Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. Published

    Propagation of population PK and PD information using a Bayesian approach: Dealing with non-exchangeability

    Dokoumetzidis, A. & Aarons, L., Feb 2006, In : Journal of pharmacokinetics and pharmacodynamics. 33, 1, p. 29-48 19 p.

    Research output: Contribution to journalArticle

  2. Published

    Qualitative model for the prediction of high/low human oral bioavailability from animal bioavailability data employing ROC analysis

    Olivares Morales, A., Hatley, OJD., Turner, D., Galetin, A., Aarons, L. & Rostami, A., Jun 2013.

    Research output: Contribution to conferencePoster

  3. Published

    Qualitative model for the prediction of high/low human oral bioavailability from animal bioavailability data employing ROC analysis

    Olivares-Morales, A., Hatley, OJD., Turner, D., Galetin, A., Aarons, L. & Rostami, A., Nov 2013.

    Research output: Contribution to conferencePoster

  4. Published

    Qualitative prediction of human oral bioavailability from animal oral bioavailability data employing ROC analysis

    Olivares Morales, A., Hatley, OJD., Turner, D., Galetin, A., Aarons, L. & Rostami, A., 14 Jun 2013.

    Research output: Contribution to conferencePoster

  5. Published

    Quantitative characterization of therapeutic index: Application of mixed-effects modeling to evaluate oxybutynin dose-efficacy and dose-side effect relationships

    Gupta, S. K., Sathyan, G., Lindemulder, E. A., Ho, P. L., Sheiner, L. B. & Aarons, L., 1999, In : Clinical Pharmacology and Therapeutics. 65, 6, p. 672-684 12 p.

    Research output: Contribution to journalArticle

  6. Published

    Quantitative structure-pharmacokinetic relationships. I. Development of a whole body physiologically based model to characterise changes in pharmacokinetics across a homologous series of barbiturates in the rat.

    Blakey, G. M., Al, N. I., Arundel, P. A., Aarons, L. & Rowland, M., 1997, In : J. Pharmaco. Biopharm.. 25 (3)

    Research output: Contribution to journalArticle

  7. Published

    Quantitative structure-pharmacokinetics relationships II. Mechanistically based model for the relationship between the tissue distribution parameters and the lipophilicity of the compounds.

    Nestorov, I., Aarons, L. & Rowland, M., Oct 1998, In : Journal of pharmacokinetics and biopharmaceutics. 26, 5, p. 521-545

    Research output: Contribution to journalArticle

  8. Published

    Ratifying the dosage and duration of levo-bupivacaine infusion by the caudal-epidural route in infants aged three to six months

    Vashisht, R., Bendon, A., Okonkwo, I., Darwich, A. & Aarons, L., May 2018, In : British Journal of Anaesthesia. 120, p. e11-e12 2 p.

    Research output: Contribution to journalMeeting Abstract

  9. Published

    Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data.

    Wendling, T., Tsamandouras, N., Dumitras, S., Pigeolet, E., Ogungbenro, K. & Aarons, L., 4 Nov 2015, In : The AAPS journal. 18, 1

    Research output: Contribution to journalArticle

  10. Published

    Retrospective population pharmacokinetic analysis of cetirizine in children aged 6 months to 12 years

    Pitsiu, M., Hussein, Z., Majid, O., Aarons, L., De Longueville, M. & Stockis, A., Apr 2004, In : British Journal of Clinical Pharmacology. 57, 4, p. 402-411 9 p.

    Research output: Contribution to journalArticle