Dr Katherine Kellett

Research Fellow and Lab Manager

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Publications

  1. 2016
  2. Published

    Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia

    Xu, J., Begley, P., Church, S., Patassini, S., Mcharg, S., Kureishy, N., Hollywood, K., Waldvogel, H. J., Liu, H., Zhang, S., Lin, W., Herholz, K., Turner, C., Synek, B. J., Curtis, M. A., Rivers-Auty, J., Lawrence, C., Kellett, K., Hooper, N., Vardy, E. R. L. C. & 5 others, Wu, D., Unwin, R., Faull, R. L. M., Dowsey, A. & Cooper, G., 2016, In : Scientific Reports. 6, 27524 .

    Research output: Contribution to journalArticle

  3. Published

    Ablation of prion protein in wild type human amyloid precursor protein (APP) transgenic mice does not alter the proteolysis of APP, levels of amyloid-β or pathologic phenotype

    Whitehouse, I. J., Brown, D., Baybutt, H., Diack, A. B., Kellett, K., Piccardo, P., Manson, J. C. & Hooper, N., 22 Jul 2016, In : PLoS ONE. 11, 7, e0159119.

    Research output: Contribution to journalArticle

  4. Published

    A Greek Tragedy: the Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis

    Andrew, R. J., Kellett, K., Thinakaran, G. & Hooper, N., 9 Sep 2016, In : Journal of Biological Chemistry. 291, p. 19235-19244 10 p.

    Research output: Contribution to journalArticle

  5. 2018
  6. Published

    Modelling Sporadic Alzheimer’s Disease using Induced Pluripotent Stem Cells

    Rowland, H., Hooper, N. & Kellett, K., 2018, In : Neurochemical research.

    Research output: Contribution to journalArticle

  7. Published

    Tau proteolysis in the pathogenesis of tauopathies: neurotoxic fragments and novel biomarkers

    Quinn, J., Corbett, N., Kellett, K. & Hooper, N., 2018, In : Journal of Alzheimer's Disease. 63, 1, p. 13-33 20 p.

    Research output: Contribution to journalArticle

  8. Published

    Plasma metals as potential biomarkers in dementia: a case–control study in patients with sporadic Alzheimer’s disease

    Xu, J., Church, S. J., Patassini, S., Begley, P., Kellett, K. A. B., Vardy, E. R. L. C., Unwin, R. D., Hooper, N. M. & Cooper, G. J. S., Apr 2018, In : BioMetals. 31, 2, p. 267-276 10 p.

    Research output: Contribution to journalArticle

  9. Published

    Tau pathology and neurochemical changes associated with memory dysfunction in an optimised murine model of global cerebral ischaemia - A potential model for vascular dementia?

    Khan, S., Yuldasheva, N. Y., Batten, T. F. C., Pickles, A. R., Kellett, K. A. B. & Saha, S., Sep 2018, In : Neurochemistry International. 118, p. 134-144

    Research output: Contribution to journalArticle

  10. 2019
  11. Published

    Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers

    Jarosz-griffiths, H. H., Corbett, N. J., Rowland, H. A., Fisher, K., Jones, A. C., Baron, J., Howell, G. J., Cowley, S. A., Chintawar, S., Cader, M. Z., Kellett, K. A. B. & Hooper, N. M., 2019, In : Journal of Biological Chemistry. p. jbc.RA118.005364

    Research output: Contribution to journalArticle

  12. Published

    Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms

    Andrew, R. J., Fisher, K., Heesom, K. J., Kellett, K. A. B. & Hooper, N. M., 14 Feb 2019, In : Journal of neurochemistry.

    Research output: Contribution to journalArticle

  13. Published

    Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake

    Banerjee, S., Andrew, R. J., Duff, C. J., Fisher, K., Jackson, C. D., Lawrence, C. B., Maeda, N., Greenspan, D. S., Kellett, K. & Hooper, N., 6 Aug 2019, In : Scientific Reports.

    Research output: Contribution to journalArticle