Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. 1983
  2. Published

    Absorption of prednisolone in patients with Crohn's disease

    Shaffer, J. A., Williams, S. E., Turnberg, L. A., Houston, J. & Rowland, M., Mar 1983, In : Gut. 24, 3, p. 182-6 5 p.

    Research output: Contribution to journalArticle

  3. Published

    Pharmacokinetics of promethazine and its sulphoxide metabolite after intravenous and oral administration to man

    Taylor, G., Houston, J. B., Shaffer, J. & Mawer, G., Mar 1983, In : British Journal of Clinical Pharmacology. 15, 3, p. 287-93 7 p.

    Research output: Contribution to journalArticle

  4. 1985
  5. Published

    The effect of rifampicin on sulphapyridine plasma concentrations following sulphasalazine administration

    Shaffer, J. L. & Houston, J. B., Apr 1985, In : British Journal of Clinical Pharmacology. 19, 4, p. 526-8 3 p.

    Research output: Contribution to journalArticle

  6. 1986
  7. Published

    Disposition of metronidazole and its effects on sulphasalazine metabolism in patients with inflammatory bowel disease

    Shaffer, J. L., Kershaw, A. & Houston, J. B., Apr 1986, In : British Journal of Clinical Pharmacology. 21, 4, p. 431-5 5 p.

    Research output: Contribution to journalArticle

  8. 1994
  9. Published

    Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance’, Biochemical Pharmacology

    Houston, JB., 1994, In : Biochemical Pharmacology. 47, p. 1469-1479 10 p.

    Research output: Contribution to journalArticle

  10. 1996
  11. Published
  12. Published

    Diazepam-omepazole inhibition interaction: An in vitro investigation using human liver microsomes.

    Zomorodi, K. & Houston, B., 1996, In : Br. J. Clin. Pharmacol.. 42

    Research output: Contribution to journalArticle

  13. Published

    Effect of aminobenzotraizole on diazepam metabolism, Stoke Rochford.

    Hakooz, N. & Houston, B., 1996, 6th Stowe Symposium on Drug Metabolism.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  14. Published

    Kinetics of CYP2D6 and CYP3A4 catalyzed reactions in heterologous expression systems

    Randolph, N., Andrews, J., Chenery, R. & Houston, B., 1996, ISSX Proceedings. Vol. 10.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  15. Published

    Kinetics of drug metabolism in rat liver II. Comparison of clearance by slices and isolated hepatocytes.

    Worboys, P. D., Bradbury, A. & Houston, B., 1996, In : Drug Metab. Dispos.. 24

    Research output: Contribution to journalArticle

  16. Published

    Metabolism of midazolam in various expression systems for human CYP3A4.

    Randolph, N., Andrews, J., Chenery, R. & Houston, B., 1996, 6th Stowe Symposium, Stoke Rochford.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  17. Published

    Metabolism of ondansetron in rat. Comparison of hepatic microsomes, isolated hepatocytees and liver slices with in vivo disposition.

    Worboys, P. D., Bradbury, A. & Houston, B., 1996, In : Xenobiotica. 26

    Research output: Contribution to journalArticle

  18. Published

    Predicting the pharmacokinetics of CYP2C9 substrates in man from in vitro studies. Stoke, Rochford

    Carlile, D., Bayliss, M. K., Tarbit, M. H. & Houston, B., 1996, 6th Stowe Symposium on Drug Metabolism.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  19. Published

    Prediction of in vivo intrinsic clearance of ethoxycoumarin using drug depletion data from freshly isolated hepatocytes, Stoke Rochford

    Stevens, A. J. & Houston, B., 1996, 6th Stowe Symposium.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  20. Published

    The metabolism of diazepam, phenytoin, p-nitrophenol and coumarin by pig hepatic microsomes.

    Witherow, LL. E. & Houston, B., 1996, 6th Stowe Symposium.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  21. Published

    Characteristics of nonlinear uptake of lipophilic amine drugs into isolated rat hepatocytes.

    Hallifax, D., Smith, D. A. & Houston, B., Jul 1996.

    Research output: Contribution to conferencePoster

  22. Published

    The Use of Biokinetics and In Vitro Methods in Toxicological Risk Evaluation: The Report and Recommendations of ECVAM Workshop 15

    Blaauboer, B. J., Bayliss, M. K., Castell, J. V., Evelo, C. T. A., Frazier, J. M., Groen, K., Gülden, M., Guillouzo, A., Hissink, A. M., Houston, J. B., Johanson, G., De Jongh, J., Kedderis, G. L., Reinhardt, C. A., Van De Sandt, J. J. M. & Semino, G., Jul 1996, In : Alternatives to Laboratory Animals . 24, 4, p. 473-497 24 p.

    Research output: Contribution to journalArticle

  23. 1997
  24. Published

    Microsomal prediction of intrinsic clearance for CYP2C9 substrates in man: Importance of Km.

    Carlile, DD. & Houston, B., 1997, ISSX Proceedings. Vol. 11.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  25. Published
  26. Published

    Pharmacokinetics in early drug discovery. The report recommendations of ECVAM Workshop 22.

    Leahy, D. E., Duncan, R., Ahr, H. J., Bayliss, M. K., de Boer, A. G., Darvas, F., Fentem, J. H., Fry, J. R., Hopkins, R., Houston, B., Karlsson, J., Kedderis, G. L., Pratten, M. K., Prieto, P., Smith, D. A. & Straughan, D. W., 1997, In : ATLA. 26

    Research output: Contribution to journalArticle

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