Prof Marcel Van HerkPhD, MSc, BSc

Chair in Radiotherapy Physics

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Publications

  1. Published

    New approaches for effective and safe pelvic radiotherapy in high-risk prostate cancer

    Tharmalingam, H., Choudhury, A., Van Herk, M., McWilliam, A. & Hoskin, P. J., 2019, In : Nature Reviews Urology.

    Research output: Contribution to journalReview article

  2. Published

    Effects of anatomical changes on pencil beam scanning proton plans in locally advanced NSCLC patients

    Szeto, Y. Z., Witte, M. G., van Kranen, S. R., Sonke, J-J., Belderbos, J. & van Herk, M., 2016, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

    Research output: Contribution to journalArticle

  3. Published

    A population based statistical model for daily geometric variations in the thorax

    Szeto, Y. Z., Witte, M. G., van Herk, M. & Sonke, J-J., Apr 2017, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 123, 1, p. 99-105 7 p.

    Research output: Contribution to journalArticle

  4. Published

    One-to-one registration of en-face optical coherence tomography attenuation coefficients with histology of a prostatectomy specimen

    Swaan, A., Muller, B. G., Wilk, L. S., Almasian, M., van Kollenburg, R. A. A., Zwartkruis, E., Rozendaal, L. R., de Bruin, D. M., Faber, D. J., van Leeuwen, T. G. & van Herk, M. B., 28 Dec 2018, In : Journal of biophotonics. e201800274.

    Research output: Contribution to journalArticle

  5. Published

    Clinical introduction of image lag correction for a cone beam CT system

    Stankovic, U., Ploeger, LS., Sonke, JJ. & Van Herk, M., 5 Mar 2016, In : Medical Physics. 43, 3, p. 1057-1064

    Research output: Contribution to journalArticle

  6. Published

    Optimal combination of anti-scatter grids and software correction for CBCT imaging

    Stankovic, U., Ploeger, L. S., van Herk, M. & Sonke, J-J., Sep 2017, In : Medical Physics. 44, 9

    Research output: Contribution to journalArticle

  7. Published

    Portal dosimetry in wedged beams.

    Spreeuw, H., Rozendaal, R., Camargo, P., Mans, A., Wendling, M., Olaciregui-Ruiz, I., Sonke, J-J., Van Herk, M. & Mijnheer, B., 2015, In : Journal of Applied Clinical Medical Physics. 16, 3

    Research output: Contribution to journalArticle

  8. Published

    Online 3D EPID-based dose verification : Proof of concept

    Spreeuw, H., Rozendaal, R., Olaciregui-Ruiz, I., Gonazalez, P., Mans, A., Mijnheer, B. & Van Herk, M., 15 Jul 2016, In : Medical Physics. 43, 7, 3969.

    Research output: Contribution to journalArticle

  9. Published
  10. Published

    Nodal stage migration and prognosis in anal cancer: a systematic review, meta-regression, and simulation study

    Sekhar, H., Zwahlen, M., Trelle, S., Malcomson, L., Kochhar, R., Saunders, M. P., Sperrin, M., van Herk, M., Sebag-Montefiore, D., Egger, M. & Renehan, A. G., Oct 2017, In : The Lancet. Oncology. 18, 10, p. 1348-1359 11 p.

    Research output: Contribution to journalArticle

  11. Published

    ADDED VALUE IN DISCRIMINATION PERFORMANCE OF TUMOUR PARAMETERS AND NOVEL FEATURES DETERMINED USING ROUTINE PRE-TREATMENT MRI IN PATIENTS WITH ANAL CANCER.

    Sekhar, H., Kochhar, R., Carrington, B., Sperrin, M., Saunders, M., Van Herk, M., Sebag-Montefiore, D. & Renehan, A., Jun 2017, In : Diseases of the Colon and Rectum. 60, 6, p. E106-E106

    Research output: Contribution to journalMeeting Abstract

  12. Published

    Impact of geometrical uncertainties on 3D CRT and IMRT dose distributions for lung cancer treatment.

    Schwarz, M., Van der Geer, J., Van Herk, M., Lebesque, J. V., Mijnheer, B. J. & Damen, E. M. F., 15 Jul 2006, In : International journal of radiation oncology, biology, physics. 65, 4

    Research output: Contribution to journalArticle

  13. Published

    Strategy for online correction of rotational organ motion for intensity-modulated radiotherapy of prostate cancer

    Rijkhorst, E-J., van Herk, M., Lebesque, J. V. & Sonke, J-J., 1 Dec 2007, In : International journal of radiation oncology, biology, physics. 69, 5, p. 1608-17 10 p.

    Research output: Contribution to journalArticle

  14. Published
  15. Published

    The feasibility of manual parameter tuning for deformable breast MR image registration from a multi-objective optimization perspective

    Pirpinia, K., Bosman, P. A. N., Loo, C. E., Winter-Warnars, G., Janssen, N. N. Y., Scholten, A. N., Sonke, J-J., Van Herk, M. & Alderliesten, T., 2017, In : Physics in Medicine and Biology. 62, 14, p. 5723-5743 21 p.

    Research output: Contribution to journalArticle

  16. Published

    Simplex-based navigation tool for a posteriori selection of the preferred deformable image registration outcome from a set of trade-off solutions obtained with multiobjective optimization for the case of breast MRI

    Pirpinia, K., Bosman, P. A. N., Loo, C. E., Russell, N. S., Van Herk, M. B. & Alderliesten, T., 2018, In : Journal of Medical Imaging. 5, 4, 045501.

    Research output: Contribution to journalArticle

  17. Published

    Evolutionary machine learning for multi-objective class solutions in medical deformable image registration

    Pirpinia, K., Bosman, P. A. N., Sonke, J. J., van Herk, M. & Alderliesten, T., 9 May 2019, In : Algorithms. 12, 5, 99.

    Research output: Contribution to journalArticle

  18. Published

    Evolutionary multi-objective meta-optimization of deformation and tissue removal parameters improves the performance of deformable image registration of pre- and post-surgery images

    Pirpinia, K., Bosman, P. A. N., Sonke, J. J., Van Herk, M. & Alderliesten, T., 2019, Medical Imaging 2019: Image Processing. Landman, B. A., Angelini, E. D., Angelini, E. D. & Angelini, E. D. (eds.). SPIE, 1094939. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10949).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  19. Published

    Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A “Game Changer” for Prostate Treatment?

    Pathmanathan, A. U., van As, N. J., Kerkmeijer, L. G. W., Christodouleas, J., Lawton, C. A. F., Vesprini, D., van der Heide, U. A., Frank, S. J., Nill, S., Oelfke, U., Van Herk, M., Allen Li, X., Mittauer, K., Ritter, M., Choudhury, A. & Tree, A. C., 1 Feb 2018, In : International Journal of Radiation: Oncology - Biology - Physics. 100, 2, p. 361-373 12 p.

    Research output: Contribution to journalArticle

  20. Published

    Imaging biomarker roadmap for cancer studies

    O'Connor, J. P. B., Aboagye, E. O., Adams, J. E., Aerts, H. J. W. L., Barrington, S. F., Beer, A. J., Boellaard, R., Bohndiek, S. E., Brady, M., Brown, G., Buckley, D. L., Chenevert, T. L., Clarke, L. P., Collette, S., Cook, G. J., deSouza, N. M., Dickson, J. C., Dive, C., Evelhoch, J. L., Faivre-Finn, C. & 57 others, Gallagher, F. A., Gilbert, F. J., Gillies, R. J., Goh, V., Griffiths, J. R., Groves, A. M., Halligan, S., Harris, A. L., Hawkes, D. J., Hoekstra, O. S., Huang, E. P., Hutton, B. F., Jackson, E. F., Jayson, G. C., Jones, A., Koh, D. M., Lacombe, D., Lambin, P., Lassau, N., Leach, M. O., Lee, T. Y., Leen, E. L., Lewis, J. S., Liu, Y., Lythgoe, M. F., Manoharan, P., Maxwell, R. J., Miles, K. A., Morgan, B., Morris, S., Ng, T., Padhani, A. R., Parker, G. J. M., Partridge, M., Pathak, A. P., Peet, A. C., Punwani, S., Reynolds, A. R., Robinson, S. P., Shankar, L. K., Sharma, R. A., Soloviev, D., Stroobants, S., Sullivan, D. C., Taylor, S. A., Tofts, P. S., Tozer, G. M., van Herk, M., Walker-Samuel, S., Wason, J., Williams, K., Workman, P., Yankeelov, T. E., Brindle, K. M., McShane, L. M., Jackson, A. & Waterton, J. C., 2017, In : Nature Reviews Clinical Oncology. 14, 3, p. 169-186

    Research output: Contribution to journalArticle

  21. Published

    Short-term displacement and reproducibility of the breast and nodal targets under active breathing control.

    Moran, J. M., Balter, J. M., Ben-David, M. A., Marsh, R. B., Van Herk, M. & Pierce, L. J., 1 Jun 2007, In : International journal of radiation oncology, biology, physics. 68, 2

    Research output: Contribution to journalArticle

  22. Published

    Overview of 3-year experience with large-scale electronic portal imaging device-based 3-dimensional transit dosimetry

    Mijnheer, B. J., González, P., Olaciregui-Ruiz, I., Rozendaal, R. A., van Herk, M. & Mans, A., 1 Oct 2015, In : Practical Radiation Oncology. 5, 6, p. e679-87

    Research output: Contribution to journalArticle

  23. Published

    Interobserver variability in the delineation of the primary lung cancer and lymph nodes on different four-dimensional computed tomography reconstructions

    Mercieca, S., Belderbos, J. S. A., De Jaeger, K., Schinagl, D. A. X., van der Voort Van Zijp, N., Pomp, J., Theuws, J., Khalifa, J., van de Vaart, P. & van Herk, M., Feb 2018, In : Radiotherapy and Oncology. 126, 2

    Research output: Contribution to journalArticle

  24. Published

    Comparison of SUVmax and SUVpeak based segmentation to determine primary lung tumour volume on FDG PET-CT correlated with pathology data

    Mercieca, S., Belderbos, J., Van Loon, J., Gilhuijs, K., Julyan, P. & Van Herk, M., 1 Aug 2018, In : Radiotherapy and Oncology.

    Research output: Contribution to journalArticle

  25. Published

    The impact of training and professional collaboration on the interobserver variation of lung cancer delineations: a multi-institutional study

    Mercieca, S., Belderbos, J. S. A., van Baardwijk, A., Delorme, S. & van Herk, M., 2018, In : Acta Oncologica . p. 1-9 9 p.

    Research output: Contribution to journalArticle

  26. Published

    High resolution toxicity analysis of lung cancer patients identifies the base of the heart as a dose sensitive region

    McWilliam, A., Kennedy, J., Faivre-Finn, C. & Van Herk, M., Jan 2017, p. S2(4).

    Research output: Contribution to conferenceAbstract

  27. Published

    Organ at risk inter- and intra-observer contour variation for lung patients on average versus motion compensated 4DCT

    McWilliam, A., Lee, L., Harris, M., Sheikh, H., Pemberton, L., Faivre-Finn, C. & Van Herk, M., Jan 2017, p. S52(117).

    Research output: Contribution to conferenceAbstract

  28. Published

    Radiation dose to heart base linked with poorer survival in lung cancer patients.

    Mcwilliam, A., Kennedy, J., Hodgson, C., Vasquez Osorio, E., Faivre-Finn, C. & Van Herk, M., Nov 2017, In : European Journal of Cancer. 85, p. 106-113 8 p.

    Research output: Contribution to journalArticle

  29. Published

    The Challenges of Using MRI During Radiotherapy

    Mcwilliam, A., Rowland, B. & Van Herk, M., 2018, In : Clinical Oncology.

    Research output: Contribution to journalArticle

  30. Published
  31. Published

    MRI-guided prostate adaptive radiotherapy - A systematic review

    Mcpartlin, A., Li, X. A., Kershaw, L., van der Heide, U. A., Kerkmeijer, L., Lawton, C., Mahmood, U., Pos, F. J., Van As, N., Van Herk, M., Vesprini, D., van der Voort van Zyp, J., Tree, A., Choudhury, A. & MR-Linac consortium, Jun 2016, In : Radiotherapy and Oncology. 119, 3, p. 371-380 10 p.

    Research output: Contribution to journalArticle

  32. Published

    Changes in prostate apparent diffusion coefficient values during radiotherapy after neo-adjuvant hormones

    Mcpartlin, A., Kershaw, L., Mcwilliam, A., Van Herk, M., Taylor, B. & Choudhury, A., 1 Dec 2018, In : Therapeutic advances in Urology. 10, 12, p. 359-364 5 p.

    Research output: Contribution to journalArticle

  33. Published

    Reduced inter-observer and intra-observer delineation variation in esophageal cancer radiotherapy by use of fiducial markers

    Machiels, M., Jin, P., van Hooft, J. E., Gurney-Champion, O. J., Jelvehgaran, P., Geijsen, E. D., Jeene, P. M., Willemijn Kolff, M., Oppedijk, V., Rasch, C. R. N., van Herk, M. B., Alderliesten, T. & Hulshof, M. C. C. M., 2019, In : Acta Oncologica . p. 1-8 8 p.

    Research output: Contribution to journalArticle

  34. Published

    Clinical evaluation of respiration-induced attenuation uncertainties in pulmonary 3D PET/CT.

    Kruis, MF., van, D. K. JB., Vogel, WV., Belderbos, JS., Sonke, JJ. & Van Herk, M., Dec 2015, In : European Journal of Nuclear Medicine and Molecular Imaging. 2, 4

    Research output: Contribution to journalArticle

  35. Published

    Image Guided Radiation Therapy Strategies for Pelvic Lymph Node Irradiation in High-Risk Prostate Cancer: Motion and Margins

    Kershaw, L., van Zadelhoff, L., Heemsbergen, W., Pos, F. & van Herk, M., 1 Jan 2018, In : International Journal of Radiation Oncology Biology Physics.

    Research output: Contribution to journalArticle

  36. Published

    The management of respiratory motion in radiation oncology report of AAPM Task Group 76.

    Keall, P. J., Mageras, G. S., Balter, J. M., Emery, R. S., Forster, K. M., Jiang, S. B., Kapatoes, J. M., Low, D. A., Murphy, M. J., Murray, B. R., Ramsey, C. R., Van Herk, M. B., Vedam, S. S., Wong, J. W. & Yorke, E., Oct 2006, In : Medical Physics. 33, 10

    Research output: Contribution to journalArticle

  37. Published

    Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion

    Kartachova, M. S., Valdés Olmos, R. A., Haas, R. L. M., Hoebers, F. J. P., van den Brekel, M. W., van Zandwijk, N., Herk, M. V. & Verheij, M., Aug 2006, In : European Journal of Nuclear Medicine and Molecular Imaging. 33, 8, p. 893-9 7 p.

    Research output: Contribution to journalArticle

  38. Published

    Post-treatment lymphocytopaenia, integral body dose and overall survival in lung cancer patients treated with radical radiotherapy

    Joseph, N., McWilliam, A., Kennedy, J., Haslett, K., Mahil, J., Gavarraju, A., Mistry, H., Van Herk, M., Faivre-Finn, C. & Choudhury, A., 1 Jun 2019, In : Radiotherapy and Oncology. 135, p. 115-119 5 p.

    Research output: Contribution to journalArticle

  39. Published
  40. Published

    A method to combine target volume data from 3D and 4D planned thoracic radiotherapy patient cohorts for machine learning applications

    Johnson, C., Price, G., Khalifa, J., Faivre-Finn, C., Dekker, A., Moore, C. & Van Herk, M., Feb 2018, In : Radiotherapy and Oncology.

    Research output: Contribution to journalArticle

  41. Published

    Residual setup errors towards the heart after image guidance linked with poorer survival in lung cancer patients: do we need stricter IGRT protocols?

    Johnson, C. N., Price, G. J., Faivre-Finn, C., Aznar, M. C. & van Herk, M., 2018, In : International journal of radiation oncology, biology, physics.

    Research output: Contribution to journalArticle

  42. Published

    Image-guided radiotherapy residual setup errors linked to overall survival in lung cancer patients

    Johnson, C. N., Price, G. J., Faivre-Finn, C. & van Herk, M., 2018, European Society for Radiotherapy and Oncology. (European Society for Radiotherapy and Oncology).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  43. Published

    Feasibility of using optical coherence tomography to detect acute radiation-induced esophageal damage in small animal models

    Jelvehgaran, P., de Bruin, D. M., Salguero, F. J., Borst, G. R., Song, J-Y., van Leeuwen, T. G., de Boer, J. F., Alderliesten, T. & van Herk, M., Apr 2018, In : Journal of Biomedical Optics. 23, 4, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  44. Published

    Visibility of fiducial markers used for image-guided radiation therapy on optical coherence tomography for registration with CT: An esophageal phantom study

    Jelvehgaran, P., Alderliesten, T., Weda, J. J. A., de Bruin, M., Faber, D. J., Hulshof, M. C. C. M., van Leeuwen, T. G., van Herk, M. & de Boer, J. F., Dec 2017, In : Medical Physics. 44, 12, p. 6570-6582 13 p.

    Research output: Contribution to journalArticle

  45. Published

    Feasibility of using optical coherence tomography to detect radiation-induced fibrosis and residual cancer extent after neoadjuvant chemo-radiation therapy: an ex vivo study

    Jelvehgaran, P., Alderliesten, T., Georgiou, G., Meijer, S. L., Bloemen, P. R., Kodach, L. L., Van Laarhoven, H. W. M., Van Berge Henegouwen, M. I., Hulshof, M. C. C. M., Rasch, C. R. N., Van Leeuwen, T. G., De Boer, J. F., De Bruin, M. & Van Herk, M., 2018, In : Biomedical Optics Express. 9, 9

    Research output: Contribution to journalArticle

  46. Published

    Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: a validation study

    Jelvehgaran, P., de Bruin, D. M., Khmelinskii, A., Borst, G., Steinberg, J. D., Song, J-Y., de Vos, J., van Leeuwen, T. G., Alderliesten, T., de Boer, J. F. & van Herk, M., 2019, In : Journal of biophotonics. p. e201800440

    Research output: Contribution to journalArticle

  47. Published

    Clinical use of electronic portal imaging: report of AAPM Radiation Therapy Committee Task Group 58.

    Herman, M. G., Balter, J. M., Jaffray, D. A., McGee, K. P., Munro, P., Shalev, S., Van Herk, M. & Wong, J. W., May 2001, In : Medical Physics. 28, 5

    Research output: Contribution to journalArticle

  48. Published

    Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET)

    Mackay, R., Van Herk, M., Faivre-Finn, C. & ART-NET Steering Committee, 2017, In : Clinical Oncology.

    Research output: Contribution to journalArticle

  49. Published

    Prospective evaluation of relationships between radiotherapy dose to masticatory apparatus and trismus

    Hague, C., Beasley, W., Garcez, K., Lee, L. W., McPartlin, A., McWilliam, A., Ryder, D., Sykes, A. J., Thomson, D., van Herk, M., West, C. & Slevin, N. J., 2018, In : Acta Oncologica. p. 1-5 5 p.

    Research output: Contribution to journalArticle

  50. Published

    Use of a novel atlas for muscles of mastication to reduce inter observer variability in head and neck radiotherapy contouring

    Hague, C., Beasley, W., Dixon, L., Gaito, S., Garcez, K., Green, A., Lee, L. W., Maranzano, M., McPartlin, A., Mistry, H., Mullan, D., Sykes, A. J., Thomson, D., Van Herk, M., West, C. M. & Slevin, N., 2018, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

    Research output: Contribution to journalArticle

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