Dr Kieron South

Research Fellow

Affiliations:
Links:
ORCID: 0000-0002-9141-3438
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Publications

1 - 10 out of 13Page size: 10
  1. 2020
  2. Published

    Severity-stratified and longitudinal analysis of VWF/ADAMTS13 imbalance, altered fibrin crosslinking and inhibition of fibrinolysis as contributors to COVID-19 coagulopathy

    CIRCO, 21 Aug 2020, medRxiv, (medRxiv).

    Research output: Working paper

    DOI: 10.1101/2020.08.18.20159608
  3. Published

    Severity-stratified and longitudinal analysis of VWF/ADAMTS13 imbalance, altered fibrin crosslinking and inhibition of fibrinolysis as contributors to COVID-19 coagulopathy

    South, K., Mann, E., Menon, M., Konkel, JE., Ustianowsk, A., Bakerly, ND., Dark, PM., Felton, T., Horsley, A., Hussell, T., CIRCO, Roberts, L., Morris, L., Knight, S. B., Grainger, J. R., Smith, C. J. & Allan, S. M., 1 Aug 2020, 22 p.

    Research output: Other contribution › peer-review

    DOI: 10.1101/2020.08.18.20159608
  4. E-pub ahead of print

    Preceding Infection and Risk of Stroke: An Old Concept Revived by the COVID-19 Pandemic

    South, K., Allan, S. & Smith, C., 24 Jul 2020, (E-pub ahead of print) In: International Journal of Stroke. 10.1177/1747493020943815.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1177/1747493020943815
  5. 2019
  6. Published

    The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

    Newnham, M., South, K., Bleda, M., Auger, W. R., Barberà, J. A., Bogaard, H., Bunclark, K., Cannon, J. E., Delcroix, M., Hadinnapola, C., Howard, L. S., Jenkins, D., Mayer, E., Ng, C., Rhodes, C. J., Screaton, N., Sheares, K., Simpson, M. A., Southwood, M., Su, L. & 12 others, Taboada, D., Traylor, M., Trembath, R. C., Villar, S. S., Wilkins, M. R., Wharton, J., Gräf, S., Pepke-Zaba, J., Laffan, M., Lane, D. A., Morrell, N. W. & Toshner, M., 2019, In: The European respiratory journal. 53, 3

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1183/13993003.01805-2018
  7. 2018
  8. Published

    Enhanced activity of an ADAMTS-13 variant (R568K/F592Y/R660K/Y661F/Y665F) against platelet agglutination in vitro and in a murine model of acute ischemic stroke

    South, K., Denorme, F., Salles-crawley, I. I., De Meyer, S. F. & Lane, D. A., Nov 2018, In: Journal of Thrombosis and Haemostasis. 16, 11, p. 2289-2299 11 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1111/jth.14275
  9. Published

    ADAMTS-13 and von Willebrand factor: a dynamic duo

    South, K. & Lane, D. A., 1 Jan 2018, In: Journal of thrombosis and haemostasis : JTH. 16, 1, p. 6-18 13 p.

    Research output: Contribution to journal › Review article › peer-review

    DOI: 10.1111/jth.13898
  10. 2017
  11. Published

    A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor

    South, K., Freitas, M. O. & Lane, D. A., 7 Apr 2017, In: The Journal of biological chemistry. 292, 14, p. 5760-5769 10 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1074/jbc.M117.776732
  12. Published

    Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

    Athanasiou, D., Aguila, M., Opefi, C. A., South, K., Bellingham, J., Bevilacqua, D., Munro, P. M., Kanuga, N., Mackenzie, F. E., Dubis, A. M., Georgiadis, A., Graca, A. B., Pearson, R. A., Ali, R. R., Sakami, S., Palczewski, K., Sherman, M. Y., Reeves, P. J. & Cheetham, M. E., 15 Jan 2017, In: Human Molecular Genetics. 26, 2, p. 305-319 15 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1093/hmg/ddw387
  13. 2016
  14. Published

    Conformational quiescence of ADAMTS-13 prevents proteolytic promiscuity

    South, K., Freitas, M. O. & Lane, D. A., 27 Oct 2016, In: Journal of thrombosis and haemostasis : JTH. 14, 10, p. 2011-2022 12 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1111/jth.13445
  15. 2014
  16. Published

    Conformational activation of ADAMTS13

    South, K., Luken, B. M., Crawley, J. T. B., Thomas, M., Collins, R. F., Deforche, L., Vanhoorelbeke, K. & Lane, D. A., 30 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 52, p. 18578-18583 6 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1073/pnas.1411979112
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Publications highlights

Enhanced activity of an ADAMTS-13 variant (R568K/F592Y/R660K/Y661F/Y665F) against platelet agglutination in vitro and in a murine model of acute ischemic stroke

Research output: Contribution to journal › Article › peer-review

ADAMTS-13 and von Willebrand factor: a dynamic duo

Research output: Contribution to journal › Review article › peer-review

Conformational activation of ADAMTS13

Research output: Contribution to journal › Article › peer-review

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

Research output: Contribution to journal › Article › peer-review

Highly conserved tyrosine stabilizes the active state of rhodopsin

Research output: Contribution to journal › Article › peer-review

Research Explorer downloads

10
Preceding Infection and Risk of Stroke: An Old Concept Revived by the COVID-19 Pandemic

Research output: Contribution to journal › Article › peer-review