Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. Published

    Population Fisher information matrix and optimal design of discrete data responses in population pharmacodynamic experiments

    Ogungbenro, K. & Aarons, L., Aug 2011, In : Journal of pharmacokinetics and pharmacodynamics. 38, 4, p. 449-469 20 p.

    Research output: Contribution to journalArticle

  2. Published

    Population dynamics of untreated Plasmodium falciparum malaria within the adult human host during the expansion phase of the infection

    Simpson, J. A., Aarons, L., Collins, W. E., Jeffery, G. M. & White, N. J., 2002, In : Parasitology. 124, 3, p. 247-263 16 p.

    Research output: Contribution to journalArticle

  3. Published

    Population approaches/sparse data analysis for human variability in kinetics and dynamics

    Aarons, L., 15 Oct 1996, In : Environmental Toxicology and Pharmacology. 2, 2-3, p. 197-199 2 p.

    Research output: Contribution to journalArticle

  4. Published

    Plasma and tonsillar tissue pharmacokinetics of teicoplanin following intramuscular administration to children

    Aarons, L., Rowland, M., Khan, A., Taborelli, G., Ferrea, G., Tarantino, V., Fioredda, F., Rosina-Parenti, R., Cavenaghi, L. & Borgonovi, M., 1 Oct 1998, In : European Journal of Pharmaceutical Sciences. 6, 4, p. 265-270 5 p.

    Research output: Contribution to journalArticle

  5. Published

    Physiologically-based pharmacokinetic modelling of a homologous series of barbiturates in the rat: A sensitivity analysis

    Nestorov, I. A., Aarons, L. & Rowland, M., Aug 1997, In : Journal of pharmacokinetics and biopharmaceutics. 25, 4, p. 413-449

    Research output: Contribution to journalArticle

  6. Published

    Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate.

    Ogungbenro, K. & Aarons, L., Apr 2014, In : Journal of pharmacokinetics and pharmacodynamics. 41, 2, p. 173-185 12 p.

    Research output: Contribution to journalArticle

  7. Published

    Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 1: methotrexate.

    Ogungbenro, K. & Aarons, L., Apr 2014, In : Journal of pharmacokinetics and pharmacodynamics. 41, 2, p. 159-171 12 p.

    Research output: Contribution to journalArticle

  8. Published

    Physiologically based pharmacokinetic model for 6-mercpatopurine: exploring the role of genetic polymorphism in TPMT enzyme activity.

    Ogungbenro, K., Aarons, L., Bajard, A., Ballot, C., Bertrand, Y., Bretz, F., Caudri, D., Castellan, C., Chabaud, S., Cornu, C., Dufour, F., Eymard, N., Fisch, R., Guerrini, R., Jullien, V., Kassaï, B., Nony, P., Pérol, D., Pons, G., Tiddens, H. & 5 others, Rosati, A., Alberti, C., Chiron, C., Kurbatova, P. & Nabbout, R., Jul 2015, In : British Journal of Clinical Pharmacology. 80, 1

    Research output: Contribution to journalArticle

  9. Published

    Physiologically based pharmacokinetc modeling of a homologous series of barbiturates in the rat. II. A Sensitivity analysis of the model.

    Nestorov, I. A., Aarons, L. & Rowland, M., 1997, In : Journal of pharmacokinetics and biopharmaceutics. 25

    Research output: Contribution to journalArticle

  10. Published

    Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer

    Ranson, M., Dean, E., Jodrell, D., Connolly, K., Danson, S., Jolivet, J., Durkin, J., Morris, S., Jowle, D., Ward, T., Cummings, J., Dickinson, G., Aarons, L., LaCasse, E., Robson, L. & Dive, C., 1 Apr 2009, In : Journal of Clinical Oncology. 27, 10, p. 1660-1666 6 p.

    Research output: Contribution to journalArticle

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