Prof Marcel Van HerkPhD, MSc, BSc

Chair in Radiotherapy Physics

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Publications

  1. 2017
  2. Published

    ADDED VALUE IN DISCRIMINATION PERFORMANCE OF TUMOUR PARAMETERS AND NOVEL FEATURES DETERMINED USING ROUTINE PRE-TREATMENT MRI IN PATIENTS WITH ANAL CANCER.

    Sekhar, H., Kochhar, R., Carrington, B., Sperrin, M., Saunders, M., Van Herk, M., Sebag-Montefiore, D. & Renehan, A., Jun 2017, In : Diseases of the Colon and Rectum. 60, 6, p. E106-E106

    Research output: Contribution to journalMeeting Abstract

  3. Published

    A population based statistical model for daily geometric variations in the thorax

    Szeto, Y. Z., Witte, M. G., van Herk, M. & Sonke, J-J., Apr 2017, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 123, 1, p. 99-105 7 p.

    Research output: Contribution to journalArticle

  4. Published

    Considerable interobserver variation in delineation of pancreatic cancer on 3DCT and 4DCT: A multi-institutional study

    Versteijne, E., Gurney-Champion, O. J., van der Horst, A., Lens, E., Kolff, M. W., Buijsen, J., Ebrahimi, G., Neelis, K. J., Rasch, C. R. N., Stoker, J., van Herk, M., Bel, A. & van Tienhoven, G., 23 Mar 2017, In : Practical Radiation Oncology . 12, 1, p. 58 58.

    Research output: Contribution to journalArticle

  5. Published

    Regional analysis of volumes and reproducibilities of automatic and manual hippocampal segmentations

    Bartel, F., Vrenken, H., Bijma, F., Barkhof, F., Van Herk, M. & De Munck, J. C., 9 Feb 2017, In : PLoS ONE. 12, 2, e0166785.

    Research output: Contribution to journalArticle

  6. Published

    High resolution toxicity analysis of lung cancer patients identifies the base of the heart as a dose sensitive region

    McWilliam, A., Kennedy, J., Faivre-Finn, C. & Van Herk, M., Jan 2017, p. S2(4).

    Research output: Contribution to conferenceAbstract

  7. Published

    Organ at risk inter- and intra-observer contour variation for lung patients on average versus motion compensated 4DCT

    McWilliam, A., Lee, L., Harris, M., Sheikh, H., Pemberton, L., Faivre-Finn, C. & Van Herk, M., Jan 2017, p. S52(117).

    Research output: Contribution to conferenceAbstract

  8. Published

    Addition of MRI for CT-based pancreatic tumor delineation: a feasibility study

    Gurney-Champion, O. J., Versteijne, E., van der Horst, A., Lens, E., Rütten, H., Heerkens, H. D., Paardekooper, G. M. R. M., Berbee, M., Rasch, C. R. N., Stoker, J., Engelbrecht, M. R. W., van Herk, M., Nederveen, A. J., Klaassen, R., van Laarhoven, H. W. M., van Tienhoven, G. & Bel, A., 2017, In : Acta Oncologica. 56, 7, p. 1-8 8 p.

    Research output: Contribution to journalArticle

  9. Published
  10. Published

    Imaging biomarker roadmap for cancer studies

    O'Connor, J. P. B., Aboagye, E. O., Adams, J. E., Aerts, H. J. W. L., Barrington, S. F., Beer, A. J., Boellaard, R., Bohndiek, S. E., Brady, M., Brown, G., Buckley, D. L., Chenevert, T. L., Clarke, L. P., Collette, S., Cook, G. J., deSouza, N. M., Dickson, J. C., Dive, C., Evelhoch, J. L., Faivre-Finn, C. & 57 others, Gallagher, F. A., Gilbert, F. J., Gillies, R. J., Goh, V., Griffiths, J. R., Groves, A. M., Halligan, S., Harris, A. L., Hawkes, D. J., Hoekstra, O. S., Huang, E. P., Hutton, B. F., Jackson, E. F., Jayson, G. C., Jones, A., Koh, D. M., Lacombe, D., Lambin, P., Lassau, N., Leach, M. O., Lee, T. Y., Leen, E. L., Lewis, J. S., Liu, Y., Lythgoe, M. F., Manoharan, P., Maxwell, R. J., Miles, K. A., Morgan, B., Morris, S., Ng, T., Padhani, A. R., Parker, G. J. M., Partridge, M., Pathak, A. P., Peet, A. C., Punwani, S., Reynolds, A. R., Robinson, S. P., Shankar, L. K., Sharma, R. A., Soloviev, D., Stroobants, S., Sullivan, D. C., Taylor, S. A., Tofts, P. S., Tozer, G. M., van Herk, M., Walker-Samuel, S., Wason, J., Williams, K., Workman, P., Yankeelov, T. E., Brindle, K. M., McShane, L. M., Jackson, A. & Waterton, J. C., 2017, In : Nature Reviews Clinical Oncology. 14, 3, p. 169-186

    Research output: Contribution to journalArticle

  11. Published

    Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET)

    Mackay, R., Van Herk, M., Faivre-Finn, C. & ART-NET Steering Committee, 2017, In : Clinical Oncology.

    Research output: Contribution to journalArticle

  12. Published

    MRI Guided Radiotherapy: A Short SWOT Analysis

    van Herk, M., McWilliam, A., Dubec, M., Faivre-Finn, C. & Choudhury, A., 2017, Imaging & Oncology . London: Society and College of Radiographers, p. 20-27

    Research output: Chapter in Book/Report/Conference proceedingChapter

  13. Published

    The feasibility of manual parameter tuning for deformable breast MR image registration from a multi-objective optimization perspective

    Pirpinia, K., Bosman, P. A. N., Loo, C. E., Winter-Warnars, G., Janssen, N. N. Y., Scholten, A. N., Sonke, J-J., Van Herk, M. & Alderliesten, T., 2017, In : Physics in Medicine and Biology. 62, 14, p. 5723-5743 21 p.

    Research output: Contribution to journalArticle

  14. Published

    The influence of automation on tumor contouring

    Aselmaa, A., van Herk, M., Song, Y., Goossens, R. H. M. & Laprie, A., 2017, In : Cognition, Technology and Work. p. 1-14 14 p.

    Research output: Contribution to journalArticle

  15. Published

    Using a contextualized sensemaking model for interaction design: A case study of tumor contouring

    Aselmaa, A., van Herk, M., Laprie, A., Nestle, U., Götz, I., Wiedenmann, N., Schimek-Jasch, T., Picaud, F., Syrykh, C., Cagetti, L. V., Jolnerovski, M., Song, Y. & Goossens, R. H. M., 2017, In : Journal of Biomedical Informatics.

    Research output: Contribution to journalArticle

  16. 2016
  17. Published

    An automated workflow for patient-specific quality control of contour propagation

    Beasley, W., Mcwilliam, A., Slevin, N., Mackay, R. & Van Herk, M., 23 Nov 2016, In : Physics in Medicine and Biology. 61, 24, p. 8577-8586 10 p.

    Research output: Contribution to journalArticle

  18. Published

    Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes

    van Kranen, S., Hamming-Vrieze, O., Wolf, A., Damen, E., van Herk, M. & Sonke, J. J., 1 Nov 2016, In : International Journal of Radiation Oncology Biology Physics. 96, 3, p. 653-660 8 p.

    Research output: Contribution to journalArticle

  19. Published

    Online 3D EPID-based dose verification : Proof of concept

    Spreeuw, H., Rozendaal, R., Olaciregui-Ruiz, I., Gonazalez, P., Mans, A., Mijnheer, B. & Van Herk, M., 15 Jul 2016, In : Medical Physics. 43, 7, 3969.

    Research output: Contribution to journalArticle

  20. Published

    MRI-guided prostate adaptive radiotherapy - A systematic review

    Mcpartlin, A., Li, X. A., Kershaw, L., van der Heide, U. A., Kerkmeijer, L., Lawton, C., Mahmood, U., Pos, F. J., Van As, N., Van Herk, M., Vesprini, D., van der Voort van Zyp, J., Tree, A., Choudhury, A. & MR-Linac consortium, Jun 2016, In : Radiotherapy and Oncology. 119, 3, p. 371-380 10 p.

    Research output: Contribution to journalArticle

  21. Published

    Clinical introduction of image lag correction for a cone beam CT system

    Stankovic, U., Ploeger, LS., Sonke, JJ. & Van Herk, M., 5 Mar 2016, In : Medical Physics. 43, 3, p. 1057-1064

    Research output: Contribution to journalArticle

  22. Published

    Effects of anatomical changes on pencil beam scanning proton plans in locally advanced NSCLC patients

    Szeto, Y. Z., Witte, M. G., van Kranen, S. R., Sonke, J-J., Belderbos, J. & van Herk, M., 2016, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

    Research output: Contribution to journalArticle

  23. Published

    Impact of coronal and sagittal views on lung gross tumor volume delineation

    Fitton, I., Duppen, J. C., Steenbakkers, R. J. H. M., Lotz, H., Nowak, P. J. C. M., Rasch, C. R. N. & van Herk, M., 2016, In : Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 32, 9, p. 1082-7 6 p.

    Research output: Contribution to journalArticle

  24. 2015
  25. Published

    Clinical evaluation of respiration-induced attenuation uncertainties in pulmonary 3D PET/CT.

    Kruis, MF., van, D. K. JB., Vogel, WV., Belderbos, JS., Sonke, JJ. & Van Herk, M., Dec 2015, In : European Journal of Nuclear Medicine and Molecular Imaging. 2, 4

    Research output: Contribution to journalArticle

  26. Published

    Dose-surface maps identifying local dose-effects for acute gastrointestinal toxicity after radiotherapy for prostate cancer

    Wortel, R. C., Witte, M. G., van der Heide, U. A., Pos, F. J., Lebesque, J. V., van Herk, M., Incrocci, L. & Heemsbergen, W. D., Dec 2015, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 117, 3, p. 515-20 6 p.

    Research output: Contribution to journalArticle

  27. Published

    Overview of 3-year experience with large-scale electronic portal imaging device-based 3-dimensional transit dosimetry

    Mijnheer, B. J., González, P., Olaciregui-Ruiz, I., Rozendaal, R. A., van Herk, M. & Mans, A., 1 Oct 2015, In : Practical Radiation Oncology. 5, 6, p. e679-87

    Research output: Contribution to journalArticle

  28. Published

    CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.

    Brouwer, C., Steenbakkers, R. J. H. M., Bourhis, J., Budach, W., Grau, C., Gregoire, V., Van Herk, M., Lee, A., Maingon, P., Nutting, C., O'Sullivan, B., Porceddu, S. V., Rosenthal, D., Sijtsemaa, N. & Langendijka, J., Oct 2015, In : Radiotherapy & Oncology. 117, 1, p. 83-90 7 p., j.ejca.2015.09.013.

    Research output: Contribution to journalArticle

  29. Published

    Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer.

    Van Herk, M., Rozendaal, R. A., Mijnheer, B. J., Hamming-Vrieze, O., Mans, A. & van Herk, M., 30 Jun 2015, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

    Research output: Contribution to journalArticle

  30. Published

    Dynamic CT perfusion image data compression for efficient parallel processing.

    Van Herk, M., Barros, R. S., Olabarriaga, S. D., Borst, J., van Walderveen, M. A. A., Posthuma, J. S., Streekstra, G. J., van Herk, M., Majoie, C. B. L. M. & Marquering, H. A., 24 Jun 2015, In : Medical & biological engineering & computing.

    Research output: Contribution to journalArticle

  31. Published

    Establishing implantation uncertainties for focal brachytherapy with I-125 seeds for the treatment of localized prostate cancer.

    Van Herk, M., Polders, D. L., Steggerda, M., van Herk, M., Nichol, K., Witteveen, T., Moonen, L., Nijkamp, J. & van der Heide, U. A., Jun 2015, In : Acta Oncologica . 54, 6

    Research output: Contribution to journalArticle

  32. Published

    WE-D-BRA-04: Online 3D EPID-Based Dose Verification for Optimum Patient Safety.

    Van Herk, M., Spreeuw, H., Rozendaal, R., Olaciregui-Ruiz, I., Mans, A., Mijnheer, B., van Herk, M. & Gonzalez, P., Jun 2015, In : Medical Physics. 42, 6

    Research output: Contribution to journalArticle

  33. Published

    Dynamic collimator angle adjustments during volumetric modulated arc therapy to account for prostate rotations.

    Van Herk, M., de Boer, J., Wolf, A. L., Szeto, Y. Z., van Herk, M. & Sonke, J-J., 1 Apr 2015, In : International journal of radiation oncology, biology, physics. 91, 5

    Research output: Contribution to journalArticle

  34. Published

    Comment on 'Multi-modality functional image guided dose escalation in the presence of uncertainties'

    Witte, M. G., Lebesque, J. V. & van Herk, M., Apr 2015, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 115, 1, p. 149

    Research output: Contribution to journalArticle

  35. Published

    Acute toxicity after image-guided intensity modulated radiation therapy compared to 3D conformal radiation therapy in prostate cancer patients.

    Van Herk, M., Wortel, R. C., Incrocci, L., Pos, F. J., Lebesque, J. V., Witte, M. G., van der Heide, U. A., van Herk, M. & Heemsbergen, W. D., 15 Mar 2015, In : International journal of radiation oncology, biology, physics. 91, 4

    Research output: Contribution to journalArticle

  36. Published

    Target delineation variability and corresponding margins of peripheral early stage NSCLC treated with stereotactic body radiotherapy.

    Van Herk, M., Peulen, H., Belderbos, J., Guckenberger, M., Hope, A., Grills, I., van Herk, M. & Sonke, J-J., Mar 2015, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 114, 3

    Research output: Contribution to journalArticle

  37. Published

    Toward adaptive radiotherapy for head and neck patients: Uncertainties in dose warping due to the choice of deformable registration algorithm.

    Van Herk, M., Veiga, C., Lourenço, A. M., Mouinuddin, S., van Herk, M., Modat, M., Ourselin, S., Royle, G. & McClelland, J. R., Feb 2015, In : Medical Physics. 42, 2

    Research output: Contribution to journalArticle

  38. Published

    Portal dosimetry in wedged beams.

    Spreeuw, H., Rozendaal, R., Camargo, P., Mans, A., Wendling, M., Olaciregui-Ruiz, I., Sonke, J-J., Van Herk, M. & Mijnheer, B., 2015, In : Journal of Applied Clinical Medical Physics. 16, 3

    Research output: Contribution to journalArticle

  39. Published

    Probabilistic evaluation of target dose deterioration in dose painting by numbers for stage II/III lung cancer.

    Van Herk, M., Fontanarosa, D., Witte, M., Meijer, G., Shakirin, G., Steenhuijsen, J., Schuring, D., van Herk, M. & Lambin, P., 2015, In : Practical Radiation Oncology . 5, 4, p. 375-82 7 p.

    Research output: Contribution to journalArticle

  40. 2014
  41. Published

    Deformable image registration for adaptive radiation therapy of head and neck cancer: accuracy and precision in the presence of tumor changes.

    Van Herk, M., Mencarelli, A., van Kranen, S. R., Hamming-Vrieze, O., van Beek, S., Nico Rasch, C. R., van Herk, M. & Sonke, J-J., 1 Nov 2014, In : International journal of radiation oncology, biology, physics. 90, 3

    Research output: Contribution to journalArticle

  42. Published

    Inter- and intra-fractional bladder motion during radiotherapy for bladder cancer: a comparison of full and empty bladders.

    Van Herk, M., Dees-Ribbers, H. M., Betgen, A., Pos, F. J., Witteveen, T., Remeijer, P. & van Herk, M., Nov 2014, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 113, 2

    Research output: Contribution to journalArticle

  43. Published

    Clinical implementation and rapid commissioning of an EPID based in-vivo dosimetry system.

    Van Herk, M., Hanson, I. M., Hansen, V. N., Olaciregui-Ruiz, I. & van Herk, M., 7 Oct 2014, In : Physics in Medicine and Biology. 59, 19

    Research output: Contribution to journalArticle

  44. Published

    4D CT amplitude binning for the generation of a time-averaged 3D mid-position CT scan.

    Van Herk, M., Kruis, M. F., van de Kamer, J. B., Belderbos, J. S. A., Sonke, J-J. & van Herk, M., 21 Sep 2014, In : Physics in Medicine and Biology. 59, 18

    Research output: Contribution to journalArticle

  45. Published

    In vivo portal dosimetry for head-and-neck VMAT and lung IMRT: linking γ-analysis with differences in dose-volume histograms of the PTV.

    Van Herk, M., Rozendaal, R. A., Mijnheer, B. J., van Herk, M. & Mans, A., Sep 2014, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 112, 3

    Research output: Contribution to journalArticle

  46. Published

    Improved image quality of cone beam CT scans for radiotherapy image guidance using fiber-interspaced antiscatter grid.

    Van Herk, M., Stankovic, U., van Herk, M., Ploeger, L. S. & Sonke, J-J., Jun 2014, In : Medical Physics. 41, 6

    Research output: Contribution to journalArticle

  47. Published

    Automatic detection system for multiple region of interest registration to account for posture changes in head and neck radiotherapy.

    Van Herk, M., Mencarelli, A., van Beek, S., Zijp, L. J., Rasch, C., van Herk, M. & Sonke, J-J., 21 Apr 2014, In : Physics in Medicine and Biology. 59, 8

    Research output: Contribution to journalArticle

  48. Published

    Leukemia and brain tumors among children after radiation exposure from CT scans: design and methodological opportunities of the Dutch Pediatric CT Study.

    Van Herk, M., Meulepas, J. M., Ronckers, C. M., Smets, A. M. J. B., Nievelstein, R. A. J., Jahnen, A., Lee, C., Kieft, M., Laméris, J. S., van Herk, M., Greuter, M. J. W., Jeukens, C. R. L. P. N., van Straten, M., Visser, O., van Leeuwen, F. E. & Hauptmann, M., Apr 2014, In : European journal of epidemiology. 29, 4

    Research output: Contribution to journalArticle

  49. Published

    Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder.

    Van Herk, M., Ruhé, H. G., Koster, M., Booij, J., van Herk, M., Veltman, D. J. & Schene, A. H., 28 Feb 2014, In : Psychiatry Research. 221, 2

    Research output: Contribution to journalArticle

  50. 2013
  51. Published

    Adaptive radiotherapy with an average anatomy model: evaluation and quantification of residual deformations in head and neck cancer patients.

    Van Herk, M., van Kranen, S., Mencarelli, A., van Beek, S., Rasch, C., van Herk, M. & Sonke, J-J., Dec 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 109, 3

    Research output: Contribution to journalArticle

  52. Published

    An in silico comparison between margin-based and probabilistic target-planning approaches in head and neck cancer patients.

    Van Herk, M., Fontanarosa, D., van der Laan, H. P., Witte, M., Shakirin, G., Roelofs, E., Langendijk, J. A., Lambin, P. & van Herk, M., Dec 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 109, 3

    Research output: Contribution to journalArticle

  53. Published

    Motion compensated digital tomosynthesis.

    Van Herk, M., van der Reijden, A., van Herk, M. & Sonke, J-J., Dec 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 109, 3

    Research output: Contribution to journalArticle

  54. Published

    Registration accuracy and image quality of time averaged mid-position CT scans for liver SBRT.

    Van Herk, M., Kruis, M. F., van de Kamer, J. B., Sonke, J-J., Jansen, E. P. M. & van Herk, M., Dec 2013, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 109, 3

    Research output: Contribution to journalArticle

  55. Published

    Automatic in vivo portal dosimetry of all treatments.

    Van Herk, M., Olaciregui-Ruiz, I., Rozendaal, R., Mijnheer, B., van Herk, M. & Mans, A., 21 Nov 2013, In : Physics in Medicine and Biology. 58, 22

    Research output: Contribution to journalArticle

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