Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. Article › Research › Peer-reviewed
  2. Published

    Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins

    Rowland, A., Hallifax, D., Nussio, M., Shapter, J., Mackenzie, P., Houston, J. B., Knights, K. M. & Miners, J. O., 24 Mar 2015, In : Xenobiotica. 45, 10, p. 847-857 10 p.

    Research output: Contribution to journalArticle

  3. Published

    Clearance-dependent underprediction of in vivo intrinsic clearance from human hepatocytes: Comparison with permeabilities from artificial membrane (PAMPA) assay, in silico and caco-2 assay, for 65 drugs

    Hallifax, D., Turlizzi, E., Zanelli, U. & Houston, J. B., 11 Apr 2012, In : European Journal of Pharmaceutical Sciences. 45, 5, p. 570-574 4 p.

    Research output: Contribution to journalArticle

  4. Published

    Comparative analysis of CYP3A heteroactivation by steroid hormones and flavonoids in different in vitro systems and potential in vivo implications

    Henshall, J., Galetin, A., Harrison, A. & Houston, J. B., Jul 2008, In : Drug Metabolism and Disposition. 36, 7, p. 1332-1340 8 p.

    Research output: Contribution to journalArticle

  5. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Brian Houston, J., Oosterhuis, B., Bjerrum, O. J., Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 14 Jun 2011, In : European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journalArticle

  6. Published

    Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells

    Andrews, J., Abd-Ellah, M. F., Randolph, N. L., Kenworthy, K. E., Carlile, D. J., Friedberg, T. & Houston, J. B., 1 Nov 2002, In : Xenobiotica. 32, 11, p. 937-947 10 p.

    Research output: Contribution to journalArticle

  7. Published

    Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: Transporter-enzyme interplay

    Brown, H. S., Wilby, A. J., Alder, J. & Houston, J. B., Dec 2010, In : Drug Metabolism and Disposition. 38, 12, p. 2139-2146 7 p.

    Research output: Contribution to journalArticle

  8. Published

    Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs

    Zanelli, U., Caradonna, N. P., Hallifax, D., Turlizzi, E. & Houston, J. B., Jan 2012, In : Drug Metabolism and Disposition. 40, 1, p. 104-110 6 p.

    Research output: Contribution to journalArticle

  9. Published

    Comparison of fresh and cryopreserved rat hepatocyte suspensions for the prediction of in vitro intrinsic clearance

    Griffin, S. J. & Houston, J. B., May 2004, In : Drug Metabolism and Disposition. 32, 5, p. 552-558 6 p.

    Research output: Contribution to journalArticle

  10. Published
  11. Published
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