Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. 2011
  2. Published
  3. Published

    Critique of the two-fold measure of prediction success for ratios: Application for the assessment of drug-drug interactions

    Guest, E. J., Aarons, L., Houston, J. B., Rostami-Hodjegan, A. & Galetin, A., Feb 2011, In : Drug Metabolism and Disposition. 39, 2, p. 170-173 3 p.

    Research output: Contribution to journalArticle

  4. Published

    Assessment of algorithms for predicting drug-drug interactions via inhibition mechanisms: Comparison of dynamic and static models

    Guest, E. J., Rowland-Yeo, K., Rostami-Hodjegan, A., Tucker, G. T., Houston, J. B. & Galetin, A., Jan 2011, In : British Journal of Clinical Pharmacology. 71, 1, p. 72-87 15 p.

    Research output: Contribution to journalArticle

  5. 2010
  6. Published

    Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: Transporter-enzyme interplay

    Brown, H. S., Wilby, A. J., Alder, J. & Houston, J. B., Dec 2010, In : Drug Metabolism and Disposition. 38, 12, p. 2139-2146 7 p.

    Research output: Contribution to journalArticle

  7. Published

    Prediction of human metabolic clearance from in vitro systems: Retrospective analysis and prospective view

    Hallifax, D., Foster, J. A. & Houston, J. B., Oct 2010, In : Pharmaceutical Research. 27, 10, p. 2150-2161 11 p.

    Research output: Contribution to journalArticle

  8. Published

    Contribution of active uptake to the hepatic clearance of seven OATP substrates in rat and human plated hepatocytes

    Menochet, K., Kenworthy, K., Houston, JB. & Galetin, A., Sep 2010, host publication. Vol. 487.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  9. Published

    Drug clearance in different in vitro systems as a preliminary indicator of hepatic uptake

    Houston, J., Rostami-Hochaghan, A. & Galetin, A., Sep 2010, host publication. Vol. 510.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  10. Published

    Metabolite formation kinetics and intrinsic clearance of phenacetin, tolbutamide, alprazolam, and midazolam in adenoviral cytochrome P450-transfected HepG2 cells and comparison with hepatocytes and in vivo

    Donato, M. T., Hallifax, D., Picazo, L., Castell, J. V., Houston, J. B., Gomez-Lechón, M. J. & Lahoz, A., Sep 2010, In : Drug Metabolism and Disposition. 38, 9, p. 1449-1455 6 p.

    Research output: Contribution to journalArticle

  11. Published

    Physiologically-based pharmacokinetic modelling of hepatic transporter substrate rosuvastatin

    Tate, S., Jones, HM., Houston, JB. & Galetin, A., Sep 2010, host publication.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  12. Published
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