Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. 2009
  2. Published

    . Physiologically-Based Pharmacokinetic Modelling of Hepatic Uptake of Pravastatin and Rosuvastatin

    Galetin, A., Houston, JB., Tate, S. & Jones, HM., 25 Nov 2009, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  3. Published

    Assessment of Algorithms for Predicting Drug-Drug Interactions via Inhibition Mechanisms.

    Rostami-Hochaghan, A., Guest, EJ., Rowland, Y. K., Rostami-Hodjegan, A., Tucker, GT., Houston, JB. & Galetin, A., 23 Sep 2009, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  4. Published

    Transporters and cytochrome P450 interplay in defining hepatic drug clearance

    Houston, JB., Sep 2009.

    Research output: Contribution to conferenceOther

  5. Published

    Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption

    Badhan, R., Penny, J., Galetin, A. & Houston, J. B., Jun 2009, In : Journal of Pharmaceutical Sciences. 98, 6, p. 2180-2197 17 p.

    Research output: Contribution to journalArticle

  6. Published

    How good is prediction of in vivo metabolic clearance from established in vitro systems?

    Foster, JA., Hallifax, D. & Houston, B., 17 May 2009.

    Research output: Contribution to conferencePoster

  7. Published

    Involvement of drug uptake in hepatic clearance

    Jigorel, EE. & Houston, B., 17 May 2009, Drug Metab Rev. Vol. Rev 41 (Suppl 1).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  8. Published

    Evaluation of recombinant cytochrome p450 enzymes as an in vitro system for metabolic clearance predictions

    Stringer, R. A., Strain-Damerell, C., Nicklin, P. & Houston, J. B., May 2009, In : Drug Metabolism and Disposition. 37, 5, p. 1025-1034 9 p.

    Research output: Contribution to journalArticle

  9. Published

    Relative Importance of Intestinal and Hepatic Glucuronidation-Impact on the Prediction of Drug Clearance

    Cubitt, H. E., Houston, J. B. & Galetin, A., May 2009, In : Pharmaceutical Research. 26, 5, p. 1073-1083 10 p.

    Research output: Contribution to journalArticle

  10. Published

    QGut Model as a Predictive Tool for Intestinal Availability in Human: Impact of In Vitro Permeability and Clearance

    Gertz, M., Fenner, KS., Harrison, A., Davis, J., Houston, JB. & Galetin, A., 6 Feb 2009, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  11. Published

    Prediction of drug clearance by glucuronidation from in vitro data: Use of combined cytochrome P450 and UDP-glucuronosyltransferase cofactors in alamethicin-activated human liver microsomes

    Kilford, P. J., Stringer, R., Sohal, B., Houston, J. B. & Galetin, A., Jan 2009, In : Drug Metabolism and Disposition. 37, 1, p. 82-89 7 p.

    Research output: Contribution to journalArticle

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