Prof Leon AaronsBSc, MSc, PhD

Professor

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Publications

  1. Published

    Physiologically based pharmacokinetc modeling of a homologous series of barbiturates in the rat. II. A Sensitivity analysis of the model.

    Nestorov, I. A., Aarons, L. & Rowland, M., 1997, In : Journal of pharmacokinetics and biopharmaceutics. 25

    Research output: Contribution to journalArticle

  2. Published

    Lumping of whole-body physiologically based pharmacokinetic models

    Nestorov, I. A., Aarons, L. J., Arundel, P. A. & Rowland, M., 1998, In : Journal of pharmacokinetics and biopharmaceutics. 26, 1, p. 21-46 25 p.

    Research output: Contribution to journalArticle

  3. Published

    Computer-assisted clinical trial simulation: a phase II case study with naraptriptan

    Nestorov, I., Graham, G., Duffell, S., Aarons, L., Fuseau, E. & Coates, P., 2001, In : Pharmacol. Toxicol.. 89 (suppl. 1)

    Research output: Contribution to journalArticle

  4. Published

    Physiologically-based pharmacokinetic modelling of a homologous series of barbiturates in the rat: A sensitivity analysis

    Nestorov, I. A., Aarons, L. & Rowland, M., Aug 1997, In : Journal of pharmacokinetics and biopharmaceutics. 25, 4, p. 413-449

    Research output: Contribution to journalArticle

  5. Published

    A mechanistically based model for the relationship between the tissue distribution parameters and the lipophilicity of a homologous series of barbiturates in rats

    Nestorov, I., Aarons, L. & Rowland, M., 1999, Eur. J. Pharm. Sci.. Vol. 8.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  6. Published

    Modeling and simulation for clinical trial design involving a categorical response: A phase ii case study with naratriptan

    Nestorov, I., Graham, G., Duffull, S., Aarons, L., Fuseau, E. & Coates, P., 2001, In : Pharmaceutical Research. 18, 8, p. 1210-1219 9 p.

    Research output: Contribution to journalArticle

  7. Published

    A physiologically-based pharmacokinetic model for the distribution of barbiturates in rats. AAPS Tenth Anniversary Meeting, 27-31 October 1996, Seattle, Washington

    Nestorov, I., Blakey, G. A., Arundel, P. A., Aarons, L. & Rowland, M., 1996, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  8. Published

    Quantitative structure-pharmacokinetics relationships II. Mechanistically based model for the relationship between the tissue distribution parameters and the lipophilicity of the compounds.

    Nestorov, I., Aarons, L. & Rowland, M., Oct 1998, In : Journal of pharmacokinetics and biopharmaceutics. 26, 5, p. 521-545

    Research output: Contribution to journalArticle

  9. Published

    The effect of cimetidine on the steady-state pharmacokinetics and pharmacodynamics of warfarin in humans

    Niopas, I., Toon, S., Aarons, L. & Rowland, M., 1999, In : European journal of clinical pharmacology. 55, 5, p. 399-404 5 p.

    Research output: Contribution to journalArticle

  10. Published

    Design of Population Pharmacokinetic Studies: Sample size Determination

    Ogungbenro, K., Graham, G. & Aarons, L., Jun 2004.

    Research output: Contribution to conferencePoster

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