Prof Jason Micklefield PhD

Professor of Chemical Biology

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Publications

  1. 2020
  2. Published

    Engineering Escherichia coli towards de novo production of gatekeeper (2S)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol.

    Dunstan, M., Robinson, C., Jervis, A., Yan, C., Carbonell, P., Hollywood, K., Currin, A., Swainston, N., Le Feuvre, R., Micklefield, J., Faulon, J-L., Breitling, R., Turner, N., Takano, E. & Scrutton, N., 6 Aug 2020, In: Synthetic Biology . 5, 1, ysaa012.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Rapid prototyping of microbial production strains for the biomanufacture of potential material monomers

    Robinson, C., Carbonell, P., Jervis, A., Yan, C., Hollywood, K., Currin, A., Swainston, N., Speiss, R., Taylor, S., Mulherin, P., Parker, S., Rowe, W., Matthews, N., Malone, K., Le Feuvre, R., Shapira, P., Barran, P., Turner, N., Micklefield, J., Breitling, R. & 2 others, Takano, E. & Scrutton, N., 1 Jul 2020, In: Metabolic Engineering.

    Research output: Contribution to journalArticlepeer-review

  4. E-pub ahead of print

    Engineering orthogonal methyltransferases to create alternative bioalkylation pathways.

    Herbert, A. J., Shepherd, S. A., Cronin, V. A., Bennett, M. R., Sung, R. & Micklefield, J., 13 May 2020, In: Angewandte Chemie International Edition.

    Research output: Contribution to journalArticlepeer-review

  5. E-pub ahead of print

    Harnessing and Engineering Amide Bond Forming Ligases for the Synthesis of Amides

    Winn, M., Richardson, S., Campopiano, D. J. & Micklefield, J., 12 Feb 2020, In: Current Opinion in Chemical Biology.

    Research output: Contribution to journalArticlepeer-review

  6. 2019
  7. Published

    Engineering Enzymatic Assembly Lines to Produce New Antibiotics.

    Micklefield, J., 16 Nov 2019, In: Current Opinion in Microbiology. 51, p. 88-96 9 p.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Streamlined recycling of S-adenosylmethionine

    Micklefield, J., 8 Jul 2019, In: Nature Catalysis.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli

    Cummings, M., Peters, A., Whitehead, G., Menon, B., Micklefield, J., Webb, S. & Takano, E., 2019, In: PL o S Biology.

    Research output: Contribution to journalArticlepeer-review

  10. 2018
  11. Published

    Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase

    Bennett, M., Thompson, M., Levy, C., Menon, B., Cronin, V., Smith, D., Herbert, A., Dunstan, M., Shepherd, S. & Micklefield, J., 13 Aug 2018, In: Angewandte Chemie - International Edition. 57, 33, p. 10600-10604 5 p.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    De novo Biosynthesis of 'Non‐Natural' Thaxtomin Phytotoxins

    Winn, M., Francis, D. & Micklefield, J., 25 May 2018, In: Angewandte Chemie - International Edition. 57, 23, p. 6830-6833 4 p.

    Research output: Contribution to journalArticlepeer-review

  13. Published

    The cycloaspeptides: Uncovering a new model for methylated nonribosomal peptide biosynthesis

    De Mattos-Shipley, K. M. J., Greco, C., Heard, D. M., Hough, G., Mulholland, N. P., Vincent, J. L., Micklefield, J., Simpson, T. J., Willis, C. L., Cox, R. J. & Bailey, A. M., 10 Apr 2018, In: Chemical Science. 9, 17, p. 4109-4117 9 p.

    Research output: Contribution to journalArticlepeer-review

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