Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. Published

    Methodological approaches to the population analysis of toxicity data

    Aarons, L. & Graham, G., 31 Mar 2001, In : Toxicology Letters. 120, 1-3, p. 405-410 5 p.

    Research output: Contribution to journalArticle

  2. Published

    Pharmacodynamics of controlled release verapamil in patients with hypertension: An analysis using spline functions

    Aarons, L., Baxter, C. & Gupta, S., Jul 2004, In : Biopharmaceutics and Drug Disposition. 25, 5, p. 219-225 6 p.

    Research output: Contribution to journalArticle

  3. Published

    Editorial: Pharmacokinetic and pharmacodynamic modelling in drug development

    Aarons, L., Jun 1999, In : Statistical Methods in Medical Research. 8, 3, p. 181-182

    Research output: Contribution to journalArticle

  4. Published

    COST B15: modelling in drug development

    Aarons, L., Balant, L. & Boobis, A., Jul 2001, In : British Journal of Clinical Pharmacology. 52, 1, p. 118-119

    Research output: Contribution to journalArticle

  5. Published

    Optimal design of pharmacokinetic studies

    Aarons, L. & Ogungbenro, K., Mar 2010, In : Basic and Clinical Pharmacology and Toxicology. 106, 3, p. 250-255 5 p.

    Research output: Contribution to journalArticle

  6. Published

    Estimation of population pharmacokinetic parameters of free-phenytoin in adult epileptic patients

    Aarons, L., Ahmed, I. A. & Deleu, D., Jan 2005, In : Archives of Medical Research. 36, 1, p. 49-53 4 p.

    Research output: Contribution to journalArticle

  7. Published

    Plasma and tonsillar tissue pharmacokinetics of teicoplanin following intramuscular administration to children

    Aarons, L., Rowland, M., Khan, A., Taborelli, G., Ferrea, G., Tarantino, V., Fioredda, F., Rosina-Parenti, R., Cavenaghi, L. & Borgonovi, M., 1 Oct 1998, In : European Journal of Pharmaceutical Sciences. 6, 4, p. 265-270 5 p.

    Research output: Contribution to journalArticle

  8. Published

    Role of modelling and simulation in Phase I drug development

    Aarons, L., Karlsson, M. O., Mentre, F., Rombout, F., Steimer, J. L. & Van Peer, A., 2001, In : European Journal of Pharmaceutical Sciences. 13, 2, p. 115-122 7 p.

    Research output: Contribution to journalArticle

  9. Published

    Software for population pharmacokinetics and pharmacodynamics

    Aarons, L., 1999, In : Clinical Pharmacokinetics. 36, 4, p. 255-264 9 p.

    Research output: Contribution to journalArticle

  10. Published

    "Population modelling". In: Variability in Human Drug Response. Proceedings of the Esteve Foundation Symposium VIII.

    Aarons, L., 1999, In : Excerpta Medica, Amsterdam.

    Research output: Contribution to journalArticle

  11. Published

    Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies

    Aarons, L., Rowland, M., Balant, L. P., Mentré, F., Morselli, P. L., Steimer, J. L. & Vozeh, S., Jan 1996, European Journal of Clinical Pharmacology|Eur J Clin Pharmacol. Springer Nature, Vol. 49. p. 251-254 3 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  12. Published

    Mixed effects modelling of toxicokinetic data

    Aarons, L., 2002, In : The Toxicologist. 66 (1-S)

    Research output: Contribution to journalArticle

  13. Published

    The Population Approach: Measuring and Managing Variability in Response, Concentration and Dose, Commission of the European Community, Luxembourg

    Aarons, L., Rowland, M., Balant, L. P., Danhof, M., Gex-Fabry, M., Gundert-Remy, U. A., Karlsson, M. O., Mentre, F., Morselli, P. L., Rombout, F., Steimer, J. L. & Vozeh, S., 1997, No publisher name. (proceedings of a meeting, edited by authors and published as a book)

    Research output: Book/ReportAnthology

  14. Published

    Population pharmacokinetic analysis of ropivacaine and its metabolite 2′,6′-pipecoloxylidide from pooled data in neonates, infants, and children

    Aarons, L., Sadler, B., Pitsiu, M., Sjövall, J., Henriksson, J. & Molnár, V., Sep 2011, In : British Journal of Anaesthesia. 107, 3, p. 409-424 15 p.

    Research output: Contribution to journalArticle

  15. Published

    Population approaches/sparse data analysis for human variability in kinetics and dynamics

    Aarons, L., 15 Oct 1996, In : Environmental Toxicology and Pharmacology. 2, 2-3, p. 197-199 2 p.

    Research output: Contribution to journalArticle

  16. Published

    An identifiability analysis of a parent-metabolite pharmacokinetic model for ivabradine

    Adams, N. D., Godfrey, K. R., Chapman, M. J., Chappell, M. J., Aarons, L. & Duffull, S. B., 2001, In : Journal of pharmacokinetics and pharmacodynamics. 28, 1, p. 93-105 12 p.

    Research output: Contribution to journalArticle

  17. Published

    Critical Analysis and Communication: an alternative to the final year project

    Barber, J., Demonacos, C., Aarons, L., Steinke, D. & Tully, M., 30 Jun 2014, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  18. Published

    Quantitative structure-pharmacokinetic relationships. I. Development of a whole body physiologically based model to characterise changes in pharmacokinetics across a homologous series of barbiturates in the rat.

    Blakey, G. M., Al, N. I., Arundel, P. A., Aarons, L. & Rowland, M., 1997, In : J. Pharmaco. Biopharm.. 25 (3)

    Research output: Contribution to journalArticle

  19. Published

    A population pharmacokinetic model for doxorubicin and doxorubicinol in the presence of a novel MDR modulator, zosuquidar trihydrochloride (LY335979)

    Callies, S., De Alwis, D. P., Wright, J. G., Sandler, A., Burgess, M. & Aarons, L., 1 Feb 2003, In : Cancer Chemotherapy and Pharmacology. 51, 2, p. 107-118 11 p.

    Research output: Contribution to journalArticle

  20. Published

    Population pharmacokinetic model for daunorubicin and daunorubicinol coadministered with zosuquidar.3HCI (LY335979)

    Callies, S., De Alwis, D. P., Mehta, A., Burgess, M. & Aarons, L., Jul 2004, In : Cancer Chemotherapy and Pharmacology. 54, 1, p. 39-48 9 p.

    Research output: Contribution to journalArticle

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