, E., Dunbar, S. F., Tarbell, N. J., Mulkern, R. V., Holupka, E. J. & Loeffler, J. S., 30 Mar 1994, In : International journal of radiation oncology, biology, physics. 28, 5

    Research output: Contribution to journalArticle

  17. Published

    Image Guided Radiation Therapy Strategies for Pelvic Lymph Node Irradiation in High-Risk Prostate Cancer: Motion and Margins

    Kershaw, L., van Zadelhoff, L., Heemsbergen, W., Pos, F. & van Herk, M., 1 Jan 2018, In : International Journal of Radiation Oncology Biology Physics.

    Research output: Contribution to journalArticle

  18. Published

    Image-based Data Mining to Probe Dosimetric Correlates of Radiation-induced Trismus

    Beasley, W., Thor, M., Mcwilliam, A., Mackay, R., Slevin, N., Olsson, C., Pettersson, N., Finizia, C., Estilo, C., Riaz, N., Lee, N. Y., Deasy, J. O., Van Herk, M. & Green, A., 15 Nov 2018, In : International Journal of Radiation: Oncology - Biology - Physics. 102, 4, p. 1330-1338 9 p.

    Research output: Contribution to journalArticle

  19. Published

    Imaging biomarker roadmap for cancer studies

    O'Connor, J. P. B., Aboagye, E. O., Adams, J. E., Aerts, H. J. W. L., Barrington, S. F., Beer, A. J., Boellaard, R., Bohndiek, S. E., Brady, M., Brown, G., Buckley, D. L., Chenevert, T. L., Clarke, L. P., Collette, S., Cook, G. J., deSouza, N. M., Dickson, J. C., Dive, C., Evelhoch, J. L., Faivre-Finn, C. & 57 others, Gallagher, F. A., Gilbert, F. J., Gillies, R. J., Goh, V., Griffiths, J. R., Groves, A. M., Halligan, S., Harris, A. L., Hawkes, D. J., Hoekstra, O. S., Huang, E. P., Hutton, B. F., Jackson, E. F., Jayson, G. C., Jones, A., Koh, D. M., Lacombe, D., Lambin, P., Lassau, N., Leach, M. O., Lee, T. Y., Leen, E. L., Lewis, J. S., Liu, Y., Lythgoe, M. F., Manoharan, P., Maxwell, R. J., Miles, K. A., Morgan, B., Morris, S., Ng, T., Padhani, A. R., Parker, G. J. M., Partridge, M., Pathak, A. P., Peet, A. C., Punwani, S., Reynolds, A. R., Robinson, S. P., Shankar, L. K., Sharma, R. A., Soloviev, D., Stroobants, S., Sullivan, D. C., Taylor, S. A., Tofts, P. S., Tozer, G. M., van Herk, M., Walker-Samuel, S., Wason, J., Williams, K., Workman, P., Yankeelov, T. E., Brindle, K. M., McShane, L. M., Jackson, A. & Waterton, J. C., 2017, In : Nature Reviews Clinical Oncology. 14, 3, p. 169-186

    Research output: Contribution to journalArticle

  20. Published

    Impact of anatomical location on value of CT-PET co-registration for delineation of lung tumors.

    Van Herk, M., Fitton, I., Steenbakkers, R. J. H. M., Gilhuijs, K., Duppen, J. C., Nowak, P. J. C. M., van Herk, M. & Rasch, C. R. N., 1 Apr 2008, In : International journal of radiation oncology, biology, physics. 70, 5

    Research output: Contribution to journalArticle

  21. Published

    Impact of coronal and sagittal views on lung gross tumor volume delineation

    Fitton, I., Duppen, J. C., Steenbakkers, R. J. H. M., Lotz, H., Nowak, P. J. C. M., Rasch, C. R. N. & van Herk, M., 2016, In : Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 32, 9, p. 1082-7 6 p.

    Research output: Contribution to journalArticle

  22. Published

    Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer.

    Van Herk, M., Rozendaal, R. A., Mijnheer, B. J., Hamming-Vrieze, O., Mans, A. & van Herk, M., 30 Jun 2015, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

    Research output: Contribution to journalArticle

  23. Published

    Impact of geometrical uncertainties on 3D CRT and IMRT dose distributions for lung cancer treatment.

    Schwarz, M., Van der Geer, J., Van Herk, M., Lebesque, J. V., Mijnheer, B. J. & Damen, E. M. F., 15 Jul 2006, In : International journal of radiation oncology, biology, physics. 65, 4

    Research output: Contribution to journalArticle

  24. Published

    Impact of knee support and shape of tabletop on rectum and prostate position.

    Van Herk, M., Steenbakkers, R. J. H. M., Duppen, J. C., Betgen, A., Lotz, H. T., Remeijer, P., Fitton, I., Nowak, P. J. C. M., van Herk, M. & Rasch, C. R. N., 1 Dec 2004, In : International journal of radiation oncology, biology, physics. 60, 5

    Research output: Contribution to journalArticle

  25. Published

    Improved image quality of cone beam CT scans for radiotherapy image guidance using fiber-interspaced antiscatter grid.

    Van Herk, M., Stankovic, U., van Herk, M., Ploeger, L. S. & Sonke, J-J., Jun 2014, In : Medical Physics. 41, 6

    Research output: Contribution to journalArticle

  26. Published

    IMRT optimization including random and systematic geometric errors based on the expectation of TCP and NTCP.

    Van Herk, M., Witte, M. G., van der Geer, J., Schneider, C., Lebesque, J. V., Alber, M. & van Herk, M., Sep 2007, In : Medical Physics. 34, 9

    Research output: Contribution to journalArticle

  27. Published

    In aqua vivo EPID dosimetry.

    Van Herk, M., Wendling, M., McDermott, L. N., Mans, A., Olaciregui-Ruiz, Í., Pecharromán-Gallego, R., Sonke, J-J., Stroom, J., van Herk, M. & Mijnheer, B. J., Jan 2012, In : Medical Physics. 39, 1

    Research output: Contribution to journalArticle

  28. Published

    In vivo portal dosimetry for head-and-neck VMAT and lung IMRT: linking γ-analysis with differences in dose-volume histograms of the PTV.

    Van Herk, M., Rozendaal, R. A., Mijnheer, B. J., van Herk, M. & Mans, A., Sep 2014, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 112, 3

    Research output: Contribution to journalArticle

  29. Published

    Inclusion of geometric uncertainties in treatment plan evaluation.

    Van Herk, M., van Herk, M., Remeijer, P. & Lebesque, J. V., 1 Apr 2002, In : International journal of radiation oncology, biology, physics. 52, 5

    Research output: Contribution to journalArticle

  30. Published

    Influence of the number of elongated fiducial markers on the localization accuracy of the prostate.

    Van Herk, M., de Boer, J., de Bois, J., van Herk, M. & Sonke, J-J., 7 Oct 2012, In : Physics in Medicine and Biology. 57, 19

    Research output: Contribution to journalArticle

  31. Published
  32. Published

    In-situ imaging of articular cartilage of the first carpometacarpal joint using co-registered optical coherence tomography and computed tomography

    Cernohorsky, P., de Bruin, D. M., van Herk, M., Bras, J., Faber, D. J., Strackee, S. D. & van Leeuwen, T. G., Jun 2012, In : Journal of Biomedical Optics. 17, 6, p. 060501

    Research output: Contribution to journalArticle

  33. Published

    Inter- and intra-fractional bladder motion during radiotherapy for bladder cancer: a comparison of full and empty bladders.

    Van Herk, M., Dees-Ribbers, H. M., Betgen, A., Pos, F. J., Witteveen, T., Remeijer, P. & van Herk, M., Nov 2014, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 113, 2

    Research output: Contribution to journalArticle

  34. Published

    Interactive three dimensional inspection of patient setup in radiation therapy using digital portal images and computed tomography data.

    Van Herk, M., Gilhuijs, K. G., Drukker, K., Touw, A., van de Ven, P. J. & van Herk, M., 1 Mar 1996, In : International journal of radiation oncology, biology, physics. 34, 4

    Research output: Contribution to journalArticle

  35. Published

    Interobserver variability in the delineation of the primary lung cancer and lymph nodes on different four-dimensional computed tomography reconstructions

    Mercieca, S., Belderbos, J. S. A., De Jaeger, K., Schinagl, D. A. X., van der Voort Van Zijp, N., Pomp, J., Theuws, J., Khalifa, J., van de Vaart, P. & van Herk, M., Feb 2018, In : Radiotherapy and Oncology. 126, 2

    Research output: Contribution to journalArticle

  36. Published

    Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation

    Bartel, F., Van Herk, M., Vrenken, H., Vandaele, F., Sunaert, S., De Jaeger, K., Dollekamp, N. J., Carbaat, C., Lamers, E., Dieleman, E. M. T., Lievens, Y., De Ruysscher, D., Schagen, S. B., De Ruiter, M. B., De Munck, J. C. & Belderbos, J., 2018, In : Clinical and Translational Oncology.

    Research output: Contribution to journalArticle

  37. Published

    Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET)

    Mackay, R., Van Herk, M., Faivre-Finn, C. & ART-NET Steering Committee, 2017, In : Clinical Oncology.

    Research output: Contribution to journalArticle

  38. Published

    Irradiation of paranasal sinus tumors, a delineation and dose comparison study.

    Van Herk, M., Rasch, C., Eisbruch, A., Remeijer, P., Bos, L., Hoogeman, M., van Herk, M. & Lebesque, J. V., 1 Jan 2002, In : International journal of radiation oncology, biology, physics. 52, 1

    Research output: Contribution to journalArticle

  39. Published
  40. Published

    Kilo-voltage cone-beam computed tomography setup measurements for lung cancer patients; first clinical results and comparison with electronic portal-imaging device.

    Van Herk, M., Borst, G. R., Sonke, J-J., Betgen, A., Remeijer, P., van Herk, M. & Lebesque, J. V., 1 Jun 2007, In : International journal of radiation oncology, biology, physics. 68, 2

    Research output: Contribution to journalArticle

  41. Published

    Leaf position verification during dynamic beam delivery: a comparison of three applications using electronic portal imaging.

    Van Herk, M., Partridge, M., Evans, P. M., van Herk, M., Ploeger, L. S., Budgell, G. J. & James, H. V., Jul 2000, In : Medical Physics. 27, 7

    Research output: Contribution to journalArticle

  42. Published

    Leaf trajectory verification during dynamic intensity modulated radiotherapy using an amorphous silicon flat panel imager.

    Van Herk, M., Sonke, J-J., Ploeger, L. S., Brand, B., Smitsmans, M. H. P. & van Herk, M., Feb 2004, In : Medical Physics. 31, 2

    Research output: Contribution to journalArticle

  43. Published

    Learning from every patient treated

    Van Herk, M., Mcwilliam, A., Green, A., osorio, E. V., Beasley, W., Choudhury, A. & Faivre-Finn, C., 2018, In : Physica Medica. 52, p. 165 1 p.

    Research output: Contribution to journalArticle

  44. Published

    Leukemia and brain tumors among children after radiation exposure from CT scans: design and methodological opportunities of the Dutch Pediatric CT Study.

    Van Herk, M., Meulepas, J. M., Ronckers, C. M., Smets, A. M. J. B., Nievelstein, R. A. J., Jahnen, A., Lee, C., Kieft, M., Laméris, J. S., van Herk, M., Greuter, M. J. W., Jeukens, C. R. L. P. N., van Straten, M., Visser, O., van Leeuwen, F. E. & Hauptmann, M., Apr 2014, In : European journal of epidemiology. 29, 4

    Research output: Contribution to journalArticle

  45. Published

    Lipiodol injection for target volume delineation and image guidance during radiotherapy for bladder cancer.

    Van Herk, M., Pos, F., Bex, A., Dees-Ribbers, H. M., Betgen, A., van Herk, M. & Remeijer, P., Nov 2009, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 93, 2

    Research output: Contribution to journalArticle

  46. Accepted/In press

    Magnetic resonance guided radiation therapy: a review

    Chin, S., Eccles, C., Mcwilliam, A., Chuter, R., Walker, E., Whitehurst, P., Berresford, J., Van Herk, M., Hoskin, P. & Choudhury, A., 24 Sep 2019, (Accepted/In press) In : Journal of Medical Imaging and Radiation Oncology .

    Research output: Contribution to journalArticle

  47. Published

    Magnetic resonance image-directed stereotactic neurosurgery: use of image fusion with computerized tomography to enhance spatial accuracy.

    Van Herk, M., Alexander, E., Kooy, H. M., van Herk, M., Schwartz, M., Barnes, P. D., Tarbell, N., Mulkern, R. V., Holupka, E. J. & Loeffler, J. S., Aug 1995, In : Journal of neurosurgery. 83, 2

    Research output: Contribution to journalArticle

  48. Published

    Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A “Game Changer” for Prostate Treatment?

    Pathmanathan, A. U., van As, N. J., Kerkmeijer, L. G. W., Christodouleas, J., Lawton, C. A. F., Vesprini, D., van der Heide, U. A., Frank, S. J., Nill, S., Oelfke, U., Van Herk, M., Allen Li, X., Mittauer, K., Ritter, M., Choudhury, A. & Tree, A. C., 1 Feb 2018, In : International Journal of Radiation: Oncology - Biology - Physics. 100, 2, p. 361-373 12 p.

    Research output: Contribution to journalArticle

  49. Accepted/In press

    Making radiotherapy smarter

    Van Herk, M. & Vasquez Osorio, E., 30 Jul 2019, (Accepted/In press) In : Lancet Oncology.

    Research output: Contribution to journalArticle

  50. Published

    Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion

    Kartachova, M. S., Valdés Olmos, R. A., Haas, R. L. M., Hoebers, F. J. P., van den Brekel, M. W., van Zandwijk, N., Herk, M. V. & Verheij, M., Aug 2006, In : European Journal of Nuclear Medicine and Molecular Imaging. 33, 8, p. 893-9 7 p.

    Research output: Contribution to journalArticle

  51. Published

    Margins for geometric uncertainty around organs at risk in radiotherapy.

    Van Herk, M., McKenzie, A., van Herk, M. & Mijnheer, B., Mar 2002, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 62, 3

    Research output: Contribution to journalArticle

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