Prof Leon Aarons BSc, MSc, PhD

Professor

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Publications

  1. 2020
  2. E-pub ahead of print

    Intravitreal pharmacokinetic study of the anti-angiogenic glycoprotein opticin

    Del Amo, E. M., Griffiths, J. R., Klaska, I. P., Hoke, J., White, A., Aarons, L., Cooper, G. J. S., Bainbridge, J. W. B., Bishop, P. N. & Unwin, R. D., 21 May 2020, In : Molecular Pharmaceutics.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Impact of tumour size measurement inter‑operator variability on model‑based drug effect evaluation

    Lombard, A., Mistry, H., Chapman, S. C., Gueoguieva, I., Aarons, L. & Ogungbenro, K., 13 Mar 2020, In : Cancer Chemotherapy and Pharmacology. 9 p., 10.1007/s00280-020-04049-5.

    Research output: Contribution to journalArticlepeer-review

  4. E-pub ahead of print

    Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue Distribution

    Yau, E., Olivares-Morales, A., Gertz, M., Parrott, N., Darwich, A. S., Aarons, L. & Ogungbenro, K., 3 Feb 2020, In : The AAPS journal. 22, 2, p. 41

    Research output: Contribution to journalArticlepeer-review

  5. 2019
  6. Published

    Variance based global sensitivity analysis of physiologically based pharmacokinetic absorption models for BCS I–IV drugs

    Melillo, N., Aarons, L., Magni, P. & Darwich, A. S., 15 Feb 2019, In : Journal of pharmacokinetics and pharmacodynamics. 46, 1, p. 27-42 16 p.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    A Study of the dosage and duration for levobupivacaine infusion by the caudal-epidural route in infants aged 3-6 months

    Vashisht, R., Bendon, A., Okonkwo, I., Patel, D., Fullwood, C., Ogungbenro, K., Aarons, L. & Darwich, A., 1 Feb 2019, In : Pediatric Anesthesia. 29, 2, p. 161-168 8 p.

    Research output: Contribution to journalArticlepeer-review

  8. 2018
  9. Published

    Establishment and validation of microsampling techniques in wild rodents for ecotoxicological research

    Imholt, C., Abdulla, T., Stevens, A., Edwards, P., Jacob, J., Woods, D., Rogers, E., Aarons, L. & Segelcke, D., Sep 2018, In : Journal of Applied Toxicology. 38, 9

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Ratifying the dosage and duration of levo-bupivacaine infusion by the caudal-epidural route in infants aged three to six months

    Vashisht, R., Bendon, A., Okonkwo, I., Darwich, A. & Aarons, L., May 2018, In : British Journal of Anaesthesia. 120, p. e11-e12 2 p.

    Research output: Contribution to journalMeeting Abstractpeer-review

  11. Published

    Pharmacodynamic modelling of resistance to epidermal growth factor receptor inhibition in brain metastasis mouse models.

    Martin, E., Aarons, L. & Yates, J. W. T., 2018, In : Cancer Chemotherapy and Pharmacology.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    The Influence of Normalization Weight in Population Pharmacokinetic Covariate Models

    Goulooze, S. C., Voller, S., Valitalo, P. AJ., Calvier, E. AM., Aarons, L., Krekels, E. HJ. & Knibbe, C. A. J., 2018, In : Clinical Pharmacokinetics.

    Research output: Contribution to journalArticlepeer-review

  13. 2017
  14. Published

    Whole body physiologically based modelling of β-blockers in the rat: events in tissues and plasma following an i.v. bolus dose

    Cheung, S. Y. A. ., Rodgers, T., Aarons, L., Gueorguieva, I., Dickinson, G. L., Murby, S., Brown, C., Collins, B. & Rowland, M., 22 Dec 2017, In : British Journal of Pharmacology . p. 1 17 p.

    Research output: Contribution to journalArticlepeer-review

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