Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. 2011
  2. Published

    Critique of the two-fold measure of prediction success for ratios: Application for the assessment of drug-drug interactions

    Guest, E. J., Aarons, L., Houston, J. B., Rostami-Hodjegan, A. & Galetin, A., Feb 2011, In : Drug Metabolism and Disposition. 39, 2, p. 170-173 3 p.

    Research output: Contribution to journalArticle

  3. Published

    Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: Results of a dose-ranging study

    Galea, J., Ogungbenro, K., Hulme, S., Greenhalgh, A., Aarons, L., Scarth, S., Hutchinson, P., Grainger, S., King, A., Hopkins, S. J., Rothwell, N. & Tyrrell, P., Feb 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 439-447 8 p.

    Research output: Contribution to journalArticle

  4. Published

    Corticosteroid-binding globulin regulates cortisol pharmacokinetics

    Perogamvros, I., Aarons, L., Miller, A. G., Trainer, P. J. & Ray, D. W., Jan 2011, In : Clinical Endocrinology. 74, 1, p. 30-36 6 p.

    Research output: Contribution to journalArticle

  5. Published

    Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1

    Danson, S. J., Johnson, P., Ward, T. H., Dawson, M., Denneny, O., Dickinson, G., Aarons, L., Watson, A., Jowle, D., Cummings, J., Robson, L., Halbert, G., Dive, C. & Ranson, M., 2011, In : Annals of Oncology. 22, 7, p. 1653-1660 7 p.

    Research output: Contribution to journalArticle

  6. 2010
  7. Published

    Development of a novel method for updating the predicted partition coefficient values generated by an existing in silico prediction method

    Graham, H., Yates, J., Galetin, A. & Aarons, L., Nov 2010, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  8. Published

    Sample-size calculations for multi-group comparison in population pharmacokinetic experiments

    Ogungbenro, K. & Aarons, L., Oct 2010, In : Pharmaceutical Statistics. 9, 4, p. 255-268 13 p.

    Research output: Contribution to journalArticle

  9. Published

    Sample size/power calculations for population pharmacodynamic experiments involving repeated-count measurements

    Ogungbenro, K. & Aarons, L., Sep 2010, In : Journal of Biopharmaceutical Statistics. 20, 5, p. 1026-1042 16 p.

    Research output: Contribution to journalArticle

  10. Published

    Optimal design of pharmacokinetic studies

    Aarons, L. & Ogungbenro, K., Mar 2010, In : Basic and Clinical Pharmacology and Toxicology. 106, 3, p. 250-255 5 p.

    Research output: Contribution to journalArticle

  11. Published
  12. Published

    Ethnic differences in the population pharmacokinetics and pharmacodynamics of warfarin

    Yuen, E., Gueorguieva, I., Wise, S., Soon, D. & Aarons, L., Feb 2010, In : Journal of pharmacokinetics and pharmacodynamics. 37, 1, p. 3-24 21 p.

    Research output: Contribution to journalArticle

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