Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. 2015
  2. Published

    In vitro assessment of uptake and lysosomal sequestration of respiratory drugs in alveolar macrophage cell line NR8383

    Ufuk, A., Somers, G., Houston, J. & Galetin, A., Dec 2015, In : Pharmaceutical Research. 32, 12, p. 3937–3951 14 p.

    Research output: Contribution to journalArticle

  3. Published

    Assessing metabolic competence in isolated hepatocytes: Exploring the relationship between enzyme function and plasma membrane integrity via Saponin treatment

    Wood, F., Hallifax, D. & Houston, B., Jun 2015, host publication. Vol. P10.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  4. Published

    In Silico Prediction of Hepatocellular Drug Binding

    Assmus, F., Houston, B. & Galetin, A., Jun 2015, host publication. Vol. A10.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  5. Published

    Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins

    Rowland, A., Hallifax, D., Nussio, M., Shapter, J., Mackenzie, P., Houston, J. B., Knights, K. M. & Miners, J. O., 24 Mar 2015, In : Xenobiotica. 45, 10, p. 847-857 10 p.

    Research output: Contribution to journalArticle

  6. Published

    "Time dependent" inhibition of hepatic uptake transporters in hepatocytes and implications on the assessment of transporter-mediated drug-drug interactions

    Kageyama, M., Houston, B. & Galetin, A., 2015, host publication. Vol. P43.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  7. Published

    Comparison of respiratory drug accumulation and lysosomal sequestration in NR8383 and primary human al veolar macrophages

    Ufuk, A., Plumb, J., Houston, B. & Galetin, A., 2015, host publication. Vol. A11.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  8. Published

    Cynomoglus monkey as a preclinical model for the investigation of hepatic uptake of OATP substrates

    Bruyn, T. D., Barton, H. A., Bi, Y-A., Cantrill, C., Galetin, A., Houston, B., Lin, J. & Kosa, R., 2015, host publication. Vol. P11.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  9. Published

    Investigation into LiverChipTM as a 3D hepatocyte model for clearance prediction

    De Bruyn, T., Kageyama, M., Ufuk, A., Hallifax, D., Houston, J. B. & Galetin, A., 2015

    Research output: Other contribution

  10. 2014
  11. Published

    Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition

    Smith, D., Artursson, P., Avdeef, A., Di, L., Ecker, G. F., Faller, B., Houston, J. B., Kansy, M., Kerns, E. H., Krämer, S. D., Lennernäs, H., Van De Waterbeemd, H., Sugano, K. & Testa, B., 2 Jun 2014, In : Molecular Pharmaceutics. 11, 6, p. 1727-1738 11 p.

    Research output: Contribution to journalArticle

  12. Published
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