Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. 2012
  2. Published

    Structural identifiability analysis and reparameterisation (parameter reduction) of a cardiovascular feedback model

    Cheung, S. Y. A., Majid, O., Yates, J. W. T. & Aarons, L., 16 Jul 2012, In : European Journal of Pharmaceutical Sciences. 46, 4, p. 259-271 12 p.

    Research output: Contribution to journalArticle

  3. Published

    Population pharmacokinetic modelling of S-warfarin to evaluate the design of drug-drug interaction studies for CYP2C9

    Klein, K., Gueorguieva, I. & Aarons, L., Apr 2012, In : Journal of pharmacokinetics and pharmacodynamics. 39, 2, p. 147-160 13 p.

    Research output: Contribution to journalArticle

  4. Published

    Comparison of in-vivo and in-silico methods used for prediction of tissue: Plasma partition coefficients in rat

    Graham, H., Walker, M., Jones, O., Yates, J., Galetin, A. & Aarons, L., Mar 2012, In : Journal of Pharmacy and Pharmacology. 64, 3, p. 383-396 13 p.

    Research output: Contribution to journalArticle

  5. Published

    A semi-mechanistic gastric emptying pharmacokinetic model for 13C-octanoic acid: An evaluation using simulation

    Ogungbenro, K. & Aarons, L., 14 Feb 2012, In : European Journal of Pharmaceutical Sciences. 45, 3, p. 302-310 8 p.

    Research output: Contribution to journalArticle

  6. Published

    The population pharmacokinetics of R- and S-warfarin: Effect of genetic and clinical factors

    Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Park, B. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. & Pirmohamed, M., Jan 2012, In : British Journal of Clinical Pharmacology. 73, 1, p. 66-76 10 p.

    Research output: Contribution to journalArticle

  7. 2011
  8. Published

    Population pharmacokinetic analysis of ropivacaine and its metabolite 2′,6′-pipecoloxylidide from pooled data in neonates, infants, and children

    Aarons, L., Sadler, B., Pitsiu, M., Sjövall, J., Henriksson, J. & Molnár, V., Sep 2011, In : British Journal of Anaesthesia. 107, 3, p. 409-424 15 p.

    Research output: Contribution to journalArticle

  9. Published

    Population Fisher information matrix and optimal design of discrete data responses in population pharmacodynamic experiments

    Ogungbenro, K. & Aarons, L., Aug 2011, In : Journal of pharmacokinetics and pharmacodynamics. 38, 4, p. 449-469 20 p.

    Research output: Contribution to journalArticle

  10. Published

    Sequential population pharmacokinetic modeling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies

    Dickinson, L., Boffito, M., Back, D., Else, L., Von Hentig, N., Davies, G., Khoo, S., Pozniak, A., Moyle, G. & Aarons, L., Jun 2011, In : Antimicrobial Agents and Chemotherapy. 55, 6, p. 2775-2782 7 p.

    Research output: Contribution to journalArticle

  11. Published

    Structural identifiability analysis of pharmacokinetic models using DAISY: Semi-mechanistic gastric emptying models for 13C-octanoic acid

    Ogungbenro, K. & Aarons, L., Apr 2011, In : Journal of pharmacokinetics and pharmacodynamics. 38, 2, p. 279-292 13 p.

    Research output: Contribution to journalArticle

  12. Published

    A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients

    Ogungbenro, K., Vasist, L., Maclaren, R., Dukes, G., Young, M. & Aarons, L., Feb 2011, In : Pharmaceutical Research. 28, 2, p. 394-404 10 p.

    Research output: Contribution to journalArticle

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