Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. Published

    The effect of cimetidine on the steady-state pharmacokinetics and pharmacodynamics of warfarin in humans

    Niopas, I., Toon, S., Aarons, L. & Rowland, M., 1999, In : European journal of clinical pharmacology. 55, 5, p. 399-404 5 p.

    Research output: Contribution to journalArticle

  2. Published

    The Influence of Normalization Weight in Population Pharmacokinetic Covariate Models

    Goulooze, S. C., Voller, S., Valitalo, P. AJ., Calvier, E. AM., Aarons, L., Krekels, E. HJ. & Knibbe, C. A. J., 2018, In : Clinical Pharmacokinetics.

    Research output: Contribution to journalArticle

  3. Published

    The pharmacokinetics of saquinavir: A Markov chain Monte Carlo population analysis

    Lunn, D. J. & Aarons, L., 1998, In : Journal of pharmacokinetics and biopharmaceutics. 26, 1, p. 47-74 27 p.

    Research output: Contribution to journalArticle

  4. Published

    The Population Approach: Measuring and Managing Variability in Response, Concentration and Dose, Commission of the European Community, Luxembourg

    Aarons, L., Rowland, M., Balant, L. P., Danhof, M., Gex-Fabry, M., Gundert-Remy, U. A., Karlsson, M. O., Mentre, F., Morselli, P. L., Rombout, F., Steimer, J. L. & Vozeh, S., 1997, No publisher name. (proceedings of a meeting, edited by authors and published as a book)

    Research output: Book/ReportAnthology

  5. Published

    The population pharmacokinetics of R- and S-warfarin: Effect of genetic and clinical factors

    Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Park, B. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. & Pirmohamed, M., Jan 2012, In : British Journal of Clinical Pharmacology. 73, 1, p. 66-76 10 p.

    Research output: Contribution to journalArticle

  6. Published

    The use of a modified Fedorov exchange algorithm to optimise sampling times for population pharmacokinetic experiments

    Ogungbenro, K., Graham, G., Gueorguieva, I. & Aarons, L., Nov 2005, In : Computer Methods and Programs in Biomedicine. 80, 2, p. 115-125 10 p.

    Research output: Contribution to journalArticle

  7. Published

    The use of population pharmacokinetics in drug development

    Vozeh, S., Steimer, J. L., Rowland, M., Morselli, P., Mentré, F., Balant, L. P. & Aarons, L., 1996, In : Clinical Pharmacokinetics. 30, 2, p. 81-93 12 p.

    Research output: Contribution to journalArticle

  8. Published

    The Use of ROC Analysis for the Qualitative Prediction of Human Oral Bioavailability from Animal Data

    Olivares-Morales, A., Hatley, O. J. D., Turner, D., Galetin, A., Aarons, L. & Rostami-Hodjegan, A., 27 Sep 2013, In : Pharmaceutical Research. 31, 3, p. 720-730 10 p.

    Research output: Contribution to journalArticle

  9. Published

    Translating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption

    Olivares-Morales, A., Lennernäs, H., Aarons, L. & Rostami-Hodjegan, A., 19 May 2015, In : The A A P S Journal. 17, 5, p. 1177-1192 15 p.

    Research output: Contribution to journalArticle

  10. Published

    Use of nonlinear mixed-effects analysis for improved precision of early pharmacodynamic measures in tuberculosis treatment

    Davies, G. R., Brindle, R., Khoo, S. H. & Aarons, L. J., Sep 2006, In : Antimicrobial Agents and Chemotherapy. 50, 9, p. 3154-3156 2 p.

    Research output: Contribution to journalArticle