Prof Leon AaronsBSc, MSc, PhD

Professor

Full contact details
View graph of relations

Publications

  1. Published

    Comparison of in vivo and in silico methods to predict tissue:plasma partition coefficients in rat

    Graham, H., Jones, O., Galetin, A. & Aarons, L., 25 Nov 2009, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  2. Published

    Combining the "bottom-up" and "top-down" approaches in pharmacokinetic modelling: Fitting PBPK models to observed clinical data

    Tsamandouras, N., Rostami-Hochaghan, A. & Aarons, L., 2015, In : British Journal of Clinical Pharmacology. 79, 1, p. 48-55 7 p.

    Research output: Contribution to journalArticle

  3. Published

    Choosing an optimal input for an intravenous glucose tolerance test to aid parameter identification

    Martin, E., Yates, J. W. T., Ogungbenro, K. & Aarons, L., 5 Sep 2017, In : Journal of Pharmacy and Pharmacology. p. 1-9

    Research output: Contribution to journalArticle

  4. Published

    Can BDDCS Class be used to explain differences in the prediction of human oral bioavailability from animal data using a threshold-based model?

    Olivares Morales, A., Hatley, OJD., Turner, D., Galetin, A., Aarons, L. & Rostami, A., Nov 2013.

    Research output: Contribution to conferencePoster

  5. Published

    Bayesian optimal designs for pharmacokinetic models: Sensitivity to uncertainty

    Dokoumetzidis, A. & Aarons, L., Sep 2007, In : Journal of Biopharmaceutical Statistics. 17, 5, p. 851-867 16 p.

    Research output: Contribution to journalArticle

  6. Published

    Assessment of Nevirapine Prophylactic and Therapeutic Dosing Regimens for Neonates

    Cressey, T. R., Punyawudho, B., Le Coeur, S., Jourdain, G., Saenjum, C., Capparelli, E. V., Jittayanun, K., Phanomcheong, S., Luvira, A., Borkird, T., Puangsombat, A., Aarons, L., Sukrakanchana, P. O., Urien, S., Lallemant, M., Sangsawang, S., Achalapong, J., Preedisripipat, K., Putiyanun, C., Wanchaitanawong, V. & 31 others, Yuthavisuthi, P., Ngampiyaskul, C., Kanjanavikai, P., Chotivanich, N., Hongsiriwon, S., Suwankornsakul, W., Sreshthatat, P., Kanjanasing, A., Kwanchaipanich, R., Rawangban, B., Santadusit, S., Jarupanich, T., Warachit, B., Siriwachirachai, T., Rojanakarin, P., Vivatpatanakul, K., Hanpinitsak, S., Wanasiri, P., Srirojana, S., Kongpanichkul, R., Bunjongpak, S., Sabsanong, P., Liampongsabuddhi, P., Pongdetudom, K., Khamja, P., Akarathum, N., Phonin, S. A., Limpitikul, W., Jungpipun, J., Petprakorp, R. & The PHPT-5 study team, 15 Aug 2017, In : Journal of Acquired Immune Deficiency Syndromes. 75, 5, p. 554-560 7 p.

    Research output: Contribution to journalArticle

  7. Published

    Application of optimal design methodologies in clinical pharmacology experiments

    Ogungbenro, K., Dokoumetzidis, A. & Aarons, L., Jul 2009, In : Pharmaceutical Statistics. 8, 3, p. 239-252 13 p.

    Research output: Contribution to journalArticle

  8. Published

    Application of a Bayesian approach to physiological modelling of mavoglurant population pharmacokinetics

    Wendling, T., Dumitras, S., Ogungbenro, K. & Aarons, L., 1 Aug 2015, In : Journal of pharmacokinetics and pharmacodynamics. 42, 6, p. 639-657 18 p.

    Research output: Contribution to journalArticle

  9. Published

    Analytical expressions for combining population pharmacokinetic parameters from different studies

    Dokoumetzidis, A. & Aarons, L., Jul 2008, In : Journal of Biopharmaceutical Statistics. 18, 4, p. 662-676 14 p.

    Research output: Contribution to journalArticle

  10. Published

    Analysis of the impact of controlled release formulation on oral drug absorption, gut wall metabolism and relative bioavailability of CYP3A substrates using a physiologically-based pharmacokinetic model

    Olivares-Morales, A., Kamiyama, Y., Darwich, A. S., Aarons, L. & Rostami, A., 25 Jan 2015, In : European Journal of Pharmaceutical Sciences. 67, p. 32-44 12 p.

    Research output: Contribution to journalArticle