Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. 2015
  2. Published

    Model of mucociliary clearance in cystic fibrosis lungs.

    Kurbatova, P., Bessonov, N., Volpert, V., Tiddens, H. A. W. M., Cornu, C., Nony, P., Caudri, D., Aarons, L., Bajard, A., Bertrand, Y., Bretz, F., Castellan, C., Chabaud, S., Cornu, C., Dufour, F., Eymard, N., Fisch, R., Guerrini, R., Kassai, B., Kurbatova, P. & 13 othersMalik, S., Nony, P., Ogungbenro, K., Pérol, D., Pons, G., Tiddens, H., Rosati, A., Alberti, C., Chiron, C., Nabbout, R., Jullien, V., Benquet, P. & Wendling, F., 7 May 2015, In : Journal of Theoretical Biology. 372

    Research output: Contribution to journalArticle

  3. Published

    Model-based evaluation of the impact of formulation and food intake on the complex oral absorption of mavoglurant in healthy subjects.

    Wendling, T., Ogungbenro, K., Pigeolet, E., Dumitras, S., Woessner, R. & Aarons, L., May 2015, In : Pharmaceutical Research. 32, 5, p. 1764-1778 14 p.

    Research output: Contribution to journalArticle

  4. Published

    Analysis of the impact of controlled release formulation on oral drug absorption, gut wall metabolism and relative bioavailability of CYP3A substrates using a physiologically-based pharmacokinetic model

    Olivares-Morales, A., Kamiyama, Y., Darwich, A. S., Aarons, L. & Rostami, A., 25 Jan 2015, In : European Journal of Pharmaceutical Sciences. 67, p. 32-44 12 p.

    Research output: Contribution to journalArticle

  5. Published

    Empirical and semi-mechanistic modelling of double-peaked pharmacokinetic profile phenomenon due to gastric emptying.

    Ogungbenro, K., Pertinez, H. & Aarons, L., Jan 2015, In : The AAPS journal. 17, 1

    Research output: Contribution to journalArticle

  6. Published

    Combining the "bottom-up" and "top-down" approaches in pharmacokinetic modelling: Fitting PBPK models to observed clinical data

    Tsamandouras, N., Rostami-Hochaghan, A. & Aarons, L., 2015, In : British Journal of Clinical Pharmacology. 79, 1, p. 48-55 7 p.

    Research output: Contribution to journalArticle

  7. Published

    Development and Application of a Mechanistic Pharmacokinetic Model for Simvastatin and its Active Metabolite Simvastatin Acid Using an Integrated Population PBPK Approach

    Tsamandouras, N., Dickinson, G., Guo, Y., Hall, S., Rostami-Hochaghan, A., Galetin, A. & Aarons, L., 2015, In : Pharmaceutical Research. 32, 6, p. 1864-1883 19 p., 1573-904X.

    Research output: Contribution to journalArticle

  8. 2014
  9. Published
  10. Published

    A physiologically based pharmacokinetic model for Valproic acid in adults and children.

    Ogungbenro, K., Aarons, L., Bajard, A., Ballot, C., Bertrand, Y., Bretz, F., Caudri, D., Castellan, C., Chabaud, S., Cornu, C., Dufour, F., Eymard, N., Fisch, R., Guerrini, R., Jullien, V., Kassaï, B., Nony, P., Pérol, D., Pons, G., Tiddens, H. & 5 othersRosati, A., Alberti, C., Chiron, C., Kurbatova, P. & Nabbout, R., 15 Oct 2014, In : European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 63, p. 45-52 7 p.

    Research output: Contribution to journalArticle

  11. Published

    A Physiologically Based Pharmacokinetic Model for Clobazam and Stiripentol in Adults and Children

    Ogungbenro, K., Aarons, L. & Epi-CRESim Project Groups, 23 Jul 2014, In : Pharmaceutical Research. 32, 1, p. 144-157 13 p.

    Research output: Contribution to journalArticle

  12. Published

    Critical Analysis and Communication: an alternative to the final year project

    Barber, J., Demonacos, C., Aarons, L., Steinke, D. & Tully, M., 30 Jun 2014, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

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